№ lp_1_2_06586
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Character count: 11632
File size: 556 KB
This guideline provides recommendations for the use of low-dose aspirin as a preventive measure for preterm preeclampsia in pregnant women at high risk.
Year:
2023
Region / city:
Canberra, Australia
Topic:
Obstetrics, Pre-eclampsia, Pregnancy Care
Document type:
Guideline
Organization / institution:
Canberra Health Services
Author:
Society of Obstetric Medicine Australia and New Zealand (SOMANZ)
Target audience:
Medical Officers, Registered Nurses, Registered Midwives, Students, Pharmacists
Period of validity:
Not specified
Approval date:
2023
Date of amendments:
Not specified
Price: 8 / 10 USD
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The product description is provided for reference. Actual content and formatting may differ slightly.
Title:
Preparation of Aspirin
Document Type:
Laboratory Guide
Subject:
Chemistry
Topic:
Synthesis of Aspirin
Chemical Reaction:
Condensation of 2-hydroxybenzoic acid with ethanoic anhydride
Product:
Aspirin (acetylsalicylic acid)
Educational Level:
Pupil
Required Chemicals:
2-hydroxybenzoic acid; ethanoic anhydride; 85% phosphoric acid; ethanol; deionised water
Required Equipment:
Conical flasks; measuring cylinders; beakers; thermometers; balance; hot plate; Buchner funnel and flask; water pump; oven; melting point apparatus
Safety Requirements:
Use of eye protection (BS EN166 3); gloves; fume cupboard handling
Procedure Includes:
Heating to 85°C; recrystallisation; filtration; drying; melting point determination
Analytical Methods:
Determination of melting point; calculation of percentage yield
Year:
2026
Region / City:
Liverpool, UK
Topic:
Antiplatelet therapy, Staphylococcal infections, ACS
Document Type:
Research Study
Organization / Institution:
University of Liverpool, Liverpool University Hospital NHS Foundation Trust
Author:
Hani Essa, Wern Yew Ding, Faraz Rana, Sizheng Steven Zhao, Matthew Anson, Philip Austin, Gema Hernández, Pankaj Lal, Gregory Y. H. Lip, Uazman Alam
Target Audience:
Healthcare professionals, researchers in cardiovascular medicine, infectious disease specialists
Study Period:
5 years
Date Approved:
2026-03-06
Date Modified:
2026-03-06
Year:
1897
Region / city:
Not specified
Topic:
Chemistry, Esterification, Synthesis of Aspirin
Document type:
Laboratory Experiment Procedure
Organization / Institution:
Bayer (mentioned in context)
Author:
Not specified
Target audience:
Chemistry students, laboratory professionals
Period of validity:
Not specified
Date of approval:
Not specified
Date of changes:
Not specified
Year:
2007
Trial Registration:
EudraCT 2007-003666-17
Local R&I Number:
CS/2007/2608
Journal:
The New England Journal of Medicine
Publication Date:
Feb 25, 2016
Authors:
Paul S Myles, Julian A Smith, Andrew Forbes, Brendan Silbert, Mohandas Jayarajah, Thomas Painter, D James Cooper, Silvana Marasco, John McNeil, Jean S Bussieres, S Wallace
Research Network:
ANZCA Clinical Trials Network
Study Type:
Clinical trial
Medical Field:
Cardiac surgery / Pharmacology
Interventions:
Aspirin, Tranexamic Acid
Year:
2006
Region / City:
Australia
Topic:
Medication management, disability services
Document Type:
Legal / Regulatory
Organization:
Disability Services
Author:
Not specified
Target Audience:
Healthcare providers, professionals in disability services
Effective Period:
Ongoing
Approval Date:
Not specified
Amendment Date:
Not specified
Year:
2023
Region / City:
Australia
Subject:
Chronic migraine, medicinal product submission
Document type:
Submission for PBS listing
Organization:
Novartis Pharmaceuticals Australia Pty. Limited
Author:
Not specified
Target audience:
Health professionals, pharmaceutical regulatory bodies
Period of validity:
Not specified
Date of approval:
2 July 2018
Date of amendments:
November 2023
Year:
2024
Regulatory authority:
Therapeutic Goods Administration (TGA)
Medicine:
MACITENTAN 10 mg with TADALAFIL 40 mg (Opsynvi®)
Indication:
Pulmonary arterial hypertension (PAH), WHO Group 1, functional class II and III
Therapy type:
Dual or triple combination therapy
Dosage form:
Tablet, fixed dose combination (FDC)
Prescriber type:
Medical practitioners
Restriction type:
Authority Required (Written, Complex Authority Required)
Clinical criteria:
Treatment as dual therapy (MAC+TAD) or triple therapy with prostanoid
Population:
Adult patients with stable PAH on separate doses of macitentan and tadalafil
Previous considerations:
PBAC recommendations for macitentan and tadalafil since 2011–2014
Approval date:
16 September 2024
Source documents:
TGA registration, PBAC meeting minutes, ACM minutes August 2024, FDA, EMA, CDA references
Note:
Year
Subject:
High Dose Antipsychotic Monitoring
Document Type:
Medical Form
Institution:
Oxford Health
Target Audience:
Healthcare professionals
Year:
2024
Region / city:
United Kingdom
Subject:
Radiological Protection, Transport of Radioactive Materials
Document Type:
Technical Assessment Guide
Organization:
Office for Nuclear Regulation (ONR)
Author:
Inspector - Nuclear Safety
Target Audience:
ONR safety inspectors
Validity Period:
October 2024 - October 2029
Approval Date:
October 2024
Revision Date:
Not applicable
Document Reference:
NS-TAST-GD-100
Record Reference:
2020/281169
Issue:
2.1
Purpose:
Guidance for assessing shielding designs and dose rates of transport packages for radioactive materials.
