№ lp_1_2_11359
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This document outlines a clinical trial for assessing the safety and feasibility of using tranexamic acid in patients with cerebral amyloid angiopathy to prevent brain bleeding, through a randomized controlled double-blind study.
Year:
2024
Region / city:
Australia
Topic:
Medical Research, Stroke, Cerebral Amyloid Angiopathy, Clinical Trial
Document Type:
Participant Information Sheet / Consent Form
Organization / institution:
Alfred Health
Author:
Dr. Oshi Swarup, Prof Geoffrey Cloud, Prof Nawaf Yassi
Target Audience:
Adults with Cerebral Amyloid Angiopathy
Period of Action:
26 weeks
Approval Date:
Not specified
Date of Changes:
Not specified
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The product description is provided for reference. Actual content and formatting may differ slightly.
Year:
2025
Region / City:
UK
Topic:
Healthcare, Medication Guidelines
Document Type:
Medical Protocol
Organisation:
National Ambulance Service Medical Directors (NASMeD)
Author:
Dr. Elizabeth Miller, Dr. Dave Macklin, Mr. Andy Curran, Rosie England, Cathryn James, Dan Haworth, Tracy Rogers, Jo Jenkins, Rosie Furner
Target Audience:
Registered healthcare professionals, Paramedics, Nurses, Midwives
Effective Date:
May 2023
Review Date:
October 2025
Expiry Date:
April 2026
Approval Date:
May 2025
Change History:
Includes updates to drug administration protocols and clinical guidelines
Year:
2016
Region / city:
Global
Topic:
Maternal health, Post-partum haemorrhage
Document type:
Research review
Organization / institution:
British Journal of Haematology, St Bartholomew’s Hospital, London School of Hygiene and Tropical Medicine
Author:
Stephen P Hibbs, Ian Roberts, Haleema Shakur-Still, Beverley J Hunt
Target audience:
Healthcare professionals, researchers, policymakers
Period of validity:
Ongoing
Approval date:
Not specified
Date of revisions:
Not specified
Year:
2024
Region / City:
Plymouth Meeting, Pa.
Topic:
Medication Safety
Document Type:
Press Release
Organization / Institution:
Institute for Safe Medication Practices (ISMP)
Author:
Renee Brehio
Target Audience:
Healthcare professionals, safety experts
Effective Period:
2024
Approval Date:
January 12, 2024
Date of Changes:
January 12, 2024
Year:
2007
Trial Registration:
EudraCT 2007-003666-17
Local R&I Number:
CS/2007/2608
Journal:
The New England Journal of Medicine
Publication Date:
Feb 25, 2016
Authors:
Paul S Myles, Julian A Smith, Andrew Forbes, Brendan Silbert, Mohandas Jayarajah, Thomas Painter, D James Cooper, Silvana Marasco, John McNeil, Jean S Bussieres, S Wallace
Research Network:
ANZCA Clinical Trials Network
Study Type:
Clinical trial
Medical Field:
Cardiac surgery / Pharmacology
Interventions:
Aspirin, Tranexamic Acid
Year:
2023
Region / city:
Global
Subject:
Bladder Cancer, Diagnostic Tests
Document Type:
Systematic Review and Meta-Analysis
Author:
Unspecified
Target Audience:
Researchers, Healthcare Professionals
Period of Validity:
2023
Date of Approval:
2023
Date of Changes:
Not specified
Supplementary Material:
Yes
Methodology:
PRISMA 2020 Checklist
Data Sources:
Databases, Registers, Websites, Organisations
Risk of Bias Assessment:
Included Studies
Statistical Methods:
Meta-Analysis, Heterogeneity Assessment
Results:
Statistical Synthesis, Sensitivity Analysis
Conflicts of Interest:
Unspecified
Funding:
Unspecified
Data Availability:
Publicly Available
Supplementary Figures:
Flow Charts
Year:
2023
Region / City:
California
Topic:
Paleoseismology, Earthquake Recurrence
Document Type:
Research Appendix
Institution:
University of Oregon, California Geological Survey, University of Nevada
Author:
Ray J. Weldon II, Timothy E. Dawson, Glenn Biasi, Christopher Madden, Ashley R. Streig
Target Audience:
Seismologists, Geologists, Researchers
Period of Validity:
2023 - Ongoing
Approval Date:
2023
Revision Date:
2023
Year:
2026
Study Type:
Clinical Data Analysis
Variables:
LAAV, LVEF, PWD
Outcome:
Atrial Fibrillation Recurrence
Statistical Method:
Net Reclassification Improvement (Continuous)
Population:
Patients at risk of AF recurrence
Data Presentation:
Reclassified events and non-events with logistic rates, expected numbers, and bootstrap confidence intervals
Source Type:
Supplementary Table
Year:
2026
Field:
Oncology, Genomics
Document type:
Research article supplementary material
Authors:
Yanding Zhao, Frederick S. Varn, Guoshuai Cai, Feifei Xiao, Christopher I. Amos, Chao Cheng
Institution:
Not specified
Target audience:
Medical researchers, oncologists, geneticists
Study population:
Patients with early stage lung adenocarcinoma
Data sources:
TCGA LUAD, TCGA LUSC, GSE3141, GSE42127, GSE68465, GSE13213, GSE4573, GSE8894, GSE14814
Methods:
PDS calculation, Mann-Whitney U test, Cox regression, log-rank tests
Variables analyzed:
P53 mutation type, smoking status, overall survival, recurrence risk
Supplementary content:
Figures S1–S5 with statistical analyses
Supplementary purpose:
Correlation of gene signature with recurrence and survival outcomes
Year:
2023
Region / City:
United Kingdom, Iceland, Portugal, Spain, The Netherlands, Italy, Sweden
Topic:
Renal Cell Carcinoma, Surgical Follow-Up
Document Type:
Research Study
Organization / Institution:
Royal Free London NHS Foundation Trust, University of Rennes, University College London, University of Bergen, University Medical Center Utrecht, University of Cambridge, Queen Mary University of London, Umeå University
Author:
Neves JB, Vanaclocha Saiz L, Abu-Ghanem Y, Marchetti M, Tran-Dang MA, El-Sheikh S, Barod R, Beisland C, Capitanio U, Cullen D, Klatte T, Ljungberg B, Mumtaz F, Patki P, Stewart GD, Dabestani S, Tran MGB, Bex A
Target Audience:
Medical professionals, Researchers in oncology, Urologists
Period of Action:
2015-2019
Approval Date:
2023
Modification Date:
N/A
Year:
2026
Region / City:
Not specified
Topic:
Breast cancer patient characteristics and outcomes
Document Type:
Supplementary data tables
Institution / Organization:
Not specified
Author:
Not specified
Study Population:
Patients with carcinoma in situ and invasive carcinoma
Sample Size:
491
Clinical Parameters:
Age, tumor size, molecular typing, type of surgery, lymph node status
Imaging Parameters:
Ultrasonography (US), Mammography, BI-RADS categories, calcification
Follow-up Period:
Not specified
Recurrence and Metastasis Analysis:
Univariate proportional hazard analysis
Data Collection Methods:
Clinical examination, pathologic evaluation, imaging studies
Year:
2026
Topic:
Combinatorics, Recurrence Relations, Counting Problems
Document Type:
Worksheet with Solutions
Audience:
Students preparing for mathematical competitions
Problems Included:
Grid paths, Frog jumps, Tiling, Circular handshakes, Wicked sets
Difficulty Level:
Advanced
Mathematical Concepts:
Recurrence relations, Combinatorial formulas, Fibonacci sequence, Geometric series
Source:
BMO Round 1 examples referenced
Context:
A set of combinatorial exercises with step-by-step solutions illustrating recurrence relations and counting techniques across various discrete mathematics problems.
Regulatory framework:
BCAR Section A3-7
Jurisdiction:
United Kingdom
Aviation authority:
UK Civil Aviation Authority
Document type:
Aircraft maintenance programme
Aircraft category:
Aeroplanes and helicopters
Operational basis:
UK National Permit to Fly
Approval status:
CAA approval required
Applicable regulation:
BCAR A3-7
Associated organisations:
Type Certificate Holder; Organisation Responsible for Type Design; Original Equipment Manufacturers
Review interval:
Not exceeding 12 months
Intended operator role:
Owner / CAMO
Content scope:
Scheduled maintenance; continued airworthiness; modifications and repairs; mandatory requirements; parking and storage; life-limited parts; fatigue monitoring
Year:
2020
Region / City:
United Kingdom
Subject:
Aircraft maintenance
Document Type:
Aircraft Maintenance Programme (AMP)
Organization:
Royal Air Force Gliding & Soaring Association
Author:
M Dearden
Target Audience:
Aircraft maintenance personnel, gliding associations, and aviation operators
Approval Date:
13th March 2020
Modification Date:
15th November 2023
Aircraft Registration:
G-CHEE
Aircraft Type:
Discus B
Serial Number:
292
Design Approval Holder:
Schempp-Hirth Flugzeugbau GmbH
Maintenance Instructions:
Yes
Maintenance Tasks:
Yes
ICA Reference:
EASA.A.049
Appendix A:
Yes
Appendix B:
Yes
Appendix C:
Yes
Appendix D:
Yes
Note:
Year
Contextual description:
Document outlines the knowledge and skills necessary for speech-language pathology students, detailing academic courses, practicum experiences, and competencies across multiple areas of the discipline, including evaluation, intervention, and professional practice.
Year:
2023
Region / City:
New Zealand
Topic:
Flight test application
Document Type:
Application form
Organization / Institution:
Civil Aviation Authority (CAA)
Author:
Civil Aviation Authority (CAA)
Target Audience:
Individuals applying for flight tests
Period of Validity:
N/A
Approval Date:
N/A
Date of Changes:
N/A
Note:
Year
Topic:
Aircraft Radio Station Equipment Approval
Document Type:
Form
Organization:
Civil Aviation Authority
Target Audience:
Aircraft Operators, Certification Authorities
Year:
2020
Region / City:
East Anglia
Theme:
Cadet Force Administration
Document Type:
Job Description
Organization:
Reserve Forces and Cadets Association for East Anglia (RFCA East Anglia)
Author:
RFCA East Anglia
Target Audience:
Cadet Force Adult Volunteers (CFAV), Cadet Executive Officers (CEO), Area HQ staff
Period of Validity:
Ongoing
Approval Date:
February 20, 2020
Date of Last Revision:
Not specified
Year:
2018
Region / City:
Norfolk, UK
Subject:
Cadet Force Administration
Document Type:
Job Description
Organization:
Reserve Forces and Cadets Association (RFCA)
Author:
Not specified
Target Audience:
Cadet Force Adult Volunteers, Administrative Staff
Period of Activity:
Not specified
Approval Date:
Not specified
Date of Changes:
Not specified
Year:
2017
Region:
United Kingdom
Subject:
Aviation, Pilot Training
Document Type:
Annex / Equipment List
Organization:
Civil Aviation Authority (CAA)
Target Audience:
ATPL students
Required Equipment:
Clear plastic ruler, approved calculator, approved flight computers, Jeppesen GSPRM, protractor, compass and dividers, fine tip marker, A4 hard paper copies of CAP 696, CAP 697, CAP 698
Source:
CAA website and Pathway publications
Exam Requirements:
Items must be pre-purchased and available for use in exams