№ lp_2_3_45241
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This document outlines the methodologies and statistical models used in the detection and analysis of copy number variations (CNVs) within various autism spectrum disorder (ASD) cohorts, including SSC, MSSNG, and Generation Scotland.
Year:
2021
Region / City:
Global
Topic:
Copy number variation, autism spectrum disorder
Document type:
Research methodology
Organization / Institution:
Various academic institutions and research groups
Author:
Multiple authors (see references)
Target audience:
Researchers, clinicians in genetics and autism studies
Period of validity:
2021 and onwards
Approval date:
N/A
Date of revisions:
N/A
Note:
Contextual description
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Year:
2026
Organization:
Preschool Access for All Learning Network
Document Type:
Mini-Grant Guidance
Target Audience:
Educators, Paraprofessionals, District Inclusion Teams
Age Group:
Children with disabilities, ages 3–5
Focus Areas:
Inclusive opportunities, developmentally appropriate environments, high-quality instruction
Expenditure Categories:
Instructional supplies and materials, in-service/staff development
Contact:
Misty Moody, Assistant Commissioner of Early Learning, [email protected]
Document Purpose:
Provide guidelines for mini-grant expenditures to support inclusion and developmentally appropriate practices
Year:
2024
Region / city:
UK
Subject:
Safer staffing in healthcare
Document type:
Application form
Organization / institution:
NHS England
Author:
NHS England
Target audience:
Healthcare professionals, Trust management
Duration:
2024-2025
Approval date:
Not specified
Modification date:
Not specified
Year:
2018-19
Region / city:
United States
Theme:
Education, Graduation Rates
Document type:
Technical Guide
Organization / institution:
U.S. Department of Education
Author:
Brandon Scott
Target audience:
Educational administrators, State Education Agencies (SEAs), Local Education Agencies (LEAs)
Period of validity:
SY 2018-19
Approval date:
October 2018
Date of changes:
October 2018
Year:
2022
Location:
Bakersfield, CA
Field:
Educational Leadership
Document Type:
Student Handbook
Organization:
California State University, Bakersfield (CSUB)
Author:
DPEL Graduate Group
Target Audience:
Doctoral students, dissertation chairs, faculty, administrative staff
Action Period:
2022
Approval Date:
February 20, 2022
Date of Changes:
February 20, 2022
Year:
2020
Region / Institution:
University College London
Programme:
DPUK Work Package 5
Related Work Packages:
WP3 (UK Biobank), WP4 (1946 birth cohort), WP6
Thematic Area:
Neurodegenerative diseases and biomarkers
Diseases Covered:
Familial Alzheimer’s disease, Familial frontotemporal dementia, Huntington’s disease, Familial Parkinson’s disease (LRRK2)
Cohorts:
UCL FAD, DIAN, GENFI, Track HD, LRRK2 cohort
Type of Document:
Research programme summary and output report
Organ / Institution:
University College London
Collaborating Initiatives:
DIAN, GENFI, Track HD, UK Biobank
Main Biomarkers Studied:
Serum neurofilament light (NfL), plasma phospho-tau181, cortical mean diffusivity, PET imaging markers
Study Population:
Individuals with autosomal dominant inherited neurodegenerative diseases and non-mutation carrier siblings
Research Focus:
Presymptomatic to symptomatic disease progression and biomarker validation
Outputs:
Peer-reviewed publications and longitudinal cohort analyses
Document type:
Supplementary tables from a scientific research study
Research field:
Oncology; Cancer genomics
Disease focus:
Prostate cancer
Study design:
Retrospective cohort analysis
Cohorts included:
