№ files_lp_4_process_2_74884
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Detailed reference for definitions and clinical presentation of infection, sepsis, and wound complications including major and minor surgical site infections, abscesses, and cellulitis, highlighting systemic inflammatory responses and associated treatments.
Year:
2026
Topic:
Infectious diseases, surgical site infections
Document type:
Medical reference / educational material
Target audience:
Healthcare professionals, medical students
Key terms:
Infection, bacteremia, sepsis, severe sepsis, septic shock, abscess, cellulitis, MODS, SIRS
Clinical focus:
Wound infection classification, abscess formation, systemic inflammatory responses
Treatment overview:
Drainage procedures, antibiotic therapy, systemic support
Pathogens mentioned:
Staphylococcus aureus, Gram-negative bacteria (E.coli)
Onset period:
7–10 days post-surgery for wound abscesses
Price: 8 / 10 USD
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The product description is provided for reference. Actual content and formatting may differ slightly.
Year:
2023
Region / City:
Canberra
Theme:
Sepsis management
Document Type:
Guideline
Institution:
Canberra Health Services
Author:
Canberra Health Services Team
Target Audience:
Medical Team members, Registered Nurses and Midwives, Enrolled Nurses, Pharmacists, Allied Health professionals
Period of Validity:
Ongoing
Approval Date:
Not specified
Date of Changes:
Not specified
Note:
Year
Theme:
Medical procedure
Document Type:
Clinical guideline
Organization / Institution:
Canberra Health Services
Target Audience:
Healthcare professionals at North Canberra Hospital
Year:
2023
Region / City:
Warrington
Topic:
Sepsis Screening
Document Type:
Instructional Guide
Organization / Institution:
Warrington Emergency Department
Author:
Not specified
Target Audience:
Healthcare professionals
Action Period:
Not specified
Approval Date:
Not specified
Date of Changes:
Not specified
Year:
2017
Region / City:
Emergency Department
Topic:
Severe Sepsis, Septic Shock, Patient Rescreening
Document Type:
Advisory, Medical Alert
Institution:
UCLA
Author:
Not specified
Target Audience:
Emergency Department Nurses
Action Period:
3/3/17 – proposed changes
Approval Date:
Not specified
Modification Date:
3/24/17
Context:
A guideline for the early identification and rescreening of patients at risk for severe sepsis or septic shock in an emergency department setting, with detailed criteria for triggers and actions.
Year:
2024
Region / City:
Swansea Bay UHB
Subject:
Sepsis Quality Priority
Document Type:
Report
Institution:
Swansea Bay University Health Board
Author:
Dr. Rangaswamy Mothukuri, Lisa Fabb
Target Audience:
Healthcare professionals
Period of Action:
2021-2024
Approval Date:
November 2024
Amendment Date:
N/A
Sponsoring Organization:
Centers for Disease Control and Prevention (CDC)
Implementing Organization:
ICF
Document Type:
Focus Group Moderator’s Guide
Topic:
Sepsis education and health communication materials testing
Target Audience:
Cancer patients and their caregivers
Purpose:
Collection of feedback on sepsis knowledge and evaluation of educational materials
Format:
Structured discussion guide with scripted questions and probes
Estimated Session Duration:
Approximately 60 minutes
Components:
Welcome script, consent procedures, discussion questions, material testing segment
Referenced Material:
“Protect Yourself and Your Family from Sepsis” Fact Sheet
Data Collection Method:
Audio-recorded focus group interview
Confidentiality Provisions:
Removal of identifying information from reports
