№ lp_1_2_45810
File format: docx
Character count: 4353
File size: 64 KB
Clinical guidance text outlining pharmacology, licensing limits, withdrawal risks, and a staged dose reduction schedule for discontinuing long-term zopiclone use, including a patient-held tapering record.
Year:
not specified
Country:
United Kingdom
Medication:
Zopiclone
Therapeutic class:
Hypnotic
Indication:
Insomnia
Licensed use duration:
Up to 4 weeks
Adult licensed dose:
7.5 mg at bedtime
Elderly licensed dose:
3.75–7.5 mg at bedtime
Off-licence use:
Yes
Primary topic:
Dose reduction and withdrawal
Withdrawal risks:
Physical and psychological withdrawal symptoms
Target population:
Adult patients using zopiclone long term
Recommended tapering pace:
No faster than one change per week
Dose forms:
3.75 mg tablets, 7.5 mg tablets
Reference bodies:
All Wales Medicines Strategy Group; NICE
Document components:
Clinical guidance; tapering schedule; patient reduction record
Price: 8 / 10 USD
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The product description is provided for reference. Actual content and formatting may differ slightly.
Year:
2023
Region / city:
UK
Topic:
Tapering regimen for benzodiazepine withdrawal
Document type:
Medical guideline
Organization / institution:
NHS Wales
Author:
Not specified
Target audience:
Healthcare professionals
Period of validity:
Not specified
Approval date:
Not specified
Date of amendments:
Not specified
Note:
Year
Year:
2021
Language:
English
Medical field:
Pain management
Therapeutic class:
Gabapentinoids
Medications covered:
Gabapentin; Pregabalin
Indications discussed:
Neuropathic pain
Patient population:
Adults with persistent pain
Document type:
Clinical guidance
Related guidance:
Analgesic Tapering Guidelines for adult patients with persistent pain taking strong opioids and/or gabapentinoids
Regulatory references:
NICE; MHRA
Dosage information:
Included
Tapering schedules:
Included
Risk considerations:
Adverse effects; withdrawal effects; opioid co-prescribing risks
Geographic context:
United Kingdom
Evidence sources:
Cochrane Reviews; NICE guidance; Summary of Product Characteristics
Year:
2023
Region / city:
UK
Topic:
Tapering regimen for benzodiazepine withdrawal
Document type:
Medical guideline
Organization / institution:
NHS Wales
Author:
Not specified
Target audience:
Healthcare professionals
Period of validity:
Not specified
Approval date:
Not specified
Date of amendments:
Not specified
Note:
Year
Year:
2024
Region / City:
Middletown
Theme:
Condominium Regulations
Document Type:
Governing Rules
Organization / Institution:
Council of Co-owners of Dorsey Station Condominiums
Author:
Board of Administration of the Council of Co-owners
Target Audience:
Dorsey Station Condominium Property Owners
Effective Date:
September 24, 2024
Amendment Date:
September 24, 2024
Approval Date:
September 24, 2024
Year:
2023
Region / City:
North Somerset
Theme:
Health Care Services, Procurement
Document Type:
Procurement Regulation
Organization / Institution:
North Somerset Council
Author:
North Somerset Council
Target Audience:
Providers of health care services
Effective Period:
From 01/04/2026 to 31/03/2029
Approval Date:
Not specified
Amendment Date:
Not specified
Note:
Year
Year:
2021
Region / City:
United Kingdom
Subject:
Intellectual Property, Parallel Trade, Exhaustion Regime
Document Type:
Consultation Response Form
Organization:
Intellectual Property Office (IPO)
Author:
UK Government
Target Audience:
Businesses, Organizations, and Individuals involved in intellectual property
Period of validity:
N/A
Approval Date:
N/A
Amendment Date:
N/A
Date:
[Insert DD Month YYYY]
Jurisdiction:
Australia
Subject:
Tax File Number withholding obligations for closely held trusts
Document Type:
Advisory letter
Addressee:
[Insert Client Name]
Author:
[Insert name of Partner]
Relevant Authority:
Australian Taxation Office
Applicable Tax Year:
Year ended 30 June 2024
Withholding Rate:
47% (highest marginal tax rate plus Medicare levy)
Compliance Obligations:
PAYG withholding registration, annual TFN withholding report, annual payment summary, remittance of withheld amounts
Reporting Deadlines:
30 September, 14 October, 28 October
Penalties:
Administrative penalties for failure to withhold, remit or report
Year:
2023
Region / City:
England
Subject:
Health Care Services
Document Type:
Tender Invitation
Organization:
NHS England
Author:
NHS England
Target Audience:
Tenderers interested in providing mental health services
Effective Period:
2023-2025
Approval Date:
Not specified
Modification Date:
Not specified
Contract Type:
Service contract for National Staff Mental Health Support Service
Year:
2014
Region / City:
Ireland
Topic:
Legal Reforms, Court Structure
Document Type:
Legal Article
Author:
Eoin Martin B.L.
Target Audience:
Legal professionals, scholars, policymakers
Period of Application:
Ongoing since 28 October 2014
Approval Date:
28 October 2014
Date of Amendments:
N/A
Year:
2022
Region / City:
London
Subject:
SIRE 2.0 Inspection Program
Document Type:
Report
Organization / Institution:
Oil Companies International Marine Forum (OCIMF)
Author:
Sam Megwa, Programmes Director, OCIMF
Target Audience:
Vessel owners, operators, managers, crew, inspectors, recipients of inspection reports
Period of Effect:
Q2 2022
Approval Date:
18 January 2022
Date of Changes:
-
Year:
2022
Region / city:
Geneva
Topic:
Radio astronomy, broadband detectors, cosmic microwave background, millimetre-wave regime
Document type:
Report
Organization:
International Telecommunication Union (ITU)
Author:
ITU Study Group
Target audience:
Radiocommunication professionals, astronomers, researchers in cosmology
Effective period:
Not specified
Approval date:
2022
Amendment date:
Not specified
Context:
This document outlines the technical and operational characteristics of broadband, background-limited detectors used in radio astronomy, specifically for measuring the cosmic microwave background (CMB) in the millimetre-wave regime.
Type of Document:
Academic research article
Country:
Nigeria
Study Period:
1986–2020
Subject:
Value Added Tax (VAT), Poverty Reduction, Economic Growth
Methodology:
Simple Linear Regression Analysis
Authors:
Oladele O. Aluko; Ibrahim Musa; Yahaya Ismail
Affiliation:
Department of Economics, University of Abuja
Institution:
University of Abuja
VAT Rate Referenced:
7.5% (effective 1 February 2020; previously 5%)
Key Institutions Mentioned:
Federal Inland Revenue Service (FIRS); Central Bank of Nigeria
Keywords:
Value Added Tax (VAT); Poverty Reduction; Economic Growth; Tax Administration; Fiscal Policy
Year:
2026
Region / City:
Aalborg
Topic:
Digital Authoritarianism, Journalism, Political Regimes
Document Type:
Master Thesis
Organization / Institution:
Aalborg University
Author:
Martina Hrgović
Target Audience:
Scholars, Researchers, Journalists
Period of Validity:
January 6, 2026
Date of Approval:
January 6, 2026
Date of Changes:
None
Year:
2024
Note:
Region / City
Subject:
Missile Technology Control
Document Type:
Annex
Organization:
Missile Technology Control Regime
Approval Date:
14th March 2024