№ lp_2_3_41988
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Scholarly research article in microbiology presenting experimental and molecular analyses of Newcastle Disease outbreaks and related pathogen studies in animals, including gene expression profiling, pathogenicity assessment, and histopathological evaluation.
Article Category:
Original Article
Section Category:
Microbiology
Title:
Critical pathways of osteoclast development
Running title:
Not specified
Authors:
John Doe; Honglong Liu; Jeong-Hyun Kim
Affiliations:
Department of Pathobiology, Auburn University Research Initiative in Cancer, College of Veterinary Medicine, Auburn University, Auburn, AL, USA; Safety Assessment Department, China Institute of Veterinary Drug Control, Beijing, China; Department of Veterinary Pharmacology and Research Center and Research Institute of Veterinary Science, College of Veterinary Medicine, Seoul National University, Seoul, Korea
Corresponding author:
Jeong-Hyun Kim
Corresponding author email:
[email protected]
ORCID:
Provided for all authors
Equal contribution:
John Doe and Honglong Liu
Conflict of Interest:
The authors declare no conflicts of interest
Funding:
Ministry of Education (2000R1A6A1A00000)
Data availability:
Available from the corresponding author upon reasonable request
Ethics approval:
Institutional Animal Care and Use Committee of OOOO (Approved number: 2023-0001)
Keywords:
A; B; C; D; E
Study subjects:
Wild Eurasian collared doves; experimental mice; pigs
Geographic reference:
Konarak
Main topics:
Newcastle Disease; osteoclast development; Brucella proteins; pathogen load analysis; differential gene expression
Methods:
RT-PCR; absolute quantitative RT-PCR; RNA extraction; embryo candling; cDNA library sequencing; regression and subgroup analysis
Tables:
Validation of selected DEGs by qRT-PCR; Demographic characteristics and clinical chemistry data
Figures:
Histopathology of small intestine lesions; phylogenetic relationships of the HN gene
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Year:
2021
Region / City:
Slough, UK
Topic:
Immunology, Dermatology
Document Type:
Research Article
Organization / Institution:
UCB
Author:
Joseph Rastrick, Hannah Edwards, Alex S. Ferecskó, Gaëlle Le Friec, Avneet Manghera, Matthew Page, Stevan Shaw
Target Audience:
Researchers, Healthcare Professionals
Period of Validity:
Not specified
Date of Approval:
Not specified
Date of Changes:
Not specified
Context:
The document is a research article presenting findings on the roles of IL-17A and IL-17F in hidradenitis suppurativa (HS), based on human in vitro and clinical experiments.
Year:
2024
Region / city:
N/A
Document type:
Review article
Organization / institution:
N/A
Author:
N/A
Target audience:
Researchers, scientists in neurobiology, biochemistry, and Parkinson’s disease studies
Period of action:
N/A
Approval date:
N/A
Modification date:
N/A
Journal:
World Journal of Gastroenterology
Manuscript Number:
5269
Authors:
Mohammad Irshad, Dhananjay Singh Mankotia, Khushboo Irshad
Affiliation:
All India Institute of Medical Sciences, New Delhi, India
Received:
August 26, 2013
Revised:
September 11, 2013
Accepted:
October 13, 2013
Published online:
2013
Keywords:
Hepatitis C virus, Diagnosis, Pathogenesis, Immunity, Steatosis
Type of document:
Review article
Focus:
HCV infection diagnosis and pathogenesis
Target audience:
Medical researchers, clinicians, and healthcare professionals
Year:
1990s
Region / City:
Australia, Malaysia, Bangladesh, India, Philippines, Singapore
Topic:
Zoonotic diseases, virus transmission, animal infections
Document type:
Scientific Research
Author:
Not specified
Target audience:
Researchers, Public health professionals
Period of validity:
Ongoing
Date of approval:
Not specified
Date of changes:
Not specified
Year:
Not specified
Region / Country:
Not specified
Academic Field:
Virology
Topic:
Human herpes viruses and associated diseases
Document Type:
Lecture notes
Institution / Organization:
Not specified
Author:
Not specified
Target Audience:
Medical or microbiology students
Viruses Discussed:
Herpes simplex virus type 1 (HSV-1), Herpes simplex virus type 2 (HSV-2), Varicella-Zoster virus (VZV), Cytomegalovirus (CMV), Epstein-Barr virus (EBV), Human herpesvirus 6 (HHV-6), Human herpesvirus 7 (HHV-7), Human herpesvirus 8 (HHV-8)
Subfamilies:
Alpha Herpesvirinae, Beta Herpesvirinae, Gamma Herpesvirinae
Genome Type:
Double-stranded DNA (dsDNA)
Virion Structure:
Core, Capsid, Tegument, Envelope
Transmission Routes:
Direct contact, respiratory droplets, sexual transmission, perinatal transmission
Diseases Mentioned:
Herpes simplex infection, Varicella (chickenpox), Herpes zoster (shingles)
Diagnostic Methods:
Giemsa staining, electron microscopy, immunofluorescence, PCR, virus isolation, serology (ELISA, IF)
Key Biological Feature:
Lifelong latency with periodic reactivation
Year:
2026
Journal:
Journal of Medicine and Health Research
Manuscript Number:
Ms_JOMAHR_14356
Type of Article:
Review Article
Author:
Not specified
Reviewer:
Yerko Petar Ivanovic-Barbeito
Affiliation:
Tallaght University Hospital, Ireland
Target Audience:
Pediatricians, infectious disease physicians, neurologists, global health practitioners
Timeframe Covered:
2000–2025
Language:
English
Ethical Considerations:
No human subjects involved
Year:
2010–2024
