№ lp_1_2_10465
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Quantitative experimental dataset presenting raw RT-qPCR measurements of BDNF mRNA levels in piglet hippocampal samples across control and dose-defined experimental groups.
Year: Not specified
Species: Piglet
Tissue: Hippocampus
Gene: BDNF
Reference gene: RO
Method: RT-qPCR
Data type: Raw quantitative PCR data
Experimental groups: Control, 18 µg/kg, 46 µg/kg
Measurements: CT, ΔCT, ΔΔCT, 2^-ΔΔCT, 2^-ΔCT
Statistical parameters: Average, STDEV
Sample identifiers: Sample 1–Sample 50
Document type: Supplementary data table
Price: 8 / 10 USD
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Surgery-induced cell death and gene expression changes in the developing piglet brain compared with anesthesia alone
Year: 2026
Region / City: London, UK and Paris, France
Topic: Neuroscience / Pediatric Anesthesia
Document type: Research article
Institutions: University College London, Kings College London, Inserm U1141, University Paris Diderot, University of Wisconsin-Madison
Authors: Kevin D. Broad, Go Kawano, Igor Fierens, Eridan Rocha-Ferreira, Mariya Hristova, Mojgan Ezzati, Jamshid Rostrami, Daniel Alonso-Alconada, Badr Chaban, Jane Hassell, Bobbi Fleiss, Pierre Gressens, Robert D. Sanders, Nicola J. Robertson
Target audience: Neuroscientists, anesthesiologists, pediatric researchers
Study period: Experimental procedures conducted on neonatal piglets
Approval and ethics: UK Home Office and UCL Ethics Board approval under Animal (Scientific Procedures) Act 1986 and EEC directive 86/609/EEC
Methods: Comparative analysis of anesthesia alone versus anesthesia plus minor surgery; cell death quantified by TUNEL assay; gene expression analyzed via RNAseq
Key terms: Isoflurane, anesthetic toxicity, apoptosis, inflammation, endothelial function, neural plasticity, GABA-A, surgery
Rawdata RT-qPCR mRNA BDNF Cortex
Year: 2026
Region / City: Not specified
Topic: BDNF expression analysis
Document Type: Research data
Organization / Institution: Not specified
Author: Not specified
Target Audience: Researchers in molecular biology and neuroscience
Period of validity: Not specified
Approval Date: Not specified
Date of Changes: Not specified
BDNF: The link between beta-amyloid and memory loss
Year: 2026
Region / City: Hamilton, Ontario, Canada
Topic: Alzheimer’s disease and neurodegeneration
Document type: Scientific article
Institution: McMaster University, Department of Psychiatry and Behavioural Neurosciences
Author: Margaret Fahnestock, PhD
Target audience: Researchers and clinicians in neuroscience and psychiatry
Keywords: BDNF, amyloid-beta, Alzheimer’s disease, cognitive impairment, CREB, neurotrophin
Abbreviations: Aβ, AD, APP, BDNF, CREB, ELISA, FAD, MCI
Research methods: Literature review, analysis of human and transgenic mouse data
Key findings: BDNF down-regulation by soluble amyloid-beta, role of CREB in BDNF expression, mechanisms of synaptic loss and tau pathology
End of study focus: Molecular pathways linking amyloid-beta to cognitive decline in Alzheimer’s disease
Summary type: Academic review
Topics: hippocampus piglet BDNF