№ files_lp_3_process_7_073822
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Formulaire destiné aux chercheurs pour demander un devis détaillé pour la synthèse, la modification et la purification de mRNA in vitro selon des spécifications précises.
Year:
2026
Region / City:
International
Subject:
mRNA synthesis and customization
Document Type:
Quotation Request Form
Organization:
Blue Heron Biotech
Target Audience:
Researchers and biotech companies
Required Materials:
DNA template ≥ 20 µg
Template Options:
Circular plasmid or PCR product
Promoter Options:
T7 promoter included or to be added
UTR Options:
5’ and 3’ UTR sequences provided or selected
Modifications:
Pseudouridine, N1-me-pseudouridine, 5-methoxyuridine, 5-me-Cytidine
Purification Methods:
Silica membrane-based or alternative
mRNA Scale Options:
100 µg, 150 µg, 200 µg
QC Tests:
Visual appearance, nanodrop concentration, PAGE/agarose integrity, pH, optional capping efficiency, CE-based size and integrity, endotoxin test
Storage Buffer Options:
Nuclease-free water, 1mM Sodium citrate pH 6.4
Price: 8 / 10 USD
The file will be delivered to the email address provided at checkout within 12 hours.
The file will be delivered to the email address provided at checkout within 12 hours.
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The product description is provided for reference. Actual content and formatting may differ slightly.
Year:
2026
Region / City:
Not specified
Topic:
BDNF expression analysis
Document Type:
Research data
Organization / Institution:
Not specified
Author:
Not specified
Target Audience:
Researchers in molecular biology and neuroscience
Period of validity:
Not specified
Approval Date:
Not specified
Date of Changes:
Not specified
Year:
2025
Region / city:
United Kingdom
Subject:
COVID-19 vaccination
Document type:
Protocol
Institution:
UK Health Security Agency (UKHSA)
Author:
UK Health Security Agency (UKHSA)
Target audience:
Healthcare providers involved in COVID-19 vaccination
Period of validity:
1 October 2025 – 31 January 2026
Approval date:
12 September 2025
Note:
Revision history
Year:
Not specified
Species:
Piglet
Tissue:
Hippocampus
Gene:
BDNF
Reference gene:
RO
Method:
RT-qPCR
Data type:
Raw quantitative PCR data
Experimental groups:
Control, 18 µg/kg, 46 µg/kg
Measurements:
CT, ΔCT, ΔΔCT, 2^-ΔΔCT, 2^-ΔCT
Statistical parameters:
Average, STDEV
Sample identifiers:
Sample 1–Sample 50
Document type:
Supplementary data table
Reference no:
COVID-19 mRNA vaccine (5 years and over) PGD
Version no:
v3.0
Valid from:
1 October 2025
Expiry date:
31 January 2026
Developed by:
UKHSA
Healthcare practitioners:
Registered healthcare practitioners identified in section 3
Amendment history:
Updated in versions v1.0, v2.0, and v3.0
Target group:
Eligible individuals aged 5 years and over
Immunisation programme:
National COVID-19 vaccination programme
Eligibility criteria:
Based on age and health conditions
Training requirements:
Compliance with national vaccination training standards
Review panel:
UKHSA Immunisations PGD Expert Panel
Expert authors:
Pharmacist Christina Wilson, Dr Alex Allen, Nurse David Green
NHS England responsibility:
Governance and authorisation
Period of retention:
25 years for NHS England, 8–25 years for providers
NHS England governance:
NHS England accepts responsibility for PGD governance
Year:
2025
Region / City:
Northern Ireland
Topic:
COVID-19 vaccination, mRNA vaccines
Document Type:
Protocol
Organization / Institution:
Strategic Planning and Performance Group (SPPG), Public Health Agency (PHA)
Author:
Dr. Louise Herron, Mrs. Deirdre Ward, Mrs. Kathryn Turner
Target Audience:
Healthcare professionals administering COVID-19 mRNA vaccines
Period of Validity:
3 April 2025 to 30 June 2025
Approval Date:
3 April 2025
Note:
Change History
Version 1.0:
New national protocol for COVID-19 vaccines (adults) - 5 April 2024
Version 2.0:
Updated to reflect change in vaccine antigenic content - 16 September 2024
Version 3.0:
Updated eligibility criteria for Spring 2025 - 6 March 2025
Year:
2025
Region / city:
United Kingdom
Subject:
COVID-19 vaccination
Document type:
Protocol
Organization / institution:
UK Health Security Agency (UKHSA)
Author:
UK Health Security Agency (UKHSA)
Target audience:
Healthcare professionals involved in COVID-19 vaccination
Effective period:
From 1 October 2025 to 31 January 2026
Approval date:
12 September 2025
Note:
Amendment history
v1.0:
6 September 2024
v2.0:
18 February 2025
v3.0:
29 August 2025
Description:
Protocol for the administration of COVID-19 mRNA vaccine to individuals aged 5 years and over, detailing eligibility, vaccine preparation, and staff requirements.