Region / Location:
International
Subject:
Neurodegenerative Diseases / Protein Aggregation
Document Type:
Systematic Review
Institution / Organization:
Not specified
Authors:
Multiple peer-reviewed studies
Target Audience:
Researchers and clinicians in neurology and molecular biology
Date of Publication:
June 2024
Research Focus:
Effects of post-translational modifications on α-synuclein aggregation, structure, and toxicity
Methods:
Literature review of PubMed, Scopus, Web of Science using PRISMA framework
Key Findings:
Phosphorylation at Ser129 promotes aggregation; N-terminal acetylation and Ser87 phosphorylation reduce aggregation; C-terminal truncation and tyrosine nitration enhance neurotoxicity; PTM crosstalk affects aggregation and degradation pathways
Potential Applications:
PTM-specific α-synuclein species as biomarkers for diagnosis and disease staging
Document Type Classification:
Scientific review article
Year:
2026
Region / City:
Newcastle
Topic:
University Council Meeting
Document Type:
Meeting Agenda
Organization / Institution:
Newcastle University
Author:
Dr. C Campbell
Target Audience:
Council Members
Date of Approval:
12 January 2026
Date of Changes:
None
Year:
2025
Region / City:
Newcastle upon Tyne
Subject:
Tuition Fees Refund Process
Document Type:
Policy
Institution:
Newcastle University
Author:
Karen Carvell
Target Audience:
Students
Effective Date:
1 November 2025
Date of Update:
November 2025
Refund Conditions:
Available
Refund Process:
Described
Refund Method:
Bank Transfer, Credit/Debit Card, Third Party
Refund Limit:
£50
Refund Administration Fee:
£150
Year:
2025
Region / City:
Newcastle
Topic:
Social communication and interaction needs
Document Type:
Guidance
Organization:
Newcastle NHS Trust
Author:
Not specified
Target Audience:
Educational staff, families of children with social communication needs
Period of validity:
Ongoing
Date of approval:
June 2025
Date of amendments:
Not specified
Year:
2023
Region / city:
Diocese of Newcastle
Subject:
Child safety, Vulnerable people, Parish safety
Document type:
Self-assessment tool
Institution:
The Anglican Church of Australia
Author:
Not specified
Target audience:
Church staff, volunteers, parish members
Period covered:
Not specified
Date of approval:
Not specified
Date of amendments:
Not specified
Year:
2023
Region / City:
Newcastle
Theme:
Pet accommodation, hotel policies
Document Type:
Terms and Conditions
Organization:
Quest Newcastle
Author:
Quest Newcastle
Target Audience:
Pet owners, hotel guests
Validity Period:
Not specified
Approval Date:
Not specified
Amendment Date:
Not specified
Year:
2014
Region / city:
Newcastle
Topic:
Adult safeguarding
Document type:
Policy and procedure template
Organization / institution:
Newcastle Safeguarding Adults Board
Author:
Not specified
Target audience:
Managers, staff, volunteers, service users, and carers
Period of validity:
Ongoing
Approval date:
Not specified
Amendment date:
Not specified
Year:
2024
Region / City:
Newcastle
Theme:
SEND and Inclusion
Document Type:
Terms of Reference
Organization / Institution:
Newcastle City Council, NHS
Author:
Not specified
Target Audience:
Professionals in education, health, and social care
Period of Validity:
Not specified
Approval Date:
November 2024
Date of Changes:
November 2024
Year:
2022
Region / City:
Newcastle
Topic:
Cognition and Learning Needs
Document Type:
Guidance
Institution:
Sir Charles Parsons School
Author:
Unknown
Target Audience:
Educators, SENCOs, School Staff
Period of Effect:
From September 2022
Date of Approval:
September 2022
Date of Changes:
Not indicated
Year:
2022
Region / City:
Newcastle
Country:
United Kingdom
Subject Area:
Special Educational Needs and Disabilities
Focus:
Cognition and Learning Needs
Type of Document:
Guidance
Version:
1
Target Group:
Children and Young People
Educational Phase:
School Years
Related Framework:
SEND Code of Practice (January 2015)
Issuing Body:
Newcastle Local Authority
Assessment Framework:
Graduated Response (Assess, Plan, Do, Review)
Needs Levels Covered:
Range 1 to Range 6
Educational Settings:
Mainstream Schools
Source Type:
Local authority guidance document
Note:
Year
Topic:
Animal Health
Document Type:
Scientific Article
Organization / Institution:
World Organisation for Animal Health (OIE)
Target Audience:
Veterinary Professionals, Animal Health Authorities
Year:
2021
Region / City:
Newcastle
Topic:
Special Educational Needs (SEN)
Document Type:
Policy Guide
Organization:
Newcastle City Council
Author:
SENCO Team
Target Audience:
School Staff, SENCOs, Education Providers
Period of Validity:
Ongoing, Updated Annually
Approval Date:
September 2021
Date of Changes:
September 2021
Year:
2022
Region / City:
Newcastle
Topic:
Social, Emotional & Mental Health (SEMH)
Document Type:
Guidance
Institution:
Local Authority
Author:
Not specified
Target Audience:
School staff, mental health professionals, families
Period of Validity:
Ongoing
Approval Date:
September 2022
Date of Changes:
None specified
Context:
This document provides guidance for identifying and supporting children and young people with social, emotional, and mental health needs in educational settings.
Note:
Year
Region / city:
Newcastle upon Tyne
Subject:
Job application
Document type:
Application form
Organization / institution:
Royal Grammar School
Target audience:
Job applicants