№ files_lp_3_process_9_38062
File format: docx
Character count: 182139
File size: 243 KB
Supplementary scientific material presenting figures and enrichment tables that characterize genomic distribution, differential methylation patterns, and functional pathway associations of methylated sites in polyp and control tissue samples.
Document type:
Supplementary material
Subject:
Differential DNA methylation analysis
Keywords:
DNA methylation, DMPs, DMRs, CpG island, GO enrichment, KEGG pathway, polyps, normal tissue
Biological context:
Comparison between polyp and control tissue samples
Analytical methods:
Correlation heatmap, box plot normalization, differential methylation analysis, GO and KEGG enrichment analysis
Genes mentioned:
LPA, SVIL, KRT18, MYH13 and others listed in enrichment tables
Statistical measures:
Pearson’s correlation coefficient, T value, pvalue, adjusted pvalue, qvalue
Biological processes highlighted:
Regulation of membrane potential, axon guidance, extracellular matrix organization, ion transmembrane transport
Abbreviations:
TSS (transcription start site), P (polyp), C (control), FEM (Functional epigenetic modules), DMP (differentially methylated position), DMR (differentially methylated region)
Price: 8 / 10 USD
The file will be delivered to the email address provided at checkout within 12 hours.
The file will be delivered to the email address provided at checkout within 12 hours.
Don’t have cryptocurrency yet?
You can still complete your purchase in a few minutes:- Buy Crypto in a trusted app (Coinbase, Kraken, Cash App or any similar service).
- In the app, tap Send.
- Select network, paste our wallet address.
- Send the exact amount shown above.
The final amount may vary slightly depending on the payment method.
The file will be sent to the email address provided at checkout within 24 hours.
The product description is provided for reference. Actual content and formatting may differ slightly.
Year:
2024
Region / City:
United States
Topic:
Medical Appeal Letter
Document Type:
Template
Organization / Institution:
OptiNose, Inc.
Author:
OptiNose, Inc.
Target Audience:
Healthcare providers, medical professionals
Period of Validity:
Indefinite
Approval Date:
05/2024
Date of Changes:
None
Year:
2017-2018
Region / City:
Doncaster
Subject:
Healthcare, Gynaecology
Document Type:
Service Specification
Organisation:
CCG
Author:
Not specified
Target Audience:
Healthcare Providers, GPs
Period of Validity:
1st April 2017 to 31st March 2018
Approval Date:
Not specified
Date of Review:
Annual
Date of Changes:
Not specified
Year:
2025
Note:
Region / city
Topic:
Central nervous system tumor diagnostics
Document type:
Scientific article
Author:
Aldape K, Capper D, von Deimling A, Giannini C, Gilbert MR, Hawkins C, Hench J, Jacques TS, Jones D, Louis DN, Mueller S, Orr BA, Nasrallah M, Pfister SM, Sahm F, Snuderl M, Solomon D, Varlet P, Wesseling P
DOI:
10.1093/noajnl/vdae228
PMID:
39902391
PMCID:
PMC11788596
Context:
A scientific article offering guidelines on the use of DNA methylation profiling for diagnosing tumors in the central nervous system.
Year:
2017
Region / City:
Netherlands, Canada
Topic:
DNA Methylation Analysis
Document Type:
Research Supplementary Materials
Institution:
Not specified
Author:
Forest et al.
