№ files_lp_4_process_1_37116
File format: docx
Character count: 2365
File size: 18 KB
Summary of updated NICE guidance for familial breast cancer outlining primary care roles, referral pathways, risk assessment, and interaction with secondary care for management and prophylactic treatments.
Year:
2023
Region:
United Kingdom
Topic:
Breast Cancer, Familial Risk
Document Type:
Clinical Guideline Summary
Organization:
National Institute for Health and Care Excellence (NICE)
Target Audience:
General Practitioners, Primary Care Staff
Level of Care:
Primary and Secondary Care
Key Recommendations:
Referral pathways, Family history assessment, Tamoxifen prescribing
Implementation Status:
Updated guideline with electronic template in progress
Relevant Clinical Areas:
Breast Units, Family History Clinics, Genetic Services
Screening:
NHS Breast Screening Programme, additional surveillance for high-risk women
Price: 8 / 10 USD
The file will be delivered to the email address provided at checkout within 12 hours.
The file will be delivered to the email address provided at checkout within 12 hours.
Don’t have cryptocurrency yet?
You can still complete your purchase in a few minutes:- Buy Crypto in a trusted app (Coinbase, Kraken, Cash App or any similar service).
- In the app, tap Send.
- Select network, paste our wallet address.
- Send the exact amount shown above.
The final amount may vary slightly depending on the payment method.
The file will be sent to the email address provided at checkout within 24 hours.
The product description is provided for reference. Actual content and formatting may differ slightly.
Year:
2023
Region / City:
United States
Topic:
Genetic Conditions, Familial Hypercholesterolemia
Document Type:
Template Letter
Organization / Institution:
N/A
Author:
N/A
Target Audience:
Family members of individuals diagnosed with FH
Effective Period:
N/A
Approval Date:
N/A
Modification Date:
N/A
Year:
2024
Region / City:
Florida, USA
Topic:
Criminal Law, Sexual Battery
Document Type:
Legal Instruction
Author:
Florida Legislature
Target Audience:
Legal professionals, judges, prosecutors, defense attorneys
Period of validity:
From 1987, with amendments through March 2024
Date of approval:
1987
Date of amendments:
December 21, 2022; March 8, 2024
Note:
Year
Theme:
Genetics, Medical Diagnostics
Document type:
Educational activity
Target audience:
Students, Educators
Year:
2023
Region / City:
Dorset
Theme:
Child Protection, Safeguarding
Document Type:
Terms of Reference
Organization:
Dorset Council, Dorset Police
Target Audience:
Professionals involved in child protection and safeguarding
Period of validity:
Ongoing
Approval Date:
September 2023
Date of Changes:
None
Year:
2020
Region / Institution:
University College London
Programme:
DPUK Work Package 5
Related Work Packages:
WP3 (UK Biobank), WP4 (1946 birth cohort), WP6
Thematic Area:
Neurodegenerative diseases and biomarkers
Diseases Covered:
Familial Alzheimer’s disease, Familial frontotemporal dementia, Huntington’s disease, Familial Parkinson’s disease (LRRK2)
Cohorts:
UCL FAD, DIAN, GENFI, Track HD, LRRK2 cohort
Type of Document:
Research programme summary and output report
Organ / Institution:
University College London
Collaborating Initiatives:
DIAN, GENFI, Track HD, UK Biobank
Main Biomarkers Studied:
Serum neurofilament light (NfL), plasma phospho-tau181, cortical mean diffusivity, PET imaging markers
Study Population:
Individuals with autosomal dominant inherited neurodegenerative diseases and non-mutation carrier siblings
Research Focus:
Presymptomatic to symptomatic disease progression and biomarker validation
Outputs:
Peer-reviewed publications and longitudinal cohort analyses
Authors:
Jasmine Gratton; Steve E Humphries; Marta Futema
Institutions:
Institute of Cardiovascular Science, Faculty of Population Health Sciences, University College London, London, United Kingdom; Cardiology Research Centre, Molecular and Clinical Sciences Research Institute, St George’s University of London, London, United Kingdom
Country:
United Kingdom
Data source:
UK Biobank
Study design:
Population-based cohort study
Subject:
Prevalence of FH-causing genetic variants and association with LDL-C levels across ancestry groups
Population:
European, South Asian, and African ancestry participants
Sample size:
140,439 European; 4,067 South Asian; 3,906 African participants with lipid and whole exome sequencing data
Genes analysed:
LDLR; APOB; PCSK9
Methods:
Principal component analysis; whole exome sequencing; variant classification using ACMG guidelines
Outcome measures:
Prevalence of pathogenic and likely pathogenic FH variants; LDL-C concentration adjusted for statin use; prevalence and incidence of coronary heart disease
Period of data collection:
2006–2010
Ethical approval:
Conducted under approved UK Biobank application 40721
Type of document:
Scientific research article
Year:
2023
Region / City:
Denmark
Topic:
Familial Hypercholesterolemia, Lipid Profiles, Cardiovascular Risk
Document Type:
Supplementary Data / Research Tables
Institution:
Danish National Patient Registry, Danish Familial Hypercholesterolemia Registry
Authors:
Hedegaard BS, Bork CS, Kanstrup HL, Besseling J, Visseren F, et al.