Year:
2020
Country:
Australia
Region:
Nationwide
Organisation:
Australian Group on Antimicrobial Resistance (AGAR)
Programme:
Australian Gram-negative Sepsis Outcome Programme (GnSOP)
Authors:
Jan M Bell; Alicia Fajardo Lubian; Sally R Partridge; Thomas Gottlieb; Jonathan Iredell; Denise A Daley; Geoffrey W Coombs
Type of document:
Annual surveillance report
Subject:
Antimicrobial resistance in gram-negative bloodstream infections
Pathogens studied:
Enterobacterales; Escherichia coli; Klebsiella pneumoniae; Enterobacter cloacae complex; Pseudomonas aeruginosa; Acinetobacter species
Sample size:
8,752 isolates
Study period:
1 January to 31 December 2020
Participating laboratories:
30 laboratories
Institutions covered:
49 institutions
Methodology:
Automated susceptibility testing; PCR screening; whole genome sequencing
Standards applied:
CLSI M100; EUCAST v11.0 (January 2021)
Key focus:
Resistance to third-generation cephalosporins; fluoroquinolones; piperacillin-tazobactam; carbapenems; colistin
Carbapenemase genes detected:
blaIMP-4; blaGES-5; blaNDM-1; blaNDM-5; blaOXA-48; blaOXA-181; blaIMI-1; blaOXA-23+NDM-1
Year:
2023
Region / city:
Multicenter
Topic:
Sepsis, Procalcitonin kinetics, Mortality prediction
Document type:
Supplemental Content
Organization:
Multiple medical centers
Author:
Not specified
Target audience:
Healthcare professionals, researchers in sepsis
Period of validity:
Not specified
Approval date:
Not specified
Modification date:
Not specified
Year:
2026
Region / City:
United States (National)
Topic:
Health communication, sepsis awareness
Document type:
Focus group moderator guide
Organization:
Centers for Disease Control and Prevention (CDC), ICF
Audience:
Spanish-speaking women
Duration:
75 minutes
Content format:
Discussion guide with sections on welcome, knowledge assessment, and material testing
Materials included:
Animated video “Cuatro Maneras De Ganarle a la Septicemia”
Purpose:
Collect participant feedback on health communication materials and sepsis awareness
Document type:
Supplementary research tables and figure
Field of study:
Infectious diseases and clinical epidemiology
Topic:
Sepsis onset timing, bloodstream pathogens, and statistical analysis of clinical variables
Related condition:
Sepsis during the CIN window
Data scope:
Distribution of sepsis onset times from index time (T0; first CIN onset)
Sample size (sepsis cases):
48
Blood culture isolates analyzed:
31
Pathogen categories:
Gram-negative bacteria, Gram-positive bacteria, fungi
Key pathogens listed:
Escherichia coli; Pseudomonas aeruginosa; Viridans streptococci; Enterococcus spp; Staphylococcus aureus; Candida albicans
Statistical analysis:
Variance Inflation Factor (VIF) analysis after excluding CRP
Variables analyzed:
CAR, RDW, PLT, PCT, IL6, Oral mucosal status, Risk stratification
Figure description:
Missing data assessment for variables included in the analyses
Abbreviations defined:
CAR (C-reactive protein/albumin ratio); PCT (procalcitonin); RDW (red blood cell distribution width); PLT (platelet)
Year:
2015
Region / city:
Global
Topic:
Infectious diseases, sepsis, viral and bacterial co-infections
Document type:
Scientific article
Organization / institution:
Various medical institutions and researchers
Author:
Multiple authors
Target audience:
Medical professionals, researchers in infectious diseases
Effective period:
N/A
Approval date:
2015
Modification date:
N/A
Study period:
3 years
Location:
United Kingdom
Target group:
Adults admitted to ICU with sepsis
Study type:
Clinical research trial
Interventions:
PCR diagnostic testing, fluid management trial, GM-CSF treatment trial
