№ files_lp_4_process_2_46522
File format: docx
Character count: 8743
File size: 36 KB
Year:
2023
Author:
Jacob Ivy
Field of study:
Biology, Pre-Med
Department:
Microbiology and Molecular Genetics, Oklahoma State University
Location:
Stillwater, OK, USA
Type of document:
Research article
Keywords:
Epigenetics, Biomarkers, Nanoparticles, Methylation
Target audience:
Researchers and students in molecular biology and oncology
Scope:
Diagnostic and therapeutic applications of epigenetic factors in cancer
Recent developments:
Site-specific cancer drugs, epigenetic biomarkers, nanoparticle delivery systems
Sources cited:
Roberti et al., 2019; Villanueva et al., 2020
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Document type:
Supplementary material to a scientific research article
Subject:
Genetic and epigenetic variation in Corydalis yanhusuo populations
Species:
Corydalis yanhusuo
Analytical methods:
STRUCTURE analysis; dbRDA; AFLP; MSAP
Content:
Supplementary figures (S1–S2) and tables (S1–S6)
Populations analyzed:
17 populations (cultivated and natural)
Data included:
Methylation frequencies; primer and adapter sequences; monthly mean weather parameters; pairwise FST values
Genetic markers:
AFLP
Epigenetic markers:
MSAP
Chemical variables:
Tetrahydropalmatine; Protopine; Palmatine; Berberine
Environmental variables:
Air pressure; temperature; relative humidity; precipitation; sunshine duration
Document Type:
Supplemental figure legends
Field:
Molecular biology
Research Area:
Gastrointestinal epithelium and intestinal metaplasia
Subjects:
CDX2, HNF4A, SOX2, gastric organoids, Barrett’s esophagus, gastric intestinal metaplasia
Biological Material:
Human gastrointestinal tissues and mouse stomach organoids
Methods:
Single-cell RNA-seq, bulk RNA-seq, ATAC-seq, CUT&RUN, ChIP-seq, GSEA, enhancer analysis, immunohistochemistry, qRT-PCR
Referenced Studies:
Busslinger et al. 2021b; Nowicki-Osuch et al. 2021; Owen et al. 2018; Companioni et al. 2017; Singh et al. 2021; Gao and Kaestner 2010; Wang et al. 2013
Key Topics:
Transcriptional profiling, chromatin accessibility, enhancer activity, transcription factor binding, intestinalization of gastric epithelium
Species:
Homo sapiens; Mus musculus
Pathological Context:
Barrett’s esophagus; gastric intestinal metaplasia
Year:
2006-2014
Region:
Iowa and North Carolina, USA; Augsburg, Germany
Topic:
Epigenetics, Alcohol consumption, Blood pressure
Document type:
Supplemental materials / Research data description
Institution:
National Institute of Environmental Health Sciences; Cooperative Health Research in the Region Augsburg (KORA)
Authors:
Bui, Keshawarz, Wang et al.
Study design:
Case-control study (ALHS); Population-based cohort (KORA)
Participants:
Farmers and spouses (ALHS); General population aged 25-74 (KORA)
Sample size:
3,301 (ALHS); 1,802 (KORA F4)
Data collected:
DNA methylation, clinical and behavioral phenotypes, alcohol consumption, smoking status
Consent and approval:
Informed consent obtained; Institutional Review Board approval (ALHS)
Funding:
Intramural Research Program of the NIH, National Cancer Institute, American Recovery and Reinvestment Act funds
Analytical methods:
DNA methylation measurement with EPIC and 450K BeadChips, quality control, normalization, cell type estimation, statistical regression analyses
Year:
2024
Region / City:
Bodø, Norway; Edinburgh, Scotland; Barcelona, Spain
Subject:
Reproductive endocrinology, teleost puberty
Document type:
Research article
Institution:
Nord University, The Roslin Institute, Institute of Marine Science (ICM)
Authors:
L. Colonna, I. Konstantinidis, R.R. Daniels, D. Robledo, J.M.O. Fernandes
Target audience:
Researchers in marine biology and fish physiology
Methodology:
Single-cell RNA-seq and ATAC-seq profiling
Model organism:
Nile tilapia (Oreochromis niloticus)
Experimental conditions:
Continuous and ambient light exposure for 4 months
Purpose:
Identification of pituitary cell types and markers associated with puberty onset in teleosts
Reference:
