№ lp_1_2_44374
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The document provides a detailed method for assessing the equivalence of pesticide batches with a focus on ecotoxicological studies, including Tier 1 and Tier 2 assessments of impurities.
Year: 2019
Region / City: European Union
Topic: Ecotoxicology, Pesticides
Document Type: Technical Report
Author: European Food Safety Authority (EFSA)
Target Audience: Scientists, Regulatory Bodies, Pesticide Manufacturers
Validity Period: Not specified
Approval Date: 2019
Amendment Date: Not specified
Price: 8 / 10 USD
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Data gap assessment for glufosinate under EFSA mandate SANTE.E.4/AN/et(2024)582485 pursuant to Regulation (EC) No 396/200
Year: 2024
Substance: Glufosinate-ammonium
Related substances: NAG, MPP, MPA
Regulatory framework: Regulation (EC) No 396/200, Article 43
Mandating authority: EFSA
Mandate reference: SANTE.E.4/AN/et(2024)582485
Document type: Regulatory scientific assessment
Subject area: Toxicology and risk assessment
Endpoints covered: ADME, acute toxicity, short-term toxicity, genotoxicity, long-term toxicity, reproductive toxicity, neurotoxicity, endocrine disrupting properties
Identified data gaps: Genotoxicity, endocrine disrupting properties, in vitro biotransformation, micronucleus testing, PBPK model transparency
Test guidelines referenced: OECD test guidelines
Species referenced: Rat, mouse, dog, rabbit, human
Modelling approach: Physiologically based pharmacokinetic (PBPK) modelling
Authors referenced: Dickschen, Görlitz, Hatz
Report referenced: M-534722-01-1
EFSA England Winter Challenge Big Fish Weymouth Saturday 10th January 2026
Year: 2026
Location: Weymouth, England
Event type: Fishing competition
Organizer: Weymouth Angling Society
Target audience: Anglers
Date of event: 10th January 2026
Rules: Catch & release for all fish except other fish over 5lb; one hook only; bait supplied (mackerel & squid)
Scoring system: Spurdog, Conger, all rays 5pts each; any other fish over 5lb 10pts; tie-breakers based on number of rays
Prizes: 1st, 2nd, 3rd for heaviest fish excluding Conger
Schedule: Boat draw and bait collection at Weymouth Angling Centre 6:30am; boats depart 8am; return 4pm; prize presentation 11th January 2026 at AGM
Parking: Cousens Quay, £6 for 24hrs, code 818180
Supporting Information File 1: Methods and Model Formulations for Estimating No-Effect Toxicity Concentrations in Ecotoxicology Simulation Studies
Field: Ecotoxicology
Document type: Supporting information file
Content type: Methodological appendix with model formulations and simulation data
Subject: Estimation of no-effect toxicity concentrations (NEC) and ECx metrics
Models described: NEC3param, NEC4param, ECxLinear, ECxExp, ECxSigmoidal, ECx4param, ECxWeibull1, ECxWeibull2
Software / framework: jagsNEC (Bayesian modelling approach)
Key parameters: τ (upper plateau / intercept), η (NEC), β (decay rate), δ (lower plateau), ω (EC50)
Methods included: Threshold models, sigmoidal decay models, Weibull models
Data type: Simulated toxicity and concentration–response data
Simulation design: Multiple sampling schemes with varying treatment levels, replicates, and binomial trials
Measured variable: Concentration–response relationships for toxicity effects
Chemical context: Weathered Ichthys condensate WAF expressed as Total Aromatic Hydrocarbons (µg/L TAH)
Biological context: Tropical marine species responses including A. millepora, S. variolaris, N. dorsatus, and A. amphitrite
Statistical approach: Bayesian model fitting with MCMC and DIC-based model weighting
Included materials: R functions for simulation data generation, model equations, simulation study tables, and figure of fitted concentration–response curves
Tables: Model weight comparison (Table S1); toxicity estimates and effects across simulation designs (Table S2)
Figure: Concentration–response relationships with Bayesian NEC-sigmoidal model fits (Figure S1)
Supporting Information to Terrestrial isopods as model organisms in soil ecotoxicology: a review
Year: 2017
Region / Country: Netherlands, Portugal, Slovenia
Subject: Soil ecotoxicology, terrestrial isopods, chemical toxicity
Document type: Supplementary information
Institution: Vrije Universiteit Amsterdam; University of Aveiro; University of Ljubljana
Authors: Cornelis A.M. van Gestel, Susana Loureiro, Primoz Zidar
Target audience: Environmental scientists, ecotoxicologists
Data type: Literature review, experimental data summary
Chemicals studied: Cadmium, zinc, imidacloprid, thiacloprid, dimethoate, abamectin, doramectin, chlorantraniliprole, bisphenol A, vinclozolin, endosulfan, parathion
Isopod species: Porcellio scaber, Porcellio dilatatus, Porcellionides pruinosus, Armadillidium vulgare
Exposure types: Soil, food
Endpoints measured: Survival, reproduction, energy reserves, enzyme activity, protein expression, locomotor function, sublethal effects
Contextual description: Supplementary data compiling experimental results and literature references on the effects of various chemicals on terrestrial isopods, including toxicity endpoints and exposure conditions.
Topics: 2019EN-1673 EFSA ecotoxicology