№ lp_2_3_45158
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Tabulated dataset listing chemical constituents of GXNT with corresponding molecular identifiers and pharmacokinetic indicators including oral bioavailability and drug-likeness values.
Document type:
Supplementary table
Title as given:
S_Table 1 The active ingredients of GXNT and their pharmacokinetic parameters
Subject:
Active ingredients of GXNT and pharmacokinetic parameters
Herb names:
SB; LD
Parameters included:
Mol ID; Molecule Name; OB (%); DL
Abbreviations defined:
OB, Oral bioavailability; DL, Drug-likeness
Note:
* No relevant target was found for this compound
Number of listed compounds:
70+
Language of content:
English
Scientific field:
Pharmacology; Phytochemistry
Format:
Tabular dataset
Price: 8 / 10 USD
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The product description is provided for reference. Actual content and formatting may differ slightly.
Year:
2026
Region / City:
USA, Irvine, CA
Document Type:
Research Study
Institution:
Chapman University, University of California
Author:
Rudy Chang, Devaraj V. Chandrashekar, G. Chuli Roules, Nataraj Jagadeesan, Emi Iwasaki, Adenike Oyegbesan, Hayk Davtyan, Rachita K. Sumbria
Target Audience:
Researchers, Pharmacologists, Neurologists
Period of Validity:
Ongoing, Preclinical phase
Approval Date:
2026
Modification Date:
Not Applicable
Year:
2023
Region / City:
Nashik, Maharashtra, India
Topic:
RNA therapeutics, clinical pharmacokinetics, RNA-based therapies
Document Type:
Review article
Organization:
Krantiveer Vasantrao Narayanrao Naik Shikshan Prasarak Sanstha, Institute of Pharmaceutical Education & Research
Author:
Sakshi L. Bodke, Mayuri N. Jagtap, Avinash B. Darekar
Target Audience:
Researchers, clinicians, pharmaceutical industry professionals
Period of Validity:
Ongoing
Date of Approval:
2023
Date of Changes:
None
Keywords:
RNA therapeutics, clinical pharmacokinetics, pharmacodynamics, absorption
Note:
Contextual Description
Year:
2021
Region / City:
China and Southeast Asia
Subject:
Pharmacology, Ethnobotany, Phytochemistry
Document Type:
Supplementary material / Scientific review data
Institution:
Chengdu University of Traditional Chinese Medicine
Authors:
Qinyun Du, Xianli Meng, Shaohui Wang
Target Audience:
Researchers and professionals in pharmacology and traditional medicine
Data Coverage:
Plant species, pharmacological activities, extraction methods, and chemical properties
Date of Publication:
2021
References Included:
Yes, multiple sources cited for plant species and pharmacological effects
Language:
English
Document Structure:
Tables with plant sources, pharmacological actions, and extraction methods
Type of document:
Supplementary table legends
Research field:
Pharmacology
Research topic:
Metabolism and pharmacokinetics of vemurafenib
Analyzed compound:
Vemurafenib
Metabolite:
OH-vemurafenib
Biological system:
Human liver microsomes (HLM) and transgenic mouse models
Experimental models:
Cyp3aKO/Cyp3a13+/+, huCYP3A4/3A7, huPXR/huCAR/huCYP3A4/3A7, huPXR/huCAR mice
Inducers and treatments:
PCN, RIF, PB, elacridar
Analytical methods:
Hill equation modeling, Michaelis–Menten kinetics, Spearman’s rank correlation
Measured parameters:
Apparent kinetic parameters and pharmacokinetic (PK) parameters
Related figures:
Figure 2, Figure 3, Figure 4, Figure 5
Dose described:
Vemurafenib 100 mg/kg
Statistical notes:
Comparisons between vehicle and treatment groups with significance indicators
Year:
2018
Country:
United States
Subject:
Pharmacokinetics and pharmacodynamics of meropenem in pediatric sepsis
Document Type:
Supplemental scientific tables and figures
Drug:
Meropenem
Pathogen Focus:
Pseudomonas aeruginosa
Data Source:
SENTRY Antimicrobial Surveillance Program
Study Population:
Children younger than 17 years
Clinical Condition:
Sepsis
Parameters Analyzed:
Observed volume of distribution (Vz_obs), observed clearance (Cl_obs), minimum inhibitory concentration (MIC), pharmacodynamic target attainment (T>MIC), estimated glomerular filtration rate (eGFR), fluid balance
Dosage Regimens Evaluated:
20 mg/kg, 40 mg/kg, 60 mg/kg
Evaluation Period:
Day 1 to Day 3 after start of meropenem infusion
Geographic Scope of Isolate Data:
United States medical centers
Organization:
World Health Organization; South African Health Products Regulatory Authority
Document type:
Regulatory guideline
Subject area:
Pharmaceutical quality documentation
Scope:
Multisource (generic) finished pharmaceutical products and active pharmaceutical ingredients
Applicable products:
Human medicines; biologics; veterinary medicines
Regulatory references:
WHO TRS 970 Annex 6; VICH guidelines; European Pharmacopoeia; USP; BP
Geographical applicability:
International; South Africa
Related regulatory procedures:
API Prequalification; CEP; APIMF; product dossier submission
Content focus:
