№ files_lp_4_process_2_63478
File format: docx
Character count: 39018
File size: 996 KB
Year:
2006-2014
Region:
Iowa and North Carolina, USA; Augsburg, Germany
Topic:
Epigenetics, Alcohol consumption, Blood pressure
Document type:
Supplemental materials / Research data description
Institution:
National Institute of Environmental Health Sciences; Cooperative Health Research in the Region Augsburg (KORA)
Authors:
Bui, Keshawarz, Wang et al.
Study design:
Case-control study (ALHS); Population-based cohort (KORA)
Participants:
Farmers and spouses (ALHS); General population aged 25-74 (KORA)
Sample size:
3,301 (ALHS); 1,802 (KORA F4)
Data collected:
DNA methylation, clinical and behavioral phenotypes, alcohol consumption, smoking status
Consent and approval:
Informed consent obtained; Institutional Review Board approval (ALHS)
Funding:
Intramural Research Program of the NIH, National Cancer Institute, American Recovery and Reinvestment Act funds
Analytical methods:
DNA methylation measurement with EPIC and 450K BeadChips, quality control, normalization, cell type estimation, statistical regression analyses
Price: 8 / 10 USD
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Document type:
Supplementary material to a scientific research article
Subject:
Genetic and epigenetic variation in Corydalis yanhusuo populations
Species:
Corydalis yanhusuo
Analytical methods:
STRUCTURE analysis; dbRDA; AFLP; MSAP
Content:
Supplementary figures (S1–S2) and tables (S1–S6)
Populations analyzed:
17 populations (cultivated and natural)
Data included:
Methylation frequencies; primer and adapter sequences; monthly mean weather parameters; pairwise FST values
Genetic markers:
AFLP
Epigenetic markers:
MSAP
Chemical variables:
Tetrahydropalmatine; Protopine; Palmatine; Berberine
Environmental variables:
Air pressure; temperature; relative humidity; precipitation; sunshine duration
Document Type:
Supplemental figure legends
Field:
Molecular biology
Research Area:
Gastrointestinal epithelium and intestinal metaplasia
Subjects:
CDX2, HNF4A, SOX2, gastric organoids, Barrett’s esophagus, gastric intestinal metaplasia
Biological Material:
Human gastrointestinal tissues and mouse stomach organoids
Methods:
Single-cell RNA-seq, bulk RNA-seq, ATAC-seq, CUT&RUN, ChIP-seq, GSEA, enhancer analysis, immunohistochemistry, qRT-PCR
Referenced Studies:
Busslinger et al. 2021b; Nowicki-Osuch et al. 2021; Owen et al. 2018; Companioni et al. 2017; Singh et al. 2021; Gao and Kaestner 2010; Wang et al. 2013
Key Topics:
Transcriptional profiling, chromatin accessibility, enhancer activity, transcription factor binding, intestinalization of gastric epithelium
Species:
Homo sapiens; Mus musculus
Pathological Context:
Barrett’s esophagus; gastric intestinal metaplasia
Year:
2023
Author:
Jacob Ivy
Field of study:
Biology, Pre-Med
Department:
Microbiology and Molecular Genetics, Oklahoma State University
Location:
Stillwater, OK, USA
Type of document:
Research article
Keywords:
Epigenetics, Biomarkers, Nanoparticles, Methylation
Target audience:
Researchers and students in molecular biology and oncology
Scope:
Diagnostic and therapeutic applications of epigenetic factors in cancer
Recent developments:
Site-specific cancer drugs, epigenetic biomarkers, nanoparticle delivery systems
Sources cited:
Roberti et al., 2019; Villanueva et al., 2020
Year:
2024
Region / City:
Bodø, Norway; Edinburgh, Scotland; Barcelona, Spain
Subject:
Reproductive endocrinology, teleost puberty
Document type:
Research article
Institution:
Nord University, The Roslin Institute, Institute of Marine Science (ICM)
Authors:
L. Colonna, I. Konstantinidis, R.R. Daniels, D. Robledo, J.M.O. Fernandes
Target audience:
Researchers in marine biology and fish physiology
Methodology:
Single-cell RNA-seq and ATAC-seq profiling
Model organism:
Nile tilapia (Oreochromis niloticus)
Experimental conditions:
Continuous and ambient light exposure for 4 months
Purpose:
Identification of pituitary cell types and markers associated with puberty onset in teleosts
Reference:
M. Li, L. Sun, L. Zhou & D. Wang (2024). Gen Comp Endocrinol 345:114395
Document type:
Research proposal section
Research area:
Systems biology and epigenetics
Scientific field:
Gene regulatory network modeling
Research focus:
Integration of epigenetic regulators into gene network inference
Model organism:
Arabidopsis thaliana
Key regulator studied:
SET Domain Group 8 (SDG8)
Homologous human protein:
SETD2
Epigenetic mechanism:
H3K36 histone methylation
