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The document discusses the emergence and spread of Hendra and Nipah viruses in the 1990s, their impact on human and animal populations, and diagnostic procedures.
Year: 1990s
Region / City: Australia, Malaysia, Bangladesh, India, Philippines, Singapore
Topic: Zoonotic diseases, virus transmission, animal infections
Document type: Scientific Research
Author: Not specified
Target audience: Researchers, Public health professionals
Period of validity: Ongoing
Date of approval: Not specified
Date of changes: Not specified
Price: 8 / 10 USD
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Original Article: Critical Pathways of Osteoclast Development and Newcastle Disease Pathogenesis Study
Article Category: Original Article
Section Category: Microbiology
Title: Critical pathways of osteoclast development
Running title: Not specified
Authors: John Doe; Honglong Liu; Jeong-Hyun Kim
Affiliations: Department of Pathobiology, Auburn University Research Initiative in Cancer, College of Veterinary Medicine, Auburn University, Auburn, AL, USA; Safety Assessment Department, China Institute of Veterinary Drug Control, Beijing, China; Department of Veterinary Pharmacology and Research Center and Research Institute of Veterinary Science, College of Veterinary Medicine, Seoul National University, Seoul, Korea
Corresponding author: Jeong-Hyun Kim
Corresponding author email: [email protected]
ORCID: Provided for all authors
Equal contribution: John Doe and Honglong Liu
Conflict of Interest: The authors declare no conflicts of interest
Funding: Ministry of Education (2000R1A6A1A00000)
Data availability: Available from the corresponding author upon reasonable request
Ethics approval: Institutional Animal Care and Use Committee of OOOO (Approved number: 2023-0001)
Keywords: A; B; C; D; E
Study subjects: Wild Eurasian collared doves; experimental mice; pigs
Geographic reference: Konarak
Main topics: Newcastle Disease; osteoclast development; Brucella proteins; pathogen load analysis; differential gene expression
Methods: RT-PCR; absolute quantitative RT-PCR; RNA extraction; embryo candling; cDNA library sequencing; regression and subgroup analysis
Tables: Validation of selected DEGs by qRT-PCR; Demographic characteristics and clinical chemistry data
Figures: Histopathology of small intestine lesions; phylogenetic relationships of the HN gene
The roles of IL-17A and IL-17F in hidradenitis suppurativa pathogenesis: evidence from human in vitro preclinical experiments and clinical samples
Year: 2021
Region / City: Slough, UK
Topic: Immunology, Dermatology
Document Type: Research Article
Organization / Institution: UCB
Author: Joseph Rastrick, Hannah Edwards, Alex S. Ferecskó, Gaëlle Le Friec, Avneet Manghera, Matthew Page, Stevan Shaw
Target Audience: Researchers, Healthcare Professionals
Period of Validity: Not specified
Date of Approval: Not specified
Date of Changes: Not specified
Context: The document is a research article presenting findings on the roles of IL-17A and IL-17F in hidradenitis suppurativa (HS), based on human in vitro and clinical experiments.
Post-Translational Modifications of α-Synuclein: Drivers of Aggregation and Synucleinopathy Pathogenesis
Year: 2024
Region / city: N/A
Document type: Review article
Organization / institution: N/A
Author: N/A
Target audience: Researchers, scientists in neurobiology, biochemistry, and Parkinson’s disease studies
Period of action: N/A
Approval date: N/A
Modification date: N/A
An insight in the diagnosis and pathogenesis of hepatitis C virus infection
Journal: World Journal of Gastroenterology
Manuscript Number: 5269
Authors: Mohammad Irshad, Dhananjay Singh Mankotia, Khushboo Irshad
Affiliation: All India Institute of Medical Sciences, New Delhi, India
Received: August 26, 2013
Revised: September 11, 2013
Accepted: October 13, 2013
Published online: 2013
Keywords: Hepatitis C virus, Diagnosis, Pathogenesis, Immunity, Steatosis
Type of document: Review article
Focus: HCV infection diagnosis and pathogenesis
Target audience: Medical researchers, clinicians, and healthcare professionals
Herpes Viruses – Lecture 6: Classification, Morphology, Pathogenesis and Laboratory Diagnosis
Year: Not specified
Region / Country: Not specified
Academic Field: Virology
Topic: Human herpes viruses and associated diseases
Document Type: Lecture notes
Institution / Organization: Not specified
Author: Not specified
Target Audience: Medical or microbiology students
Viruses Discussed: Herpes simplex virus type 1 (HSV-1), Herpes simplex virus type 2 (HSV-2), Varicella-Zoster virus (VZV), Cytomegalovirus (CMV), Epstein-Barr virus (EBV), Human herpesvirus 6 (HHV-6), Human herpesvirus 7 (HHV-7), Human herpesvirus 8 (HHV-8)
Subfamilies: Alpha Herpesvirinae, Beta Herpesvirinae, Gamma Herpesvirinae
Genome Type: Double-stranded DNA (dsDNA)
Virion Structure: Core, Capsid, Tegument, Envelope
Transmission Routes: Direct contact, respiratory droplets, sexual transmission, perinatal transmission
Diseases Mentioned: Herpes simplex infection, Varicella (chickenpox), Herpes zoster (shingles)
Diagnostic Methods: Giemsa staining, electron microscopy, immunofluorescence, PCR, virus isolation, serology (ELISA, IF)
Key Biological Feature: Lifelong latency with periodic reactivation
Meningitis in Children: A Narrative Review of Epidemiology, Pathogenesis, Diagnosis and Management
Year: 2026
Journal: Journal of Medicine and Health Research
Manuscript Number: Ms_JOMAHR_14356
Type of Article: Review Article
Author: Not specified
Reviewer: Yerko Petar Ivanovic-Barbeito
Affiliation: Tallaght University Hospital, Ireland
Target Audience: Pediatricians, infectious disease physicians, neurologists, global health practitioners
Timeframe Covered: 2000–2025
Language: English
Ethical Considerations: No human subjects involved
Post-Translational Modifications of α-Synuclein and Their Role in Synucleinopathy Pathogenesis: Systematic Review 2010–2024
Year: 2010–2024
Region / Location: International
Subject: Neurodegenerative Diseases / Protein Aggregation
Document Type: Systematic Review
Institution / Organization: Not specified
Authors: Multiple peer-reviewed studies
Target Audience: Researchers and clinicians in neurology and molecular biology
Date of Publication: June 2024
Research Focus: Effects of post-translational modifications on α-synuclein aggregation, structure, and toxicity
Methods: Literature review of PubMed, Scopus, Web of Science using PRISMA framework
Key Findings: Phosphorylation at Ser129 promotes aggregation; N-terminal acetylation and Ser87 phosphorylation reduce aggregation; C-terminal truncation and tyrosine nitration enhance neurotoxicity; PTM crosstalk affects aggregation and degradation pathways
Potential Applications: PTM-specific α-synuclein species as biomarkers for diagnosis and disease staging
Document Type Classification: Scientific review article
Topics: Hendra Nipah Pathogenesis