Quality data requirements; labelling and product information; drug substance characterization
Intended users:
Marketing authorization applicants; regulatory assessors
Year:
2021
Region / city:
Not specified
Topic:
Temperature control, milk storage, dairy products
Document type:
Program Document
Organization / institution:
Company Name
Author:
Kathy Glass, Alex O’Brien
Target audience:
Employees involved in raw material handling and dairy production
Period of validity:
Not specified
Approval date:
Not specified
Amendment date:
Not specified
Year:
N/A
Region / City:
N/A
Subject:
Analytical methods for pesticide residue determination
Document Type:
Methodology
Organization / Institution:
N/A
Author:
N/A
Target Audience:
Regulatory authorities, pesticide testing laboratories
Validity Period:
N/A
Approval Date:
N/A
Date of Modifications:
N/A
Note:
Contextual description
Year:
2019
Region / City:
Global
Topic:
Sustainable Sourcing, Palm Oil
Document Type:
Corporate Report
Organization / Institution:
NUXE
Author:
NUXE
Target Audience:
Consumers, Industry Partners, Sustainability Advocates
Period of Validity:
Ongoing
Date of Approval:
2019
Date of Changes:
N/A
Note:
Year
Topic:
Culinary Science
Document type:
Educational Instructions
Target audience:
Students
Document Type:
Food product ingredient and nutritional information list
Content Category:
Prepared meals and entrees
Items Included:
Asian Cashew Chicken; Beef Florentine Casserole; Chicken Burrito Bowls; Chicken Pot Pie Empanadas; Chicken With Prosciutto & Sage; Creole Fish Chowder; Italian Sausage Lasagna; Pina Colada Shrimp; Primavera Ravioli Bake
Information Provided:
Ingredients; Nutritional Information; Allergen Statements; Gluten Status (where applicable)
Allergens Declared:
Peanuts; Cashews; Soy; Gluten; Milk; Wheat; Fish; Egg; Shellfish
Nutritional Elements Listed:
Calories; Fat; Saturated Fat; Carbohydrates; Fiber; Sodium; Protein; Sugar
Gluten Status Statements:
Naturally Gluten Free (for selected items)
Language:
English
Note:
Year
Theme:
Cooking / Recipe
Document Type:
Recipe
Context:
A recipe for preparing Ratatouille, detailing ingredients, method, and tips for variation and serving suggestions.
Year:
2012
Region / city:
EU
Topic:
Household cleaning products, enzymes, risk assessment
Document type:
Scientific report
Organization:
AMFEP
Author:
Various authors (listed in the references)
Target audience:
Researchers, regulatory bodies, industry professionals
Effective date:
1st February 2012
Date of revisions:
N/A
Year:
2020
Region / city:
Taipei, Taiwan
Subject:
Food safety, food regulation
Document type:
Draft regulation
Agency / institution:
Food and Drug Administration, Ministry of Health and Welfare, Taiwan
Author:
Food and Drug Administration, Ministry of Health and Welfare
Target audience:
Regulatory bodies, food industry
Period of validity:
To be determined
Approval date:
To be determined
Amendment date:
N/A
Year:
2023
Region / city:
European Union
Theme:
Wine Industry Regulations
Document type:
Feedback
Organization:
Comité Européen des Entreprises Vins (CEEV)
Author:
Comité Européen des Entreprises Vins (CEEV)
Target audience:
Wine producers, regulators, wine industry stakeholders
Period of validity:
Indefinite
Approval date:
17/02/2023
Date of changes:
None
Context description:
Feedback on European Commission regulations for ingredient labelling in wine production, addressing clarity and legal certainty for producers and consumers.
Note:
Year
Contextual Description:
A checklist for embedding Education for the Sustainable Development Goals (SDGs) into taught courses, highlighting key actions for integrating sustainability and assessing their impact.
Year:
2025
Origin:
France and Italy
Topic:
Culinary arts / Pastry
Document type:
Educational / Instructional text
Author:
Swarup Saha
Contributors:
S C Dubey, P S Bali
Intended audience:
Culinary students, pastry enthusiasts
Last updated:
24/01/2025
Key products:
Profiteroles, Croquembouche, St. Honoré Cake, Paris-Brest, Pomme Dauphine, Gnocchi Parisenne
Main ingredients:
Flour, water, milk, eggs, butter, sugar, vanilla essence
Preparation methods:
Panada dough, baking, piping, filling techniques
Historical context:
Evolution from Italian pâte à Panterelli to modern French choux pastry
Note:
Year
Topic:
Cooking Recipe
Document Type:
Recipe
Note:
Year
Topic:
Culinary Arts
Document Type:
Practical Work Guidelines
Target Audience:
Students
Year:
2024
Organization:
TLC Ingredients
Document Type:
Policy
Scope:
All procurement activities, employees, suppliers, contractors, and partners
Principles:
Environmental responsibility, social responsibility, economic viability, innovation and continuous improvement
Responsible Person:
President of TLC Ingredients
Associated Documents:
TLC Corporate Social Responsibility Program (RD-006-01-XX), RD Code VI: Sustainability (RD-006-XX)
Revision History:
Revision 1, 03/05/2024, New Document