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Research article examining the impact of chronic cannabis and cocaine use on monocyte profiles and systemic inflammation, revealing substance-specific immune effects without concurrent changes in plasma cytokine levels or LPS translocation.
Year: 2023
Region / City: Charleston, USA
Topic: Immunology, Substance Abuse, Pharmacology
Document Type: Research Article
Organization / Institution: Medical University of South Carolina, Ralph H. Johnson VA Medical Center, University of North Carolina at Chapel Hill, Aaron Diamond AIDS Research Center
Author: Douglas Johnson, Zhenwu Luo, Sylvia Fitting, Zizhang Sheng, Wei Jiang
Target Audience: Researchers, Healthcare Professionals, Academics
Study Period: 2023
Approval Date: 2023
Changes Date: None
Keywords: Chronic cannabis use, cocaine use, monocytes, cytokines, immune system, substance abuse, microbial translocation, systemic inflammation
Note: Abstract
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Supplementary Tables 1–5. Percentages of T Cell and Monocyte Phenotypes and Their Associations with Pulmonary Function Measures in HIV-Positive and HIV-Negative Participants
Document type: Supplementary tables
Study population: HIV-positive (n=142) and HIV-negative (n=73) participants
Subgroup analysis: HIV-negative participants (n=71 with pre-; n=73 with post- measurements)
Measured variables: CD4 T cell phenotypes, CD8 T cell phenotypes, monocyte phenotypes
Phenotype categories: Differentiation, Activation Profiles, Inflammation/Exhaustion Profiles, Senescence Profiles
Monocyte subsets: Classical, Intermediate, Non-Classical
Pulmonary function measures: FEV1, FVC, FEV1/FVC, DLCO
Statistical methods: Two-sample t-test; linear regression models with adjustment for HBV infection, HCV infection, smoking pack-years, body-mass index, marijuana use, crack cocaine use, injection drug use, tuberculosis, pneumonia
Data presentation: Median (IQR); standardized beta coefficients
Reference standards: NHANES III predicted lung function values
Significance thresholds: P < 0.05 with Bonferroni correction (P=0.05/112)
Monocyte Chemoattractant Protein-1 from a Conditioned Medium of Bone Marrow-Derived Mesenchymal Stem Cells Promotes Bone Regeneration by Enhancing Macrophage Phenotype Switching
Year: 2026
Region / City: Not specified
Topic: Bone Regeneration, Macrophage Phenotype Switching
Document Type: Research Article
Organization / Institution: Not specified
Author: Not specified
Target Audience: Researchers, Medical Professionals
Duration: Not specified
Approval Date: Not specified
Modification Date: Not specified
ASSESSMENT OF INFLAMMATORY CYTOKINES AND C-REACTIVE PROTEIN IN PREECLAMPTIC WOMEN IN NASARAWA, NIGERIA
Journal Name: Asian Research Journal of Gynaecology and Obstetrics
Manuscript Number: Ms_ARJGO_140463
Type of Article: ORIGINAL RESEARCH ARTICLE
Authors: Not specified
Reviewer: Monisha C, Dr Rela Institute and Medical Center, India
Region: Nasarawa, Nigeria
Research Focus: Inflammatory markers and preeclampsia
Ethical Considerations: Not specified
Language: English
Target Audience: Medical and scientific community
Date of Submission: Not specified
Abstract Quality: Comprehensive
Scientific Validity: Confirmed
References: Sufficient and recent
Supplemental Table 1: Pro- and anti-inflammatory cytokines assayed but not detected at adequate levels for analyses in this sample of children with cerebral palsy during intrathecal baclofen pump implant surgery (T1) and at ITB pump refill visits (T2).
Year: 2026
Region / City: N/A
Topic: Cytokine analysis in children with cerebral palsy
Document Type: Table
Organization / Institution: N/A
Author: N/A
Target Audience: Researchers in the field of pediatric neurology and immunology
Period of Effect: N/A
Approval Date: N/A
Date of Changes: N/A
Description: A table presenting data on cytokine levels in children with cerebral palsy during two medical events, providing insight into pro- and anti-inflammatory cytokines detected during the study.
Topics: proinflammatory Monocyte cytokines