Number of participants:
Up to 3800 patients
Purpose:
To evaluate optimal treatments for sepsis
Sponsor:
Not specified
Consent required:
Yes
Follow-up:
3 and 6 months post-enrollment
Intervention:
Arthroscopic hip surgery
Conditions treated:
Labral tear; Femoro-Acetabular Impingement (FAI); Sepsis of the hip joint; Loose body
Document type:
Commissioning policy / clinical commissioning position
Subject area:
Orthopaedic surgery; hip joint disorders
Clinical indications:
Labral tear; Femoro-Acetabular Impingement Syndrome; septic arthritis of the native hip joint; intra-articular loose bodies following trauma
Eligibility criteria:
Defined clinical, radiological, symptomatic, and treatment history requirements including failure of conservative therapy
Target patient group:
Adults aged 18–50 years for FAI-related surgery
Authoring body:
NICE referenced; British Hip Society referenced
Register requirement:
Non-Arthroplasty Hip Surgery Register maintained by the British Hip Society
Evidence basis:
Clinical and radiological diagnosis including X-ray, MRI, and CT
Effective from:
October 2024
Policy review date:
October 2027
References:
NICE IPG408 guidance; British Orthopaedic Association guidance on hip pain in adults; British Hip Society Non-Arthroplasty Hip Registry; SANJO guideline for septic arthritis; Journal of Orthopaedic Trauma article on arthroscopic removal of loose bodies
Research Field:
Immunology
Subfield:
Host Defense and Sepsis
Experimental Model:
C57BL/6 and C57BL/6J mice
Biological Focus:
Macrophage function and bacterial clearance
Bacterial Species:
Pseudomonas aeruginosa
Laboratory Techniques:
CFU determination, ELISA, flow cytometry, Western blot, siRNA interference, fluorescence microscopy
Cell Type:
Mouse peritoneal macrophages (PMφs)
Tissues Examined:
Lung, liver, spleen, kidney
Biochemical Markers:
ALT, AST, LDH, creatinine
Cytokines and Chemokines Measured:
Prokineticin-2, TNF-α, IL-6, IL-10, IL-17A
Experimental Interventions:
rPK2 stimulation, PKR1/PKR2 siRNA transfection, macrophage depletion with clodronate liposomes
Time Points of Analysis:
24 hours and 48 hours after modeling
Detection Methods:
Hematoxylin-eosin staining, fluorescence microscopy, FACScan flow cytometry, ELISA assays
Software for Analysis:
FCM Express
Referenced Studies:
Song et al., 2016; Song et al., 2015
Animal Age:
Six- to eight-week-old mice
Year:
2023
Field:
Medicine / Critical Care Medicine / Infectious Diseases
Topic:
Corticosteroid therapy in sepsis and septic shock
Document type:
Supplementary appendix to a systematic review and meta-analysis
Methodology:
Systematic review, pairwise meta-analysis, dose-response meta-analysis
Guideline framework:
PRISMA-S, GRADE
Population studied:
People with sepsis, severe sepsis, or septic shock
Interventions analyzed:
Corticosteroids including hydrocortisone, dexamethasone, methylprednisolone, prednisolone, prednisone, cortisone, betamethasone, and fludrocortisone
Comparators:
Placebo or no corticosteroid treatment
Outcomes assessed:
Short-term mortality, long-term mortality (90–180 days), shock reversal, organ dysfunction, ICU length of stay, hospital length of stay, adverse events, quality of life
Data sources:
MEDLINE, Embase, LILACS, Cochrane Clinical Trials Register
Study design included:
Randomized controlled trials
Search date:
October 12, 2022
Literature update date:
January 10, 2023
Publication limits:
Human studies; publication year ≥ 2018
Key analytical components:
Hydrocortisone dose equivalence conversion, mineralocorticoid activity index, certainty of evidence assessment
Supplement contents:
Search strategies, trial characteristics tables, risk of bias assessments, certainty of evidence tables, PRISMA diagram, outcome figures and subgroup analyses
Year:
2012
Region / city:
United Kingdom
Topic:
Tattooing, Body Art, Health Risks, Epidemiology, Guidelines
Document type:
Literature Review
Organization / institution:
Health Protection Agency, Chartered Institute of Environmental Health, Tattoo and Piercing Industry Union
Author:
Dr. Victor Aiyedun
Target audience:
Health professionals, regulators, practitioners
Period of validity:
Not specified
Approval date:
Not specified
Date of last modification:
Not specified
Note:
Year
Topic:
Endocrine hypertension, primary aldosteronism
Document type:
Position statement
Organization / institution:
European Society of Hypertension, Japan Endocrine Society, Taiwan Society of Aldosteronism
Author:
Paolo Mulatero, Leonardo Sechi, Tracy Ann Williams, Jacques W.M. Lenders, Martin Reincke, Fumitoshi Satoh, Andrzej Januszewicz, Mitsuhide Naruse, Michael Doumas, Franco Veglio, Vin Cent Wu, Jiri Widimsky
Target audience:
Healthcare professionals, researchers in endocrinology and hypertension
Year:
1986–2023
Type:
Literature review / reference compilation
Topic:
Central venous catheterization, mechanical complications, training, ultrasound guidance
Authors:
Walsh EC, Fitzsimons MG, Gibson F, Bodenham A, Bannon M, Heller, Rivera, Adrian M, Borgquist O, Kröger T, Domino KB, Lee LA, Sznajder JI, Zveibil FR, Bitterman H, Weiner P, Bursztein S, Barsuk JH, Cohen ER, Feinglass J, McGaghie WC, Wayne DB, Moureau N, Lamperti M, Kelly LJ, Koh J, Xu Y, Yeo L, Soffler MI, Hayes MM, Smith CC, Peltan ID, Shiga T, Gordon JA, Currier PF, Ma IWY, Brindle ME, Ronksley PE, Lorenzetti DL, Sauve RS, Ghali WA, Duncan JR, Henderson K, Street M, McGee DC, Schummer W, Schummer C, Rose N, Niesen WD, Sakka SG, Milling TJ, Rose J, Briggs WM, Troianos CA, Jobes DR, Ellison N, Leung J, Duffy M, Finckh A, Bansal R, Agarwal SK, Tiwari SC, Dash SC, Mallory DL, McGee WT, Shawker TH, Brass P, Hellmich M, Kolodziej L, Schick G, Gualtieri E, Deppe SA, Sipperly ME, Thompson DR, Fragou M, Gravvanis A, Dimitriou V, Aouad MT, Kanazi GE, Abdallah FW, Ablordeppey EA, Drewry AM, Beyer AB, Bodenham Chair A, Babu S, Bennett J, Parienti JJ, Mongardon N, Mégarbane B, Mira JP, Kalfon P, Gros A, Marqué S, Thuong M, Pottier V, Ramakers M, Savary B, Seguin A, Valette X, Terzi N, Sauneuf B, Cattoir V, Mermel LA, du Cheyron D, Chen HE, Sonntag CC, Pepley DF, Prabhu RS, Han DC, Moore JZ, Miller SR, Yovanoff MA, Mirkin KA, Mohamadipanah H, Parthiban C, Nathwani J, Rutherford D, DiMarco S, Pugh C, Clinkard D, Holden M, Ungi T, Messenger D, Davison C, Fichtinger G, McGraw R
Source type:
Scientific journal articles
Period covered:
1986–2023
Medical field:
Anesthesiology, intensive care, surgery
Focus:
Mechanical complications, central venous catheter placement, procedural training, simulation, ultrasound guidance
Year:
2018-2019
Region / City:
Beirut, Lebanon
Topic:
Obesity, Type 2 Diabetes, Cardiometabolic Risk Factors
Document Type:
Research Article
Institution:
Hôtel-Dieu de France Hospital, Faculty of Medicine, Saint-Joseph University
Authors:
Isabelle Jambart, Ghassan Sleilaty, Sélim Jambart, Rita Medlej, Georges Halaby, Chawki Atallah, Marie-Hélène Gannagé-Yared, Georges Hajje
Target Audience:
Healthcare professionals, researchers
Study Period:
December 2018 - December 2019
Approval Date:
Not specified
Date of Changes:
Not specified
Note:
Year
Topic:
Medical Diagnosis and Documentation
Document Type:
Clinical Guidelines
Target Audience:
Healthcare Professionals