M. Li, L. Sun, L. Zhou & D. Wang (2024). Gen Comp Endocrinol 345:114395
Document type:
Research proposal section
Research area:
Systems biology and epigenetics
Scientific field:
Gene regulatory network modeling
Research focus:
Integration of epigenetic regulators into gene network inference
Model organism:
Arabidopsis thaliana
Key regulator studied:
SET Domain Group 8 (SDG8)
Homologous human protein:
SETD2
Epigenetic mechanism:
H3K36 histone methylation
Biological processes referenced:
Gene regulation and chromatin modification
Methodological approaches:
Time-course transcriptome analysis, predictive network modeling, dynamic Bayesian networks, state-space modeling
Data sources referenced:
Epigenomics datasets and ENCODE resources
Research objectives:
Identification of genomic targets of epigenetic regulators and evaluation of their role as predictors in gene regulatory network models
Proposed framework:
EpiNet
Research components:
Significance, Innovation, and Approaches
Experimental strategy:
Integration of experimental perturbation data with computational network inference
Year:
2025
Region / city:
Sudan
Topic:
Sexual Exploitation and Abuse, Gender-Based Violence, Child Protection
Document Type:
Action Plan
Author:
United Nations Children’s Fund (UNICEF)
Target Audience:
Humanitarian and development actors, implementing partners, organizations involved in child protection and gender-based violence
Period of validity:
March 2025
Approval Date:
March 2025
Date of amendments:
N/A
Context:
This document outlines a detailed action plan to address sexual exploitation and abuse/sexual harassment risks within the context of the Sudan Emergency Crisis Response Safety Net Project (SANAD), focusing on mitigation strategies and survivor support mechanisms.
Year:
2021
Location:
Islamabad, Pakistan
Topic:
Sexual Exploitation and Abuse (SEA) Prevention and Response
Document Type:
Training Agenda
Organization:
National Humanitarian Network (NHN)
Author:
Not specified
Target Audience:
Humanitarian workers and organizations
Duration:
2–3 December 2021
Approval Date:
Not specified
Date of Last Update:
Not specified
Year:
2023
Region / city:
Somalia
Topic:
Sexual Exploitation, Abuse, and Harassment Prevention
Document type:
Action Plan
Organization / institution:
Ministry of Labor & Social Affairs (MOLSA), Federal Government of Somalia
Author:
N/A
Target audience:
Project Implementing Committee, project workers, stakeholders in Somalia
Effective period:
Ongoing, from December 2023
Approval date:
December 2023
Amendment date:
N/A
Note:
Contextual Description
Submitted by:
Migration Youth and Children Platform
Contributors:
Bushra Qayyum (Chair), Anaïs Elbassil, Md Sohanur Rahman, Rochelle Prasad, Rajaa Essaghyry, Larissa Truchan (Facilitator and Editor)
Submission Date:
25 April 2025
Issued by:
Special Rapporteur on the sale and sexual exploitation of children
Organization:
Migration Youth and Children Platform (MYCP)
Type of document:
Written submission
Topic:
Child sexual exploitation, Migration, Street children
Geographical focus:
Global, with specific case study in Islamabad, Pakistan
Target audience:
UN policymakers, law enforcement, child protection actors
Period covered:
2017–2025
Methodology:
Research Task Force consultation with youth constituency members
Case studies included:
Yes, including migrant girls in Islamabad, Pakistan
Year:
2022
Region / City:
United Kingdom
Theme:
Child Exploitation
Document Type:
Risk Assessment Tool
Organ / Institution:
Local Authorities, Child Protection Services
Author:
Not specified
Target Audience:
Professionals working with children, young people, and families
Period of Validity:
Indefinite
Approval Date:
Not specified
Date of Changes:
Not specified
Year:
2008
Region / City:
Global
Theme:
Protection from Sexual Exploitation and Abuse (PSEA)
Document Type:
Policy
Organization / Institution:
United Nations (UN)
Author:
UN System
Target Audience:
UN Personnel, Partners, and Stakeholders
Period of Validity:
Not specified
Approval Date:
Not specified
