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This document is a study protocol for investigating the association between human herpesviruses and multiple sclerosis through sero-epidemiological data from Italian and UK patient cohorts and controls.
Year: 2022
Region / city: Italy, United Kingdom
Topic: Sero-epidemiology, Multiple Sclerosis, Herpesviruses
Document type: Research Protocol
Organization / institution: N/A
Author: Bruno Gran, Peter Maple, Chris Tench
Target audience: Researchers, Medical professionals
Duration: N/A
Approval date: 05 September 2022
Modification date: N/A
Price: 8 / 10 USD
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dsDNA (Crithidia l.) kit: Indirect fluorescent antibody assay for anti-dsDNA IgG antibodies in human sera
Note: Year
Does the antibody production ability affect the serum anti-Helicobacter pylori IgG titer?
Journal: World Journal of Gastrointestinal Pathophysiology
Manuscript Type: Original Article
Study Design: Retrospective Cohort Study
Authors: Hyun Ah Chung; Sun-Young Lee; Hee Won Moon; Jeong Hwan Kim; In-Kyung Sung; Hyung Seok Park; Chan Sup Shim; Hye Seung Han
Affiliations: Department of Internal Medicine, Department of Laboratory Medicine, and Department of Pathology, Konkuk University School of Medicine, Seoul 05030, South Korea
Corresponding Author: Sun-Young Lee, MD, PhD
Country: South Korea
Funding: Supported by Konkuk University in 2015 (No. KU2015-A019-0270)
Institutional Review Board Approval: Konkuk University School of Medicine (KUH1010625)
Clinical Trial Registration: ClinicalTrials.gov ID: KCT0001302
Received: December 27, 2015
Accepted: July 11, 2016
Publication Year: 2016
Keywords: Antibody; Helicobacter pylori; Hepatitis B; Immunoglobulin G; Pepsinogen
License: Creative Commons Attribution Non Commercial (CC BY-NC 4.0)
Supplemental Table 1. Anti-SARS-CoV-2 Spike Protein IgG Seroconversion Rates in Patients with Hematologic Malignancies and Healthy Volunteers after COVID-19 Vaccination
Document Type: Supplemental table
Topic: Anti-SARS-CoV-2 spike protein IgG seroconversion
Subject: Hematologic malignancies and healthy controls
Medical Context: COVID-19 vaccination response
Vaccines Included: BNT162b2; mRNA1273; Ad26.COV2.S; ChyAdOx1
Antibody Test Platforms: Elecsys; AdviseDx Abbott; Liaison; DBS; Sero-Klir Kantaro; Beckman Coulter; Sino Biological; Meso Scale Discovery; Platelia
Countries Represented: United States; United Kingdom; Israel; Denmark; Italy
Patient Groups: ALL/AML; CLL; CML/MPD; MDS; WM; MM; NHL; Healthy controls
Sample Size Range per Study: 21–650 participants
Combined Healthy Control Sample Size: 729
Primary Outcome Measure: Seroconversion rate after full vaccination
Source Basis: Published and in-press peer-reviewed studies
IgG Antibody Panel Testing Procedure on Immucor Galileo Echo
Instrument: Immucor Galileo Echo
Test Panels: Capture-R Ready-ID; Capture-R Extend I; Capture-R Extend II
Test Method: IgG antibody panel using Capture-R technology
Temperature: 37°C
Specimen Type: EDTA anticoagulated whole blood; serum from fully clotted blood
Specimen Stability: ≤5 days from collection; ≤4 days for recently transfused or pregnant patients
Exclusion Criteria: Hemolyzed (≥3+), lipemic, or icteric samples not accepted
Reagents: Capture LISS; Capture-R Ready-ID; Capture-R Extend I & Extend II; Capture-R Indicator Cells; WB corQC; PHIX buffered saline
Equipment: Immucor Galileo Echo
Quality Control: Commercial WB corQC performed daily; 24-hour control interval after validation
Controls: Positive and negative controls included in each 14-cell panel
Related Policy: SWIM manual NRT.007 “Antibody Identification of Warm Reactive Antibodies”
Reporting: Results reviewed and confirmed by technologist; specimens forwarded for additional antibody testing if required
Restrictions: Partially used strips cannot be reused
References: Galileo Echo Operator Manual; SWIM manual
ZEUS ELISA EBNA-1 IgG Test System for Detection of Epstein-Barr Virus Antibodies in Human Serum
Year: 2026
Region / City: Not specified
Subject: Clinical diagnostics, virology
Document Type: In vitro diagnostic test instructions
Organization: ZEUS Scientific, Inc.
Author: Not specified
Target Audience: Laboratory personnel
Period of Use: Ongoing
Date of Issue: 2026
Safety Precautions: Biosafety Level 2, toxic and irritant reagents handling instructions included
Components: Microplate strips, conjugate, controls, calibrator, diluent, substrate, stop solution, wash buffer
Intended Sample: Human serum
Test Principle: ELISA detection of IgG antibodies to EBV Nuclear Antigen 1 (EBNA-1)
Assay Procedure: Three-step incubation with antigen-coated wells, conjugate, and substrate followed by photometric measurement
Supplementary material: Prevalence of C. trachomatis MOMP IgG antibodies in RA-FDR and RA patients
Note: Year
Topics: Sero-epidemiological herpesviruses IgG