№ files_lp_3_process_7_018325
File format: docx Character count: 2708 File size: 16 KB
Scientific research article presenting single-cell transcriptomic analysis of mouse bone marrow under mechanical loading and microgravity conditions to examine CDKN1A-dependent regulation of regenerative osteogenesis.
Authors: Cassandra M. Juran; Justina Zvirblyte; Yasaman Sharazi; Angela Kubik; Margareth Cheng-Campbell; Elizabeth Blaber; Eduardo Almeida
Affiliations: Blue Marble Space Institute of Science at NASA Ames Research Center, Mountain View, CA, USA; Vilnius University, Vilnius, Lithuania; Rensselaer Polytechnic Institute, Troy, NY, USA; NASA Ames Research Center, Moffett Field, CA, USA
Research Field: Stem cell biology; Bone regeneration; Mechanobiology; Space biology
Key Gene: CDKN1A (Cdkn1a)
Experimental Models: Wildtype and Cdkn1a-null mice
Methods: Single-cell mRNA sequencing; in-vitro mechanical stretch; hindlimb unloading; running wheel and treadmill loading; spaceflight microgravity exposure
Space Mission: Rodent Research-10 aboard the International Space Station
Duration of Spaceflight: 30 days
Biological Material: Femur bone marrow; mesenchymal osteoprogenitors; osteoblast lineage cells
Type of Document: Scientific research article
Institutional Context: NASA-affiliated and academic biomedical research collaboration
Price: 8 / 10 USD
The file will be delivered to the email address provided at checkout within 12 hours.

Don’t have cryptocurrency yet?

You can still complete your purchase in a few minutes:
  1. Buy Crypto in a trusted app (Coinbase, Kraken, Cash App or any similar service).
  2. In the app, tap Send.
  3. Select network, paste our wallet address.
  4. Send the exact amount shown above.
After sending, paste your TXID (transaction ID) and your email to receive the download link. Need help? Contact support and we’ll guide you step by step.

The final amount may vary slightly depending on the payment method.
The file will be sent to the email address provided at checkout within 24 hours.
The product description is provided for reference. Actual content and formatting may differ slightly.
Distinct Salmonella Enteritidis lineages associated with enterocolitis in high-income and invasive disease in low-income settings
Year: 2026
Region / countries studied: Global, with focus on high-income countries and sub-Saharan Africa
Subject: Salmonella Enteritidis epidemiology and genomics
Document type: Research article
Institutions: Liverpool School of Tropical Medicine; Wellcome Trust Sanger Institute; Malawi Liverpool Wellcome Trust Clinical Research Programme; multiple international collaborators
Authors: Nicholas A. Feasey, James Hadfield, Karen H. Keddy, Timothy J. Dallman, Jan Jacobs, Xiangyu Deng, Paul Wigley, Lars Barquist, Gemma C. Langridge, Theresa Feltwell, Simon R. Harris, Alison E. Mather, Maria Fookes, Martin Aslett, Chisomo Msefula, Samuel Kariuki, Calman Maclennan, Robert S. Onsare, François X. Weill, Simon Le Hello, Anthony M. Smith, Michael McClelland, Prereak Desai, Christopher M. Parry, John Cheesbrough, Neil French, Josefina Campos, Jose A. Chabalgoity, Laura Betancor, Katie L. Hopkins, Satheesh Nair, Tom J. Humphrey, Octavie Lunguya, Tristan A. Cogan, Milagritos Tapia, Samba Sow, Sharon M. Tennant, Kristin Bornstein, Myron M. Levine, Lizeth Lacharme-Lora, Dean B. Everett, Robert A. Kingsley, Julian Parkhill, Robert S. Heyderman, Gordon Dougan, Melita A Gordon, Nicholas R. Thomson
Keywords: Salmonella Enteritidis, global, multidrug resistant, bacteraemia, gastroenteritis, whole-genome sequencing
Target audience: Epidemiologists, microbiologists, public health researchers
Study period: Multiple isolates collected across 45 countries (specific years not stated)
Methods: Whole-genome sequencing analysis of 675 S. Enteritidis isolates
Findings: Identification of a global epidemic clade and two geographically restricted African clades with genomic degradation and multidrug resistance
Topics: CDKN1A-Dependent Lineages Osteogenesis