Note:
Year
Authors:
Cassandra M. Juran; Justina Zvirblyte; Yasaman Sharazi; Angela Kubik; Margareth Cheng-Campbell; Elizabeth Blaber; Eduardo Almeida
Affiliations:
Blue Marble Space Institute of Science at NASA Ames Research Center, Mountain View, CA, USA; Vilnius University, Vilnius, Lithuania; Rensselaer Polytechnic Institute, Troy, NY, USA; NASA Ames Research Center, Moffett Field, CA, USA
Research Field:
Stem cell biology; Bone regeneration; Mechanobiology; Space biology
Key Gene:
CDKN1A (Cdkn1a)
Experimental Models:
Wildtype and Cdkn1a-null mice
Methods:
Single-cell mRNA sequencing; in-vitro mechanical stretch; hindlimb unloading; running wheel and treadmill loading; spaceflight microgravity exposure
Space Mission:
Rodent Research-10 aboard the International Space Station
Duration of Spaceflight:
30 days
Biological Material:
Femur bone marrow; mesenchymal osteoprogenitors; osteoblast lineage cells
Type of Document:
Scientific research article
Institutional Context:
NASA-affiliated and academic biomedical research collaboration
Year:
2023
Region / City:
Not specified
Topic:
m6A methylation, NLRP3 mRNA
Document Type:
Research Supplementary Table
Institution:
Not specified
Author:
Not specified
Target Audience:
Researchers in molecular biology and genetics
Period of Action:
Not specified
Approval Date:
Not specified
Modification Date:
Not specified
Authors:
Tony Malmqvist; Karen Anthony; Jean-Marc Gallo
Affiliation:
Department of Clinical Neuroscience, King’s College London, Institute of Psychiatry, London, United Kingdom
Corresponding Author:
Jean-Marc Gallo
Institutional Address:
King’s College London, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, United Kingdom
Type of Document:
Scientific research article
Field of Study:
Neuroscience; Molecular and Cellular Biology
Research Subject:
Localization and translation of tau mRNA in rat cortical neurons
Biological Material:
Primary rat cortical neurons
Key Methods:
Fluorescence in situ hybridization (FISH); RNA staining; immunocytochemistry
Key Molecules:
Tau mRNA; eukaryotic elongation factor 1A (eEF1A); neurofilament heavy subunit (NF-H)
Geographical Context:
London, United Kingdom
Institutional Context:
King’s College London, Institute of Psychiatry
Language:
English
Year:
2026
Region / Institution:
Not specified
Topic:
Immunology, SARS-CoV-2, Vaccine Response
Document type:
Peer Review
Author:
Stefania P Bjarnarson
Target audience:
Researchers, Immunologists
Study period:
Up to 33 months post mRNA vaccination
Methods:
Analysis of bone marrow plasma cells, healthy adult donors, post-vaccination sampling
Key findings:
Limited presence of SARS-CoV-2-specific long-lived plasma cells in bone marrow after mRNA vaccination or hybrid immunity
Data source:
Bone marrow aspirates, hip joint replacement surgery samples
Limitations:
Small sample size, discrepancies in patient description, consideration of asymptomatic infections
Scientific relevance:
Provides evidence on the longevity of humoral immune response post-vaccination
Concise description:
Peer-reviewed evaluation of a study assessing the presence of SARS-CoV-2-specific long-lived plasma cells in the bone marrow following mRNA vaccination and hybrid immunity, highlighting methodology, key results, and points for revision.
