№ files_lp_4_process_2_48417
Gene expression study data with supplementary figures showing correlations between P53-deficiency signature, mutation type, smoking status, and survival outcomes in early stage lung adenocarcinoma and squamous cell carcinoma datasets.
Year: 2026
Field: Oncology, Genomics
Document type: Research article supplementary material
Authors: Yanding Zhao, Frederick S. Varn, Guoshuai Cai, Feifei Xiao, Christopher I. Amos, Chao Cheng
Institution: Not specified
Target audience: Medical researchers, oncologists, geneticists
Study population: Patients with early stage lung adenocarcinoma
Data sources: TCGA LUAD, TCGA LUSC, GSE3141, GSE42127, GSE68465, GSE13213, GSE4573, GSE8894, GSE14814
Methods: PDS calculation, Mann-Whitney U test, Cox regression, log-rank tests
Variables analyzed: P53 mutation type, smoking status, overall survival, recurrence risk
Supplementary content: Figures S1–S5 with statistical analyses
Supplementary purpose: Correlation of gene signature with recurrence and survival outcomes
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