Biological processes referenced:
Gene regulation and chromatin modification
Methodological approaches:
Time-course transcriptome analysis, predictive network modeling, dynamic Bayesian networks, state-space modeling
Data sources referenced:
Epigenomics datasets and ENCODE resources
Research objectives:
Identification of genomic targets of epigenetic regulators and evaluation of their role as predictors in gene regulatory network models
Proposed framework:
EpiNet
Research components:
Significance, Innovation, and Approaches
Experimental strategy:
Integration of experimental perturbation data with computational network inference
Year:
2026
Organization:
Preschool Access for All Learning Network
Document Type:
Mini-Grant Guidance
Target Audience:
Educators, Paraprofessionals, District Inclusion Teams
Age Group:
Children with disabilities, ages 3–5
Focus Areas:
Inclusive opportunities, developmentally appropriate environments, high-quality instruction
Expenditure Categories:
Instructional supplies and materials, in-service/staff development
Contact:
Misty Moody, Assistant Commissioner of Early Learning, [email protected]
Document Purpose:
Provide guidelines for mini-grant expenditures to support inclusion and developmentally appropriate practices
Year:
2024
Region / city:
UK
Subject:
Safer staffing in healthcare
Document type:
Application form
Organization / institution:
NHS England
Author:
NHS England
Target audience:
Healthcare professionals, Trust management
Duration:
2024-2025
Approval date:
Not specified
Modification date:
Not specified
Year:
2018-19
Region / city:
United States
Theme:
Education, Graduation Rates
Document type:
Technical Guide
Organization / institution:
U.S. Department of Education
Author:
Brandon Scott
Target audience:
Educational administrators, State Education Agencies (SEAs), Local Education Agencies (LEAs)
Period of validity:
SY 2018-19
Approval date:
October 2018
Date of changes:
October 2018
Year:
2021
Region / City:
Global
Topic:
Copy number variation, autism spectrum disorder
Document type:
Research methodology
Organization / Institution:
Various academic institutions and research groups
Author:
Multiple authors (see references)
Target audience:
Researchers, clinicians in genetics and autism studies
Period of validity:
2021 and onwards
Approval date:
N/A
Date of revisions:
N/A
Note:
Contextual description
Year:
2022
Location:
Bakersfield, CA
Field:
Educational Leadership
Document Type:
Student Handbook
Organization:
California State University, Bakersfield (CSUB)
Author:
DPEL Graduate Group
Target Audience:
Doctoral students, dissertation chairs, faculty, administrative staff
Action Period:
2022
Approval Date:
February 20, 2022
Date of Changes:
February 20, 2022
Year:
2020
Region / Institution:
University College London
Programme:
DPUK Work Package 5
Related Work Packages:
WP3 (UK Biobank), WP4 (1946 birth cohort), WP6
Thematic Area:
Neurodegenerative diseases and biomarkers
Diseases Covered:
Familial Alzheimer’s disease, Familial frontotemporal dementia, Huntington’s disease, Familial Parkinson’s disease (LRRK2)
Cohorts:
UCL FAD, DIAN, GENFI, Track HD, LRRK2 cohort
Type of Document:
Research programme summary and output report
Organ / Institution:
University College London
Collaborating Initiatives:
DIAN, GENFI, Track HD, UK Biobank
Main Biomarkers Studied:
Serum neurofilament light (NfL), plasma phospho-tau181, cortical mean diffusivity, PET imaging markers
Study Population:
Individuals with autosomal dominant inherited neurodegenerative diseases and non-mutation carrier siblings
Research Focus:
Presymptomatic to symptomatic disease progression and biomarker validation
Outputs:
Peer-reviewed publications and longitudinal cohort analyses
Document type:
Supplementary tables from a scientific research study
Research field:
Oncology; Cancer genomics
Disease focus:
Prostate cancer
Study design:
Retrospective cohort analysis
Cohorts included:
JHMI; Mayo; TJU; Durham; Kaiser; BWH; TCGA
Tissue type:
Radical prostatectomy specimens and biopsy samples
Total sample sizes:
Cohorts ranging from 100 to 355 patients
Clinical variables:
Age at diagnosis; PSA at diagnosis; Gleason Grade Group; ADT treatment status; metastatic outcome or recurrence; follow-up duration
Statistical measures:
Adjusted p-values after FDR multiple test correction; hazard ratios; confidence intervals; p-values
Genetic markers analyzed:
DNA repair signatures; immune cell signatures; mismatch repair genes; neuroendocrine markers; multiple individual genes (e.g., PMS2, MLH1, ESR1, SOX2)