Scope:
Focuses on shielding and dose rate assessments in accordance with IAEA regulations for transport safety.
Related Legislation:
IAEA SSR-6 (2018), UK regulations for radioactive materials transport
Note:
Contextual Description
Year:
Not specified
Region / City:
Not specified
Topic:
Infliximab dose escalation in Crohn’s disease treatment
Document type:
Medical request letter
Institution / Organization:
Not specified
Author:
Not specified
Target audience:
Insurance company
Period of validity:
Not specified
Approval date:
Not specified
Date of modifications:
Not specified
Note:
Year
Topic:
Lung disease, steroid treatment
Document type:
Information sheet
Organization / institution:
Sheffield Teaching Hospitals NHS Foundation Trust
Author:
Respiratory and endocrinology teams
Target audience:
People with lung disease on high dose inhaled steroids
Year:
2022
Region / City:
Australia
Subject:
Pharmacology, Pharmaceutical Benefits Scheme (PBS)
Document Type:
Submission
Organization / Institution:
Sanofi-Aventis Australia Pty Ltd
Author:
Not specified
Target Audience:
Medical practitioners, healthcare professionals
Period of validity:
Not specified
Approval Date:
3 June 2022
Date of Changes:
Not specified
Contextual Description:
A regulatory submission detailing the request for listing of dupilumab in new forms for treating severe atopic dermatitis and uncontrolled severe asthma in pediatric patients under the PBS.
Note:
Year
Background:
The submission requested a General Schedule Authority Required (Telephone/Online) listing of a new form of adrenaline (epinephrine) acid tartrate 150 micrograms/0.15 mL autoinjector (AI) (Jext® Junior (Jr)) and 300 micrograms/0.3 mL AI (Jext®) under the same circumstances as the currently listed adrenaline (epinephrine) 150 microgram/0.3 mL AI (EpiPen® Jr and Anapen® Jr 150) and 300 microgram/0.3 mL AI (EpiPen® and Anapen® 300).
Year:
Not specified
Region / city:
Not specified
Theme:
Clinical Trials, Dose Escalation
Document type:
Protocol
Organization / institution:
Not specified
Author:
Not specified
Target audience:
Clinical researchers, Principal Investigators
Period of validity:
Not specified
Approval date:
Not specified
Date of amendments:
Not specified
Year:
2022
Region / City:
Australia
Topic:
Medicinal Product Submission
Document Type:
Submission for Pharmaceutical Listing
Organization / Institution:
Pharmaceutical Benefits Advisory Committee (PBAC)
Author:
Not specified
Target Audience:
Healthcare professionals, policy makers
Period of Validity:
Not specified
Approval Date:
10 August 2022
Date of Changes:
Not specified
Year:
2021
Region / City:
Australia
Topic:
Atopic dermatitis treatment, medication submission
Document Type:
Submission report
Organization / Institution:
Sanofi-Aventis Australia Pty Ltd
Author:
Sanofi-Aventis
Target Audience:
Medical professionals, regulatory authorities
Action Period:
Ongoing treatment evaluation
Approval Date:
17 August 2021
Modification Date:
Not specified
Background:
Dupilumab registration history
Clinical Claim:
Dupilumab has superior efficacy compared to standard care for children with severe atopic dermatitis
Episodicity:
Chronic
Severity:
Severe
Condition:
Atopic dermatitis
PBS Indication:
Chronic severe atopic dermatitis
Prescriber Type:
Medical practitioners, dermatologists, clinical immunologists
Treatment Phase:
Initial, continuing
Population Criteria:
Children aged 6 to 11 years, specific weight ranges
Comparator:
Placebo
Outcomes:
EASI-75, IGA 0 or 1 at Week 16, improvement in itch score
Dosing:
Tiered by body weight
Cost:
$1,754.28–$3,380.91
Price:
Published price for maximum quantity
Form:
Pre-filled syringe
Medical Information:
Dupilumab 300 mg/2 mL, 200 mg/1.14 mL
Note:
Comparator
Standard of care (Placebo)
Source:
PBAC submission
Year:
2016
Region / city:
United Kingdom
Topic:
Medical imaging, Radiation dose reduction
Document Type:
Guidelines
Organization / institution:
Royal College of Radiologists, British Association of Urological Surgeons
Author:
Dr. John Maguire, Nicola Spence, Dr. Karen Gray
Target Audience:
Radiologists, CT radiographers
Effective Period:
Ongoing
Approval Date:
28 January 2016
Last Reviewed:
8 April 2018
Year:
not specified
Country:
United Kingdom
Medication:
Zopiclone
Therapeutic class:
Hypnotic
Indication:
Insomnia
Licensed use duration:
Up to 4 weeks
Adult licensed dose:
7.5 mg at bedtime
Elderly licensed dose:
3.75–7.5 mg at bedtime
Off-licence use:
Yes
Primary topic:
Dose reduction and withdrawal
Withdrawal risks:
Physical and psychological withdrawal symptoms
Target population:
Adult patients using zopiclone long term
Recommended tapering pace:
No faster than one change per week
Dose forms:
3.75 mg tablets, 7.5 mg tablets
Reference bodies:
All Wales Medicines Strategy Group; NICE
Document components:
Clinical guidance; tapering schedule; patient reduction record
Note:
Year
Topic:
Medication Administration
Document Type:
Guidelines
Target Audience:
Staff in care homes
Year:
2021
Country:
Global
Topic:
COVID-19 vaccination during pregnancy
Document Type:
Supplementary material
Study Type:
Systematic review
Authors:
Not specified
Target Audience:
Researchers, healthcare professionals, policy makers
Period of validity:
Not specified
Approval Date:
Not specified
Date of Changes:
Not specified