Year:
2016
Region / city:
Not specified
Topic:
Methods
Document type:
Research Methodology
Organization:
Not specified
Author:
Not specified
Target audience:
Researchers in the field of molecular biology
Period of validity:
Not specified
Date of approval:
Not specified
Date of modification:
Not specified
Year:
2021
Region / city:
Australia
Theme:
Medical Research, mRNA Clinical Trials
Document Type:
Grant Application Guidelines
Organization / Institution:
Department of Industry, Science, Energy and Resources
Author:
Department of Industry, Science, Energy and Resources
Target Audience:
Researchers, Institutions, Organizations applying for MRFF grants
Period of Validity:
2021-2022
Approval Date:
December 2021
Amendment Date:
None
Program:
MRFF – 2021 mRNA Clinical Trial Enabling Infrastructure
Eligibility Criteria:
State government partner required, Organization must be incorporated in Australia, Entity type selection
Required Documents:
Financial details, ABN, Program selection
Supported Browsers:
Mozilla Firefox, Google Chrome, Microsoft Edge (Windows), Safari, Google Chrome (Mac)
Description:
Online application form for the MRFF 2021 mRNA Clinical Trial Enabling Infrastructure grant opportunity outlining instructions and eligibility criteria for applicants.
Year:
2016–2021
Field:
Cancer Genomics
Research Topic:
Lung Adenocarcinoma (LUAD) Molecular Subtypes
Document Type:
Supplementary Scientific Notes and Figures
Study Context:
Comparative analysis with Chen et al. 2016 study and related genomic datasets
Data Sources:
TCGA LUAD cohort; CCLE LUAD cell lines; CPTAC LUAD cohort
Analytical Methods:
mRNA expression clustering; GSVA pathway analysis; MutSig2CV mutation analysis; GISTIC2.0 copy number analysis; Cox proportional hazards modeling
Key Molecular Features:
STK11/KRAS co-mutation; MET activation; stem cell gene signature
Subtype Classification:
Five LUAD mRNA expression subtypes (S1–S5)
Comparative Subtypes Referenced:
PP, PI, TRU expression-based subtypes
Genomic Data Types:
DNA copy number; DNA methylation; mRNA expression; miRNA expression; protein expression
Immune Phenotyping Source:
TCGA H&E image–based immune scores
Gene Signature Components:
C6orf62; DNER; NELL2; LATS2; LGR5; PTPRO; LRIG1; PABPC1; NT5E; SET
Referenced Studies:
Chen et al., 2016; Huang et al., 2021; Thorsson et al., 2018
Year:
2017
Organization:
United Nations Development Programme (UNDP)
Location:
Belgrade, Serbia
Type of document:
Request for Quotation (RFQ)
Subject:
Translation services for multiple languages including English, Macedonian, BCMS, Romanian, and Russian
Deadline for Submission:
23 March 2017, 17:00 CET
Contract Type:
Long-Term Agreement (LTA) with possibility of extension
Currency:
USD
VAT:
Excluded
Required Documentation:
Company profile, quality certificates, self-declaration, financial statements, CVs and diplomas of translators, methodology for quality assurance
Experience Requirements:
Translators minimum 6 years, quality assurance translators minimum 8 years
Period of Quote Validity:
60 days
Partial Quotes:
Permitted for specified LOTs
Payment Terms:
Within 30 days after approval of completed translation work
Year:
2025
Region / City:
Pretoria, South Africa
Topic:
Procurement
Document Type:
Request for Quotation
Organization / Institution:
Agricultural Research Council
Author:
Rirhandzu Hlatshwayo
Target Audience:
Bidders, Suppliers
Period of Validity:
Until 05-09-2025
Date of Approval:
05-09-2025
Date of Changes:
N/A
Year:
2022
Region / City:
Coquitlam
Topic:
Request for Quotation
Document Type:
Form
Author:
City of Coquitlam
Target Audience:
Potential contractors and vendors
Period of Validity:
Until award of contract
Approval Date:
August 18, 2022
Date of Changes:
N/A
Year:
2025
Region / city:
Onderstepoort
Subject:
Goods and Services Procurement
Document Type:
Request for Quotation
Organization / Institution:
Onderstepoort Biological Products Ltd
Author:
Supply Chain Department
Target Audience:
Suppliers
Effective Period:
Until the awarding of the contract
Approval Date:
Aug 07, 2025
Date of Amendments:
Not specified
RFQ Number:
10340353
Bid Number:
10340353
Description:
Supply and delivery of battery
Type of document:
Request for Quotation
Issuing organization:
Passenger Rail Agency of South Africa (PRASA)
Section:
SBD1
Closing date:
21 February 2024
Closing time:
12H00
Currency:
South African Rand
Applicable legislation:
Preferential Procurement Policy Framework Act, 2000; Preferential Procurement Regulations, 2022
Tax authority referenced:
South African Revenue Service (SARS)
Submission location:
Cape Town
Contact person:
Rosinah Skisazana
Contact email:
[email protected]
Contact telephone:
021 449 2095
Procurement category:
Supply of goods
Geographical scope:
Republic of South Africa