JHMI; Mayo; TJU; Durham; Kaiser; BWH; TCGA
Tissue type:
Radical prostatectomy specimens and biopsy samples
Total sample sizes:
Cohorts ranging from 100 to 355 patients
Clinical variables:
Age at diagnosis; PSA at diagnosis; Gleason Grade Group; ADT treatment status; metastatic outcome or recurrence; follow-up duration
Statistical measures:
Adjusted p-values after FDR multiple test correction; hazard ratios; confidence intervals; p-values
Genetic markers analyzed:
DNA repair signatures; immune cell signatures; mismatch repair genes; neuroendocrine markers; multiple individual genes (e.g., PMS2, MLH1, ESR1, SOX2)
Outcome measures:
Metastatic progression or recurrence
Statistical models:
Batch-stratified competing risks regression
Key variables in regression:
AR-A expression level; Gleason grade ≥8; surgical margins; PSA level; age at radical prostatectomy; ADT treatment type; extracapsular extension; seminal vesicle invasion; lymph node invasion
Follow-up period:
Median follow-up ranging from 28 to 108 months across cohorts
Year:
2023
Region / City:
Bellevue, Washington
Topic:
Nursing Program Admission Requirements
Document Type:
Admission Guidelines
Organization:
Bellevue College
Author:
Bellevue College
Target Audience:
Prospective Nursing Students
Admission Period:
Fall 2023 and onward
Date of Approval:
Winter 2024
Date of Changes:
Winter 2024
Year:
2016
Region / City:
Global
Topic:
Alcohol genetics, GWAS
Document type:
Research study
Organization / Institution:
Alcohol Genome-wide Association (AlcGen) Consortium, Cohorts for Heart and Aging Research in Genomic Epidemiology Plus (CHARGE +) Consortium
Author:
Not specified
Target audience:
Researchers, geneticists, epidemiologists
Period of validity:
Not applicable
Date of approval:
Not applicable
Date of modifications:
Not applicable
Year:
2026-2027
Region / City:
Not specified
Subject:
Veterinary Medicine, Continuing Education
Document Type:
Course Schedule
Institution:
Not specified
Author:
Not specified
Target Audience:
Veterinary professionals
Period of Validity:
September 2026 - July 2027
Approval Date:
Not specified
Date of Modifications:
Not specified
Year:
2022
Region / city:
Italy, United Kingdom
Topic:
Sero-epidemiology, Multiple Sclerosis, Herpesviruses
Document type:
Research Protocol
Organization / institution:
N/A
Author:
Bruno Gran, Peter Maple, Chris Tench
Target audience:
Researchers, Medical professionals
Duration:
N/A
Approval date:
05 September 2022
Modification date:
N/A
Year:
2025
Country:
United States
Region:
Washington, DC
Issuing organization:
U.S. Department of Education
Program / system:
EDFacts
File identifier:
FS151
Version:
22.0
Publication date:
October 2025
Document type:
Technical specification
Subject:
Education data reporting and graduation rate cohorts
Related file specification:
FS150 Adjusted Cohort Graduation Rate
Data groups:
696, 698, 756, 851, 853, 855, 857
Collection authority:
Annual Mandatory Collection of Elementary and Secondary Education Data Through EDFacts (OMB 1850-0925)
Reporting entities:
State education agencies (SEAs)
Data scope:
State, local educational agency, and school level
Submission system:
EDPass
Contractor:
AEM Corporation
Contract number:
91990024F0331
Public domain status:
Public domain, reproduction permitted
Year:
2006-2014
Region:
Iowa and North Carolina, USA; Augsburg, Germany
Topic:
Epigenetics, Alcohol consumption, Blood pressure
Document type:
Supplemental materials / Research data description
Institution:
National Institute of Environmental Health Sciences; Cooperative Health Research in the Region Augsburg (KORA)
Authors:
Bui, Keshawarz, Wang et al.
