№ files_lp_3_process_9_63622
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Supplementary statistical tables presenting distributions of CD4 and CD8 T cell and monocyte phenotypes in HIV-positive and HIV-negative participants and reporting their associations with pulmonary function measures using adjusted linear regression analyses.
Document type: Supplementary tables
Study population: HIV-positive (n=142) and HIV-negative (n=73) participants
Subgroup analysis: HIV-negative participants (n=71 with pre-; n=73 with post- measurements)
Measured variables: CD4 T cell phenotypes, CD8 T cell phenotypes, monocyte phenotypes
Phenotype categories: Differentiation, Activation Profiles, Inflammation/Exhaustion Profiles, Senescence Profiles
Monocyte subsets: Classical, Intermediate, Non-Classical
Pulmonary function measures: FEV1, FVC, FEV1/FVC, DLCO
Statistical methods: Two-sample t-test; linear regression models with adjustment for HBV infection, HCV infection, smoking pack-years, body-mass index, marijuana use, crack cocaine use, injection drug use, tuberculosis, pneumonia
Data presentation: Median (IQR); standardized beta coefficients
Reference standards: NHANES III predicted lung function values
Significance thresholds: P < 0.05 with Bonferroni correction (P=0.05/112)
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Distinct circulating monocyte profiles in chronic cannabis users compared to cocaine users without a changes in plasma levels of proinflammatory cytokines and LPS levels
Year: 2023
Region / City: Charleston, USA
Topic: Immunology, Substance Abuse, Pharmacology
Document Type: Research Article
Organization / Institution: Medical University of South Carolina, Ralph H. Johnson VA Medical Center, University of North Carolina at Chapel Hill, Aaron Diamond AIDS Research Center
Author: Douglas Johnson, Zhenwu Luo, Sylvia Fitting, Zizhang Sheng, Wei Jiang
Target Audience: Researchers, Healthcare Professionals, Academics
Study Period: 2023
Approval Date: 2023
Changes Date: None
Keywords: Chronic cannabis use, cocaine use, monocytes, cytokines, immune system, substance abuse, microbial translocation, systemic inflammation
Note: Abstract
Monocyte Chemoattractant Protein-1 from a Conditioned Medium of Bone Marrow-Derived Mesenchymal Stem Cells Promotes Bone Regeneration by Enhancing Macrophage Phenotype Switching
Year: 2026
Region / City: Not specified
Topic: Bone Regeneration, Macrophage Phenotype Switching
Document Type: Research Article
Organization / Institution: Not specified
Author: Not specified
Target Audience: Researchers, Medical Professionals
Duration: Not specified
Approval Date: Not specified
Modification Date: Not specified
Directory for trans* individuals undergoing Hormone Replacement Therapy (HRT) and HIV-positive refugees Access to medical support
Year: 2023
Region / City: Austria
Theme: Healthcare support for trans* individuals and HIV-positive refugees
Document type: Directory
Organization: Multiple healthcare providers
Author: Not specified
Target audience: Trans* individuals undergoing HRT, HIV-positive refugees
Period of validity: Ongoing
Date of approval: Not specified
Date of changes: Not specified
Haematologic and Haemostatic Profiles of HIV-Positive Subjects on Two Antiretroviral Regimens in Port Harcourt, Nigeria
Country: Nigeria
City / Region: Port Harcourt, Rivers State
Research Location: Rivers State University Teaching Hospital (RSUTH); University of Port Harcourt Teaching Hospital (UPTH)
Subject Area: Hematology; Hemostasis; HIV/AIDS Research
Type of Document: Scientific Research Article
Study Population: Human Immunodeficiency Virus-Positive subjects aged 20–79 years
Sample Size: 150 participants
Study Groups: First-line regimen (Abacavir Lamivudine Dolutegravir); Second-line regimen (Tenofovir Lamivudine Dolutegravir); Naïve HIV-positive control group
Medical Conditions Studied: Human Immunodeficiency Virus (HIV); hematologic abnormalities; haemostatic abnormalities
Laboratory Methods: Sysmex XP-300 Automated Haematology Analyzer; Enzyme Linked Immunosorbent Assay (ELISA); Prothrombin Time (PT); Activated Partial Thromboplastin Time (APTT)
Statistical Analysis: Student’s independent t-test; Analysis of Variance (ANOVA); Microsoft Office Excel 2007; GraphPad Prism 6.2
Measured Parameters: White blood cell count; lymphocyte count; haemoglobin; neutrophil-to-lymphocyte ratio; prothrombin time; activated partial thromboplastin time; D-dimer levels
Study Objective: Assessment of hematologic and haemostatic profiles in HIV-positive subjects receiving different antiretroviral regimens
Keywords: Hematologic; Haemostatic; Human Immunodeficiency Virus-Positive Subjects; Antiretroviral regimen; First-line; Second-line; Naïve
Topics: HIV-Negative Monocyte HIV-positive