№ files_lp_4_process_2_48946
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Study report on doxycycline residue levels in different bird species during treatment for Chlamydia psittaci, including field and controlled cases, highlighting species-specific excretion patterns and administration route effects.
Year:
2024
Institution:
Utrecht University; Wageningen University & Research
Type:
Master of Science research project
Supervisor:
Dr. Y.R.A. van Zeeland; Dr. R. Gehring; Dr. M. Heijne
Student:
T. Ploegers
Study period:
August 2019 – August 2020
Species studied:
Budgerigars and other avian species
Sample types:
Fecal and serum samples
Treatment methods:
Oral and intramuscular doxycycline
Objective:
Investigate residual excretion and pharmacokinetics of doxycycline
Ethical approval:
License AVD1080020184847 by CCD for university-collected samples
Source of field cases:
Dutch Food and Consumer Product Safety Authority (NVWA)
Version:
Final
Date:
August 4, 2024
Scope:
Zoonotic disease psittacosis, avian pharmacokinetics
Price: 8 / 10 USD
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Year:
2024
Region / City:
United Kingdom
Subject:
Doxycycline use during pregnancy
Document type:
Position statement
Organization / Institution:
BASHH (British Association for Sexual Health and HIV)
Author:
Ali Grant; on behalf of BASHH Clinical Effectiveness Group (CEG)
Target audience:
Healthcare professionals
Effective period:
Not specified
Approval date:
Not specified
Date of changes:
Not specified
Year:
2025
Region / City:
Massachusetts
Topic:
Lyme Disease, Postexposure Prophylaxis
Document Type:
Medical Guideline
Organization / Institution:
Massachusetts Department of Public Health
Author:
Massachusetts Department of Public Health
Target Audience:
Healthcare providers
Period of Effectiveness:
July 14, 2025
Approval Date:
July 14, 2025
Date of Changes:
N/A
Doxycycline 100mg Capsules Initial Supply for Tularemia Patient Group Direction (PGD), Version 6.00a
Publications reference number:
PRN01582
Reference:
Doxycycline 100mg capsules PGD initial supply tularemia
Version number:
6.00a
Valid from:
1 October 2024
Review date:
1 March 2027
Expiry date:
30 September 2027
Developed by:
UK Health Security Agency (UKHSA)
Legal framework:
Human Medicines Regulations 2012 (HMR2012), Schedule 16 Part 2
Type of document:
Patient Group Direction (PGD)
Medicinal product:
Doxycycline 100mg capsules
Indication:
Initial supply following known or suspected deliberate release of tularemia
Eligible population:
Adults and children aged 12 years and over not showing symptoms compatible with tularemia infection
Exclusion criteria:
Under 12 years, no valid consent, known severe hepatic impairment, taking enzyme inducing antiepileptics
Authorising organisations:
NHS organisations and commissioners in accordance with HMR2012
Record retention requirement:
25 years after PGD expiry
Change history latest update:
Correction of typo and mail hyperlink to [email protected]
Note:
on 4 November 2024
Developed by (named professional):
Kiran Attridge, Senior Medical Adviser
Year:
2024
Region / City:
UK
Topic:
Antimicrobial Prescribing, Antibiotics, Guidelines
Document Type:
Guidelines
Institution:
NICE (National Institute for Health and Care Excellence), UKHSA
Author:
National OptimiseRx Team
Target Audience:
Healthcare Professionals, Prescribers
Period of Validity:
November 2024
Approval Date:
November 2024
Date of Changes:
November 2024
Year:
Not specified
Region / City:
Not specified
Topic:
Osmoregulation, Excretion, Animal Physiology
Document Type:
Educational Text
Author:
Not specified
Target Audience:
Students, Biologists, Researchers
Effective Period:
Not specified
Approval Date:
Not specified
Revision Date:
Not specified
Year:
2023
Region / City:
Ohio, USA
Topic:
Nanotechnology, RNA Nanoparticles, Cancer Targeting
Document Type:
Research Article
Organization / Institution:
The Ohio State University, Wexner Medical Center
Author:
Hongzhi Wang, Chiran Ghimire, Hui Li, Mario Vieweger, Congcong Xu, Peixuan Guo
Target Audience:
Researchers, Scientists, Medical Professionals
Period of Validity:
N/A
Approval Date:
N/A
Date of Changes:
N/A
Note:
Context
Subject:
Biology
Topic:
Excretion
Level:
Secondary Education
Curriculum Code:
OB20–OB23
Document Type:
Educational Notes and Exam Preparation Material
Content Includes:
Syllabus, student notes, diagrams, exam questions, solutions
Key Concepts:
Urinary system, kidneys, waste removal, filtration, urine composition
Organs Covered:
Kidney, bladder, ureter, urethra, renal artery, renal vein, skin
Excretory Products:
Carbon dioxide, water, urea, salts
Assessment Material:
Past exam questions and solutions
Intended Audience:
Students preparing for biology examinations
Language:
English
Year:
2013
Exam:
WACE
Subject:
Biology
Topic:
Human Excretory System
Document type:
Examination Question Paper
Audience:
Students
Marks:
20 + 7 + 2 + 2 + 4 + 1
Key structures:
Glomerulus, Proximal convoluted tubule, Distal convoluted tubule, Collecting duct, Loop of Henle
Processes described:
Diffusion, Osmosis, Active transport
Functions:
Filtration, Reabsorption, Secretion, Urine concentration
Document type:
Supplemental research material
Scientific field:
Cardiology and renal physiology
Research topic:
Effects of glucocorticoids on renal sodium transport in heart failure
Authors:
Shuyu Li; Yaomeng Huang; Tongxin Li; Xiaoran Zhu; Weimin Li; Kunshen Liu; Chao Liu
Affiliated institutions:
North China University of Science and Technology Affiliated Hospital; The First Hospital of Hebei Medical University; Hebei General Hospital
Country of research:
China
Corresponding author:
Chao Liu
Experimental subjects:
Rat models of chronic heart failure
Methods:
Western blot analysis; immunohistochemistry; echocardiography; membrane protein extraction; sodium loading test
Key compounds studied:
Dexamethasone (DEX); RU486
Biological targets:
ENaC subunits; SGK1; NKCC2; Na⁺/K⁺-ATPase; SGLT1; SGLT2; NaPi-2a; NPRA; V2R; AQP2; AQP3; AQP4; NCC; NHE3
Measured parameters:
Fractional excretion of sodium (FeNa%); fractional excretion of potassium (FeK%); protein expression in renal cortex and medulla
Experimental groups:
Control rats; chronic heart failure rats; chronic heart failure rats treated with dexamethasone; intervention with RU486
Year:
2023
Institution:
Hokkaido University
Approval number:
17-0119
Animal model:
Male inbred WKAH/HkmSlc rats
Age of animals:
3 weeks
Sample size:
8 per group
Dietary intervention:
Control diet or 0.5 g CA/kg diet
Duration:
2 weeks
Housing conditions:
22 ± 2°C, 55 ± 5% humidity, 12 h light/dark cycle
Measurements:
Body weight, food intake, fecal lipid content
Analytical methods:
Cholesterol E-test, Triglyceride E-test, NEFA C-test
Reference diets:
AIN-93G-based control diet