Study design:
Case-control study (ALHS); Population-based cohort (KORA)
Participants:
Farmers and spouses (ALHS); General population aged 25-74 (KORA)
Sample size:
3,301 (ALHS); 1,802 (KORA F4)
Data collected:
DNA methylation, clinical and behavioral phenotypes, alcohol consumption, smoking status
Consent and approval:
Informed consent obtained; Institutional Review Board approval (ALHS)
Funding:
Intramural Research Program of the NIH, National Cancer Institute, American Recovery and Reinvestment Act funds
Analytical methods:
DNA methylation measurement with EPIC and 450K BeadChips, quality control, normalization, cell type estimation, statistical regression analyses
Document type:
Supplemental digital content
Content components:
Figures and tables
Subject area:
Oncology
Research focus:
Survival analysis and clinicopathological characteristics
Clinical variables:
Retrieved lymph nodes, chemoradiotherapy, adjuvant therapy, tumor stage and size
Patient groups:
N0 and N1 patients
Data sources:
WUH cohort and SEER cohort
Institutions / databases:
Wuhan Union Hospital; Surveillance, Epidemiology, and End Results program
Measured outcomes:
Overall survival and prognostic differences
Clinical treatments analyzed:
Chemotherapy, radiotherapy, chemoradiotherapy
Population characteristics:
Age, sex, BMI, tumor grade, tumor stage, tumor size, nerve invasion, vascular invasion
Tables included:
Clinicopathological features before and after propensity score matching
Figures included:
Survival curves and cutoff value analyses for retrieved lymph nodes
Year:
2023
Datasets:
TRITON2, TRITON3, FMI
Sample Size:
TRITON2 n=856, TRITON3 n=818, FMI n=1660
Genes Analyzed:
AR, BRCA1, BRCA2
Analysis Method:
Fisher’s Exact Test, Benjamini-Hochberg correction
Variant Types:
SV, RE, AMP
Data Subset Size:
FMI n=717, TRITON2 n=750, TRITON3 n=746
Year:
2026
Type of document:
Supplementary table
Topic:
Oncology / Clinical trial biomarkers
Cohorts:
A-D
Variables analyzed:
CDR, PFS, VAF, gene mutations
Statistical methods:
Hazard ratio, Harrell’s C, median comparison
Mutations considered:
ESR1 included/excluded, clonal, combined, weighted, mean
Measurement points:
C1D1, C2D1
Target audience:
Clinical researchers, oncologists
Source:
Clinical trial data
Description:
Tabular data from a clinical study showing comparisons of various computational approaches to predict clinical response rates and progression-free survival based on mutation allele frequencies.
Year:
2023
Region / city:
Europe
Topic:
Satellite communications, MSS services, 2 GHz frequency band
Document type:
Report
Organization / institution:
CEPT, EU Radio Spectrum Policy Group
Author:
Not specified
Target audience:
Stakeholders in satellite communications, EU regulatory bodies, telecom operators
Period of validity:
Not specified
Approval date:
Not specified
Date of changes:
Not specified
Year:
2023
Region / city:
European Union
Topic:
Satellite Communications, Mobile-Satellite Services (MSS), Frequency Regulation
Document Type:
Draft Response
Organ / institution:
CEPT, WGFM, ECC
Author:
FM44
Target audience:
Policy Makers, Telecommunications Authorities, Satellite Service Providers
Period of validity:
Not specified
Approval date:
Not specified
Date of amendments:
Not specified
Context:
A draft response outlining current and future developments in satellite communications and MSS services, focusing on the 2 GHz frequency band and related regulatory aspects within the EU.
Year:
2021
Region / City:
Africa
Theme:
Spectrum Allocation, Telecommunications
Document Type:
Planning Document
Organization / Institution:
African Telecommunications Union (ATU)
Author:
African Telecommunications Union (ATU)
Target Audience:
African National Regulators, Telecommunications Policy Makers
Period of Validity:
Ongoing, updated after each World Radiocommunications Conference (WRC)
Approval Date:
August 2021
Date of Revision:
After each WRC
Language:
English
Year:
2020
Region / city:
N/A
Theme:
IAB operation in paired spectrum
Document type:
Meeting document
Organization / institution:
3GPP TSG-RAN WG1
Author:
AT&T
Target audience:
RAN1 participants
Period of validity:
N/A
Approval date:
N/A
Date of amendments:
N/A
Year:
2025
Region / city:
United States
Topic:
Spectrum sharing, defense technology
Document type:
Proposal guidance, FAQ
Organization / institution:
U.S. Department of Defense (DoD)
Author:
U.S. Government
Target audience:
Contractors, proposal applicants
Period of validity:
2025
Approval date:
Not specified
Date of changes:
Not specified