Date of Amendments:
Not specified
Year:
2015
Region / City:
State of Georgia
Topic:
Child Abuse, Sexual Abuse, Sexual Exploitation
Document Type:
Protocol
Organization / Institution:
Office of the Child Advocate for the Protection of Children
Author:
Jodi Ann Spiegel, J.D., M.S., Deputy Director
Target Audience:
Professionals in child welfare and law enforcement
Period of Validity:
N/A
Approval Date:
October 1, 2015
Date of Changes:
2015 (noted in Blue)
Year:
2023
Region / City:
Kenya
Topic:
Sexual Exploitation and Abuse / Sexual Harassment Prevention
Document Type:
Action Plan
Organization / Institution:
World Bank
Author:
Not specified
Target Audience:
Project stakeholders, implementers, and affected communities
Period of Validity:
Not specified
Approval Date:
August 2023
Date of Amendments:
Not specified
Year:
2023
Region / City:
Bolori, Modusulumri, Gwange
Theme:
Protection from Sexual Exploitation and Abuse
Document Type:
Report
Organization:
Concern for Women and Children Development Foundation
Author:
Unknown
Target Audience:
Affected population (men, women, children, persons with disabilities)
Period of Activity:
Weekly throughout project cycle
Approval Date:
Unknown
Date of Changes:
Unknown
Year:
2022
Region / City:
Kenya
Theme:
Sexual Exploitation, Abuse, and Harassment Prevention
Document Type:
Prevention and Response Plan
Organization:
Ministry of Agriculture, Livestock, Fisheries and Cooperatives
Author:
Ministry of Agriculture, Livestock, Fisheries and Cooperatives
Target Audience:
Project Workers, Stakeholders, and Affected Communities
Implementation Period:
2022 - ongoing
Approval Date:
2nd September 2022
Amendment Date:
N/A
Year:
2021
Location:
Bandung Metropolitan Area, Indonesia
Theme:
Gender-Based Violence, Sexual Exploitation and Abuse, Sexual Harassment
Document type:
Action Plan
Organization:
Ministry of Transport, Government of Indonesia
Author:
World Bank and Ministry of Transport
Target audience:
Project implementers, contractors, consultants, community stakeholders
Period covered:
2020–2024
Project:
Indonesian Mass Transit Program Support Project (IMTPSP)
Appendices included:
List of service providers, Grievance redress mechanism and response protocol, Consent and intake forms, Codes of Conduct, Required clauses for bid documents
Year:
2022
Country:
Ethiopia
City:
Addis Ababa
Type of document:
Action plan
Thematic focus:
Sexual exploitation and abuse, sexual harassment, gender-based violence
Project name:
Response, Recovery and Resilience for Conflict-Affected Communities in Ethiopia (3R-4-CACE)
Project ID:
P177233
Implementing institution:
Ministry of Finance
Geographic scope:
National, with initial focus on Afar, Amhara, Benishangul-Gumuz, Oromia, and Tigray regions
Target groups:
Conflict-affected communities, internally displaced persons, host communities, GBV survivors
Implementation period:
2022–2027
Funding components:
Basic services and infrastructure, GBV response services, project management, contingent emergency response
Source type:
Government policy and project implementation document
Note:
Year
Topic:
Sexual exploitation and abuse prevention
Document Type:
Assessment Tool
Organization / Institution:
International Organization for Migration (IOM)
Target Audience:
IOM implementing partners
Year:
2025
Region / City:
Sefton
Theme:
Child Protection, Exploitation, Safeguarding
Document Type:
Policy and Procedure
Organization / Institution:
Sefton Safeguarding Children Partnership
Author:
Sefton Safeguarding Children Partnership
Target Audience:
Professionals and organizations involved in child safeguarding and protection
Effective Period:
Ongoing
Approval Date:
March 2025
Date of Changes:
N/A
Year:
Not specified
Region / City:
Not specified
Topic:
Child Exploitation
Document Type:
Guidance Notes
Organization / Institution:
Not specified
Author:
Not specified
Target Audience:
Practitioners working with children at risk of child exploitation
Effective Period:
Not specified
Approval Date:
Not specified
Amendment Date:
Not specified