№ lp_1_2_32967
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Regulatory data gap evaluation outlining missing or insufficient toxicological studies and methodological limitations for glufosinate-ammonium and its metabolites within an EFSA pesticide residue review context.
Year: 2024
Substance: Glufosinate-ammonium
Related substances: NAG, MPP, MPA
Regulatory framework: Regulation (EC) No 396/200, Article 43
Mandating authority: EFSA
Mandate reference: SANTE.E.4/AN/et(2024)582485
Document type: Regulatory scientific assessment
Subject area: Toxicology and risk assessment
Endpoints covered: ADME, acute toxicity, short-term toxicity, genotoxicity, long-term toxicity, reproductive toxicity, neurotoxicity, endocrine disrupting properties
Identified data gaps: Genotoxicity, endocrine disrupting properties, in vitro biotransformation, micronucleus testing, PBPK model transparency
Test guidelines referenced: OECD test guidelines
Species referenced: Rat, mouse, dog, rabbit, human
Modelling approach: Physiologically based pharmacokinetic (PBPK) modelling
Authors referenced: Dickschen, Görlitz, Hatz
Report referenced: M-534722-01-1
Price: 8 / 10 USD
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