№ files_lp_3_process_7_041572
Supplementary statistical tables presenting the protocol specification of a target trial and its emulation using observational data, alongside baseline characteristics of adults with Type 2 diabetes stratified by HbA1c levels and monitoring intervals.
Year: 2009–2021
Population: Adult patients with Type 2 diabetes
Study period: 1 Jan 2009 – 31 Dec 2021
Exposure: HbA1c monitoring frequency
Stratification: Baseline HbA1c levels (<7%, 7–7.9%, 8–8.9%, ≥9%)
Primary outcome: All-cause mortality
Secondary outcomes: Major cardiovascular diseases, myocardial infarction, stroke, congestive heart failure
Design: Target trial specification and observational emulation
Data source: Observational healthcare records
Sample size: 82,679 participants (HbA1c <7% group)
Analytical approach: Cloning, censoring, and weighting
Follow-up: From baseline to outcome, death, or 31 Dec 2021
Baseline variables: Age, sex, Charlson Comorbidity Index, smoking status, comorbidities, medication use
Medication categories: Anti-hypertensive drugs, oral antidiabetic drugs, sulfonylureas, metformin, DPP-4 inhibitors, GLP-1 receptor agonists, SGLT2 inhibitors, insulins
Price: 8 / 10 USD
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