№ files_lp_3_process_7_085063
Laboratory instructional guide detailing the synthesis, purification, safety precautions, and analytical evaluation of aspirin through esterification and recrystallisation in an educational chemistry setting.
Title: Preparation of Aspirin
Document Type: Laboratory Guide
Subject: Chemistry
Topic: Synthesis of Aspirin
Chemical Reaction: Condensation of 2-hydroxybenzoic acid with ethanoic anhydride
Product: Aspirin (acetylsalicylic acid)
Educational Level: Pupil
Required Chemicals: 2-hydroxybenzoic acid; ethanoic anhydride; 85% phosphoric acid; ethanol; deionised water
Required Equipment: Conical flasks; measuring cylinders; beakers; thermometers; balance; hot plate; Buchner funnel and flask; water pump; oven; melting point apparatus
Safety Requirements: Use of eye protection (BS EN166 3); gloves; fume cupboard handling
Procedure Includes: Heating to 85°C; recrystallisation; filtration; drying; melting point determination
Analytical Methods: Determination of melting point; calculation of percentage yield
Price: 8 / 10 USD
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