Outcome measures:
Metastatic progression or recurrence
Statistical models:
Batch-stratified competing risks regression
Key variables in regression:
AR-A expression level; Gleason grade ≥8; surgical margins; PSA level; age at radical prostatectomy; ADT treatment type; extracapsular extension; seminal vesicle invasion; lymph node invasion
Follow-up period:
Median follow-up ranging from 28 to 108 months across cohorts
Year:
2023
Region / City:
Bellevue, Washington
Topic:
Nursing Program Admission Requirements
Document Type:
Admission Guidelines
Organization:
Bellevue College
Author:
Bellevue College
Target Audience:
Prospective Nursing Students
Admission Period:
Fall 2023 and onward
Date of Approval:
Winter 2024
Date of Changes:
Winter 2024
Year:
2016
Region / City:
Global
Topic:
Alcohol genetics, GWAS
Document type:
Research study
Organization / Institution:
Alcohol Genome-wide Association (AlcGen) Consortium, Cohorts for Heart and Aging Research in Genomic Epidemiology Plus (CHARGE +) Consortium
Author:
Not specified
Target audience:
Researchers, geneticists, epidemiologists
Period of validity:
Not applicable
Date of approval:
Not applicable
Date of modifications:
Not applicable
Year:
2026-2027
Region / City:
Not specified
Subject:
Veterinary Medicine, Continuing Education
Document Type:
Course Schedule
Institution:
Not specified
Author:
Not specified
Target Audience:
Veterinary professionals
Period of Validity:
September 2026 - July 2027
Approval Date:
Not specified
Date of Modifications:
Not specified
Year:
2022
Region / city:
Italy, United Kingdom
Topic:
Sero-epidemiology, Multiple Sclerosis, Herpesviruses
Document type:
Research Protocol
Organization / institution:
N/A
Author:
Bruno Gran, Peter Maple, Chris Tench
Target audience:
Researchers, Medical professionals
Duration:
N/A
Approval date:
05 September 2022
Modification date:
N/A
Year:
2025
Country:
United States
Region:
Washington, DC
Issuing organization:
U.S. Department of Education
Program / system:
EDFacts
File identifier:
FS151
Version:
22.0
Publication date:
October 2025
Document type:
Technical specification
Subject:
Education data reporting and graduation rate cohorts
Related file specification:
FS150 Adjusted Cohort Graduation Rate
Data groups:
696, 698, 756, 851, 853, 855, 857
Collection authority:
Annual Mandatory Collection of Elementary and Secondary Education Data Through EDFacts (OMB 1850-0925)
Reporting entities:
State education agencies (SEAs)
Data scope:
State, local educational agency, and school level
Submission system:
EDPass
Contractor:
AEM Corporation
Contract number:
91990024F0331
Public domain status:
Public domain, reproduction permitted
Document type:
Supplemental digital content
Content components:
Figures and tables
Subject area:
Oncology
Research focus:
Survival analysis and clinicopathological characteristics
Clinical variables:
Retrieved lymph nodes, chemoradiotherapy, adjuvant therapy, tumor stage and size
Patient groups:
N0 and N1 patients
Data sources:
WUH cohort and SEER cohort
Institutions / databases:
Wuhan Union Hospital; Surveillance, Epidemiology, and End Results program
Measured outcomes:
Overall survival and prognostic differences
Clinical treatments analyzed:
Chemotherapy, radiotherapy, chemoradiotherapy
Population characteristics:
Age, sex, BMI, tumor grade, tumor stage, tumor size, nerve invasion, vascular invasion
Tables included:
Clinicopathological features before and after propensity score matching
Figures included:
Survival curves and cutoff value analyses for retrieved lymph nodes
Year:
2023
Datasets:
TRITON2, TRITON3, FMI
Sample Size:
TRITON2 n=856, TRITON3 n=818, FMI n=1660
Genes Analyzed:
AR, BRCA1, BRCA2
Analysis Method:
Fisher’s Exact Test, Benjamini-Hochberg correction
Variant Types:
SV, RE, AMP
Data Subset Size:
FMI n=717, TRITON2 n=750, TRITON3 n=746
Year:
2026
Type of document:
Supplementary table
Topic:
Oncology / Clinical trial biomarkers
Cohorts:
A-D
Variables analyzed:
CDR, PFS, VAF, gene mutations
Statistical methods:
Hazard ratio, Harrell’s C, median comparison
Mutations considered:
ESR1 included/excluded, clonal, combined, weighted, mean
Measurement points:
C1D1, C2D1
Target audience:
Clinical researchers, oncologists
Source:
Clinical trial data
Description:
Tabular data from a clinical study showing comparisons of various computational approaches to predict clinical response rates and progression-free survival based on mutation allele frequencies.