Target Audience:
Researchers and clinicians in cardiology and genetics
Data Collection Period:
Up to 2023
Methods:
Clinical data validation, genetic testing, lipid-lowering treatment assessment
Abbreviations Used:
LDL-C, Lp(a), FH, DLCN, DNPR, LDLR, ApoB, PCSK9
Data Validity:
Positive predictive values and sensitivity for DLCN components
Follow-up:
6±2 months post-diagnosis
Genetic Analysis:
Pathogenic variants in LDLR, ApoB, PCSK9
Year:
2022
Region / city:
UK
Theme:
Diabetes care, structured education
Document type:
Report
Organization / institution:
National Institute for Health and Care Excellence (NICE)
Author:
National Institute for Health and Care Excellence
Target audience:
Healthcare professionals, CCGs
Validity period:
2014/15 - ongoing
Approval date:
March 2022
Review date:
March 2023
Year:
2005
Region / City:
United Kingdom
Topic:
Healthcare, Bioethics, Public Health
Document Type:
Guidance
Organization / Institution:
National Institute for Health and Clinical Excellence (NICE)
Author:
National Institute for Health and Clinical Excellence (NICE) Board
Target Audience:
Those involved in developing or revising NICE guidance, NICE’s advisory bodies, stakeholders, and the general public
Period of Effectiveness:
Ongoing
Approval Date:
2005
Date of Changes:
Not specified
Year:
2023
Region / City:
United States
Theme:
Cybersecurity, Workforce Development
Document Type:
Interview
Organization:
U.S. Department of Homeland Security (DHS)
Author:
Gregory Bird
Target Audience:
Cybersecurity professionals, Human Resources in cybersecurity
Period of Action:
Ongoing
Approval Date:
Not provided
Date of Changes:
Not provided
Year:
1985
Region / City:
CEPT countries
Topic:
Radio Amateur Licensing
Document Type:
Recommendation
Organ / Institution:
CEPT
Author:
CEPT
Target Audience:
Radio Amateurs, CEPT administrations, non-CEPT administrations
Period of Validity:
Ongoing
Date of Approval:
1985
Date of Amendments:
May 2016, February 2023, June 2022
Note:
Context
Date:
September 25, 2024
Year:
2024
Region / City:
Geneva
Topic:
Intellectual Property
Document Type:
Report
Organization:
WIPO
Target Audience:
WIPO Member States
Period of validity:
From July 9 to 17, 2024
Date of adoption:
Not specified
Date of amendments:
Not specified
Year:
2019
Region / City:
United Kingdom
Topic:
Chronic Obstructive Pulmonary Disease (COPD), Oxygen Saturation
Document Type:
Guidance
Organization:
National Institute for Health and Care Excellence (NICE)
Author:
NICE
Target Audience:
General practitioners, healthcare professionals
Period of Validity:
Not specified
Approval Date:
August 2019
Date of Last Update:
N/A
Year:
2022
Region / City:
England
Theme:
Health Inequalities
Document Type:
Final Report
Organization / Institution:
National Institute for Health and Care Excellence (NICE)
Author:
NICE
Target Audience:
General public, policymakers, health professionals
Period of Validity:
2021-2026
Approval Date:
January 2022
Date of Changes:
None
Year:
2021
Region / city:
N/A
Subject:
Clinical guideline
Document type:
Indicator guidance
Organization / institution:
National Institute for Health and Care Excellence (NICE)
Author:
N/A
Target audience:
Healthcare professionals, Clinical commissioning groups
Period of validity:
N/A
Approval date:
August 2021
Date of updates:
N/A
Year:
2021
Region / City:
San Antonio, Texas
Theme:
Cybersecurity Workforce Development
Document Type:
Interview
Institution:
National Initiative for Cybersecurity Education (NICE)
Author:
Rodney Petersen, Chris Knox
Target Audience:
Cybersecurity professionals, organizational managers
Period of Validity:
Not specified
Approval Date:
Not specified
Date of Modifications:
Not specified
Year:
2019
Region / city:
England
Topic:
Heart failure diagnosis, clinical guidelines
Document type:
Guidance
Organization / institution:
National Institute for Health and Care Excellence (NICE)
Author:
National Institute for Health and Care Excellence (NICE)
Target audience:
Healthcare professionals, general practitioners
Period of validity:
N/A
Approval date:
August 2019
Date of updates:
N/A
Year:
2019
Region / City:
England
Topic:
Heart Failure, Treatment, Cardiovascular Disease
Document Type:
Guidance
Organization:
National Institute for Health and Care Excellence (NICE)
Author:
National Institute for Health and Care Excellence
Target Audience:
General practitioners, healthcare providers
Period of validity:
Ongoing
Approval Date:
August 2019
Date of Changes:
N/A
Year:
2019
Region / city:
United Kingdom
Topic:
Mental health, Alcohol use
Document type:
Guidance
Organization / institution:
National Institute for Health and Care Excellence (NICE)
Author:
National Institute for Health and Care Excellence
Target audience:
Healthcare professionals
Period of validity:
N/A
Approval date:
August 2019
Date of last update:
N/A
Year:
2013
Region / City:
United Kingdom
Topic:
Patient group directions, healthcare professionals, NICE guidance
Document Type:
Framework
Organization / Institution:
National Institute for Health and Care Excellence
Author:
National Institute for Health and Care Excellence
Target Audience:
Health professionals, commissioners, and healthcare providers
Effective Period:
From August 2013
Approval Date:
August 2013
Last Updated:
January 2018
Date of Amendments:
January 2018