Target Audience:
Researchers in genomics and molecular biology
Period of validity:
Not specified
Date of approval:
Not specified
Date of changes:
Not specified
Year:
2022
Region / city:
Global
Theme:
DNA methylation analysis
Document type:
Product datasheet
Organization / institution:
Abcam
Author:
Abcam
Target audience:
Researchers in molecular biology, genetics, and biochemistry
Validity period:
Not specified
Approval date:
21 June 2022
Modification date:
Not specified
Year:
2026
Institution:
Johns Hopkins Hospital, Asan Medical Center
Study Type:
Molecular biology study
Methods:
Droplet digital PCR, MSP, bisulfite sequencing, ddQMSP, mRNA expression analysis
Biomarkers:
SOX17, ACTB, KRAS, GNAS, seven marker genes
Sample Type:
Surgically aspirated pancreatic cyst fluid, pancreatic cell lines, normal pancreatic tissue
Sample Size:
183 patients (discovery and validation sets)
Pathology:
IPMN, MCN, SCN, HGD, INV, IGD, LGD
Data Presentation:
1-D ddPCR plots, heat maps, AUC values, box plots, correlation plots
Statistical Measures:
Mean ± standard deviation, coefficient of determination (R²), coefficient of variation (% CV), 95% confidence interval
Experimental Conditions:
5-Aza-2′-deoxycytidine, trichostatin A treatment
Comparisons:
Between hospitals (JHH vs AMC), among cyst types, stratified by mutation status and histologic grade
Year:
2025
Region / city:
China
Subject:
Nasopharyngeal carcinoma, RNA modification
Document type:
Original research article
Institution:
University hospital, Otolaryngology department
Author:
Not specified
Target audience:
Researchers, clinicians
Period of validity:
Not specified
Approval date:
Not specified
Date of revisions:
Not specified
Year:
2026
Region / City:
Not specified
Subject:
TP53 mutations, DNA methylation, GC patients
Document Type:
Supplementary material
Institution:
Not specified
Author:
Not specified
Target Audience:
Researchers and clinicians in molecular genetics and oncology
Methods:
Sanger sequencing, pyrosequencing, primer design
Data Source:
Patient tumor samples
Genomic Reference:
GRCh37: Genome Reference Consortium human build 37
Figures Included:
Methylation distribution and survival analysis
Tables Included:
Primer sequences, TP53 mutations
Clinical Context:
Neoadjuvant and adjuvant chemotherapy subgroups
Year:
Not specified
Region / City:
Not specified
Subject:
DNA methylation, LRP11, HCC
Document Type:
Supplementary figure
Organization / Institution:
SMART database
Author:
Not specified
Target Audience:
Researchers in genomics
Effective Period:
Not specified
Approval Date:
Not specified
Date of Changes:
Not specified
Year:
2026
Study Population:
Whites
Sample Type:
Plasma, Urine
Disease Focus:
Cancer
Number of Cancer Cases:
41
Number of Control Cases:
11
Genes Analyzed:
CDO1, TAC1, HOXA7, HOXA9, SOX17, ZFP42
Parameters Measured:
Sensitivity, Specificity, Positive Predictive Value (PPV), Negative Predictive Value (NPV), Area Under the Curve (AUC), 95% Confidence Interval
Data Presentation:
Tabular
Cutoff Criteria:
Detectable vs. Non-detectable
Combined Analysis:
At least 3 positive genes
Year:
2023
Region / City:
Denmark
Theme:
Cervical Cancer Screening, HPV Testing, DNA Methylation
Document Type:
Research Article
Organization / Institution:
University Research Clinic for Cancer Screening, Aarhus University
Authors:
Mette Tranberg, Severien Van Keer, Albertus T Hesselink, Pia Nørgaard, Rikke Brøndum, Chunsen WU, Line Winther Gustafson, Anne Hammer, Pinar Bor, Karen Omann Binderup, Christina Blach, Alex Vorsters, Renske Steenbergen
Target Audience:
Researchers, Healthcare Professionals, Medical Community
Period of Application:
Not specified
Approval Date:
Not specified
Date of Changes:
Not specified
Study Registration:
Clinicaltrials.gov: NCT05065853
Keywords:
DNA methylation, cervical cancer screening, HPV DNA testing, urinary HPV testing, early detection of cancer/methods
Abstract:
The study evaluates the performance of ASCL1/LHX8 DNA methylation markers and HPV genotyping in first-void urine samples for detecting high-grade cervical intraepithelial neoplasia (CIN2+) and cervical cancer in HPV-positive women, comparing it with clinician-collected cervical samples.
Document Type:
Supplementary data description
Content Type:
Data file index and variable definitions
Research Field:
Epigenetics; Neurodegenerative disease research
Disease Focus:
Parkinson’s disease
Biological Material:
Human prefrontal cortex nuclei samples
Cell Types:
NeuN+ neuronal nuclei; SOX10+ oligodendrocyte nuclei; double negative glial nuclei
Genetic Factor:
GBA1 variant status
Data Types:
Sample metadata; quality control metrics; cell composition estimates; differential DNA methylation results; gene ontology analysis
Analytical Methods:
EWAS (epigenome-wide association study); linear regression analysis; interaction models; Tukey HSD test; ANOVA; χ² test
Laboratory Methods:
EPIC DNA methylation array; bisulfite conversion; fluorescence-activated nuclei sorting (FANS)
Variables Included:
PD status; GBA1 status; sex; dementia status; Braak Lewy body stage; Braak neurofibrillary tangle stage; methylation signal intensity; principal components; genomic site coordinates
Sample Groups:
PD-GBA1; PD-non-GBA1; Control-GBA1; Control-non-GBA1
Brain Region:
Prefrontal cortex
Number of Supplementary Files:
14
File Formats:
XLS spreadsheets
Key Measurements:
DNA methylation beta values; cell composition fractions; quality control metrics; differential methylation statistics
Year:
2017
Region / City:
Miami, FL
Topic:
Maintenance and Calibration Services
Document Type:
Solicitation Notice
Organization / Institution:
Department of Veterans Affairs
Author:
Paul Jarrett, Contracting Officer
Target Audience:
Small Business Offerors
Performance Period:
June 1, 2017 to May 31, 2022
Approval Date:
May 23, 2017
Amendments Date:
N/A
Note:
Year
Document Type:
Employment Equity Report
Organ / Institution:
Department of Employment and Labour
Author:
N/A
Target Audience:
Employers in South Africa
Effective Period:
For reporting year
Approval Date:
N/A
Amendment Date:
N/A
Year:
2023
Region / City:
Ireland
Subject:
Applied Mathematics
Document Type:
Educational Booklet
Institution:
thephysicsteacher.ie
Author:
Noel Cunningham
Target Audience:
Students preparing for higher level and ordinary level applied mathematics exams
Period of Effect:
1971–2023
Approval Date:
04/11/2023
Date of Last Update:
04/11/2023
Note:
Course Eligibility
Year:
Fall 2025
Region / City:
LSU
Subject:
Differential Calculus
Document Type:
Syllabus
Institution:
Louisiana State University
Author:
Instructor of Record
Target Audience:
High school students enrolled in Dual Enrollment program
Action Period:
Fall 2025
Approval Date:
[not provided]
Modification Date:
[not provided]
Contextual Description:
A syllabus for a dual enrollment math course on differential calculus, outlining eligibility requirements, course materials, structure, homework guidelines, quizzes, and the LSU code of conduct.
Course Code:
MATH 120
Course Title:
Linear Algebra with Differential Equations
Academic Term:
Spring 2014–2015
Credit Hours:
3
Lecture Duration:
2 lectures per week, 75 minutes each
Instructor:
Adnan Khan; Sultan Sial
Room Number:
249 SSE
Email:
[email protected]
Telephone:
8015
Secretary/TA:
Shazia Tabassum
Course URL:
http://suraj.lums.edu.pk/~adnan.khan/classes/classes/LinearAlgebra/
Prerequisites:
Math in A Levels, FSc or Equivalent
Assessment Breakdown:
Assignments 9%; Homework 16%; Midterm Examination 35%; Final Examination 40%
Textbooks:
Elementary Linear Algebra (Howard Anton, 9th edition, 2005); Differential Equations with Boundary Value Problems (Dennis Zill and Michael Cullin, 5th edition); A First Course in Linear Algebra (R.A. Beezer, 2010); Linear Algebra and Its Applications (Gilbert Strang, 4th edition)
Software:
MATLAB; WolframAlpha
Topics Covered:
Systems of Linear Equations; Matrices; Determinants; Vector Spaces; Linear Transformations; Inner Products; Eigenvalues and Eigenvectors; Differential Equations
Note:
Year
Topic:
Differential Equations, Linear Algebra, Partial Differential Equations
Document Type:
Syllabus
Institution:
Florida Atlantic University
Author:
Dr. Terje Hoim
Target Audience:
Students enrolled in the course
Period of Effect:
Fall 2023
Prerequisite:
MAP 2302
Tests (60%):
4 in-class exams, each covering a chapter
Quizzes (10%):
Regular in-class quizzes
Homework (5%):
Assigned homework problems
Final Exam (25%):
Comprehensive
Grading Scale:
A (93.5-100), A- (89.5-93.49), B+ (86.5-89.49), etc.
Make-Up Policy:
One day per missed class to make up work
Workload:
6-9 hours per week outside of class
Classroom Etiquette:
No personal communication devices allowed
Accommodations:
Register with Office for Students with Disabilities for accommodations
Academic Integrity:
Strict adherence to ethical standards required
Note of Honors Distinction:
Enhanced writing component, exposure to theoretical vocabulary, interdisciplinary learning
Year:
2025/26
Region / City:
Karratha
Theme:
Local Government, Property Taxation, Municipal Budget
Document Type:
Policy Document
Agency / Institution:
City of Karratha
Author:
City of Karratha Council
Target Audience:
Property owners, business owners, and residents within the City of Karratha
Period of Action:
2025/26 Financial Year
Approval Date:
Not specified
Date of Changes:
Not specified
Year:
2021
Region / city:
Queensland, Australia
Topic:
miRNA expression analysis, pleural effusions, extracellular vesicles
Document type:
Research article
Institution:
The University of Queensland Thoracic Research Centre, The Prince Charles Hospital
Authors:
Tian Mun Chee, Caeli J. Zahra, Kwun M. Fong, Ian A. Yang, Rayleen V. Bowman
Target audience:
Researchers in molecular biology, oncology
Period of validity:
N/A
Approval date:
N/A
Date of changes:
N/A