№ files_lp_4_process_3_111239
Year: 2023
Region / City: Denmark
Theme: Cervical Cancer Screening, HPV Testing, DNA Methylation
Document Type: Research Article
Organization / Institution: University Research Clinic for Cancer Screening, Aarhus University
Authors: Mette Tranberg, Severien Van Keer, Albertus T Hesselink, Pia Nørgaard, Rikke Brøndum, Chunsen WU, Line Winther Gustafson, Anne Hammer, Pinar Bor, Karen Omann Binderup, Christina Blach, Alex Vorsters, Renske Steenbergen
Target Audience: Researchers, Healthcare Professionals, Medical Community
Period of Application: Not specified
Approval Date: Not specified
Date of Changes: Not specified
Study Registration: Clinicaltrials.gov: NCT05065853
Keywords: DNA methylation, cervical cancer screening, HPV DNA testing, urinary HPV testing, early detection of cancer/methods
Abstract: The study evaluates the performance of ASCL1/LHX8 DNA methylation markers and HPV genotyping in first-void urine samples for detecting high-grade cervical intraepithelial neoplasia (CIN2+) and cervical cancer in HPV-positive women, comparing it with clinician-collected cervical samples.
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