№ lp_1_2_45023
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The document is a NICE indicator guidance outlining the need for oxygen saturation monitoring in patients with very severe COPD, specifically in the context of long-term oxygen therapy for those with hypoxaemia.
Year:
2019
Region / City:
United Kingdom
Topic:
Chronic Obstructive Pulmonary Disease (COPD), Oxygen Saturation
Document Type:
Guidance
Organization:
National Institute for Health and Care Excellence (NICE)
Author:
NICE
Target Audience:
General practitioners, healthcare professionals
Period of Validity:
Not specified
Approval Date:
August 2019
Date of Last Update:
N/A
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Document type:
Supplementary materials
Study type:
Randomized controlled trial
Trial name:
iMODIPONV
Medical field:
Anesthesiology
Clinical focus:
Postoperative nausea and vomiting after hysterectomy
Primary variable:
Muscular tissue oxygen saturation
Population:
Posthysterectomy patients
Study design:
Multicenter
Participating institutions:
University and provincial hospitals
Countries involved:
China, United States
Committees:
Steering Committee, Quality Committee, Data Safety Monitoring Board
Data included:
Site investigators, coordinators, hospital participation, treatment assignment, randomization errors
Analyses:
Sensitivity analyses, multivariable logistic regression
Supplementary content:
Figures and tables
Source type:
Supplement to a peer-reviewed clinical trial publication
Name:
Ogunleye Precious Aderayo
Matric Number:
16/MHS02/034
Course Code:
NSC 414
Course Title:
Research in Nursing
Type of Document:
Academic Assignment
Discipline:
Nursing
Subject Area:
Qualitative Research Methodology
Key Topics:
Trustworthiness, Credibility, Transferability, Confirmability, Dependability, Data Saturation, Content Analysis
Educational Level:
Undergraduate
Institutional Context:
Nursing Education
Assessment Type:
Written Coursework
Year:
2024
Region:
United States
Subject:
Healthcare service provider distribution and utilization
Document Type:
Technical Guide
Organization:
Centers for Medicare & Medicaid Services (CMS)
Intended Audience:
Healthcare providers, researchers, policy analysts
Data Source:
Medicare Fee-for-Service (FFS) claims, CMS Integrated Data Repository (IDR)
Update Frequency:
Annual for state and county data starting 2024, quarterly prior
Geographic Scope:
State, county, Core-Based Statistical Area (CBSA)
Services Covered:
Ambulance (emergency and non-emergency), Home Health, Skilled Nursing Facilities, IDTF Part A
Methodology:
Zip code-based beneficiary location, provider claims-based service area
Exclusion Criteria:
Beneficiaries or providers with insufficient claims, CBSA and county thresholds
Reference Period:
12 months
Purpose:
Monitor market saturation, identify patterns of service use, support research and service planning
Guidance:
Technical specifications for data interpretation and analysis
Year:
2017–2018
Region / City:
Ilorin, Kwara State, Nigeria
Topic:
Hematology / Iron Status
Document Type:
Original Research Article
Institution:
University of Ilorin Teaching Hospital
Author:
Not specified
Target Population:
Healthy Nigerian adults aged 18–70
Sample Size:
112 participants
Methods:
Cross-sectional study, full blood count, ELISA for serum ferritin and soluble transferrin receptor, TSAT calculation
Inclusion Criteria:
Adults aged 18–70 with consent
Exclusion Criteria:
Hematinics use, blood donors, recent transfusion, febrile illness
Statistical Analysis:
SPSS version 22.0, p-value < 0.05
Reference Ranges Established:
Serum ferritin 20.0–218.4 ng/ml, TSAT 21.5–47.4%, sTfR 8.8–26.9 nmol/L
Year:
2026
Region / City:
Beijing, China
Subject:
Biochemistry, Cellular Stress, Inflammation
Document Type:
Supplementary Information
Institution:
Peking University, College of Urban and Environmental Sciences
Authors:
Wenxin Hu, Qiyue Kang, Chenhao Zhang, Haojia Ma, Chenke Xu, Yi Wan, Jianying Hu
Correspondence:
Dr. Jianying Hu, [email protected]
Experimental Models:
In vitro cellular assays, qRT-PCR analysis
Chemicals:
Triphenyl phosphate (TPHP), DMEM-F12, Fetal bovine serum, Trizol
Analytical Methods:
Mass spectrometry, PCR primers listed, fluorescence assays
Purpose:
Investigation of phospholipid saturation effects on endoplasmic reticulum stress and inflammatory response
Year:
2024
Region / City:
Global
Topic:
Chronic Obstructive Pulmonary Disease (COPD) Management
Document Type:
Research Study
Organization / Institution:
Various international medical organizations
Authors:
Schrijver J, Lenferink A, Brusse-Keizer M, et al.
Target Audience:
Healthcare professionals, researchers, policymakers
Period of Validity:
N/A
Approval Date:
N/A
Date of Changes:
N/A
Year:
2023
Region / city:
Australia
Type of document:
Pharmaceutical submission / Public Summary Document
Regulatory authority:
Therapeutic Goods Administration (TGA)
Submitted by:
Generic Health Pty Ltd
Product:
Tiotropium Lupin 18 microgram powder for inhalation, LupinHaler device
Indication:
Chronic obstructive pulmonary disease (COPD)
Previous PBS listing:
Spiriva 18 microgram powder for inhalation, HandiHaler device
Submission type:
Category 4 (cost-minimisation comparison)
PBS item code:
8626BMP,NP
Maximum quantity:
1 pack, 30 units
Prescriber type:
Nurse Practitioners, Medical Practitioners
Restriction type:
Restricted benefit
Administrative advice:
Not to be used in combination with LAMA/LABA or SAMA; adherence to current inhaler technique to be reviewed at each clinical visit; diagnosis requires spirometry confirmation
Year:
2023
Region / City:
England
Topic:
Healthcare, Quality Standards
Document Type:
Policy document
Organization / Institution:
NHS England
Author:
General Practice Specification and Extraction Service (GPSES), NHS England
Target Audience:
Healthcare providers, Medical professionals
Period of Validity:
2023-2024
Approval Date:
01/04/2023
Date of Amendments:
01/08/2023
Contextual Description:
Policy document outlining business rules for COPD management under the Quality and Outcomes Framework for NHS England.
Year:
Not specified
Region / City:
Not specified
Topic:
COPD, Medical Research Council score, Fibrinogen levels, Six-minute walking test, Medication costs, Probabilistic analysis
Document Type:
Scientific Analysis
Organization / Institution:
Not specified
Author:
Not specified
Target Audience:
Researchers, Healthcare professionals, Clinicians
Period of Action:
Not specified
Approval Date:
Not specified
Date of Changes:
Not specified
Year:
2023
Country:
China
Ethics Approval Number:
2023KYLL014
Scientific Field:
Genetic epidemiology
Research Topic:
Causal relationship between chronic obstructive pulmonary disease and lung adenocarcinoma
Study Design:
Two-sample Mendelian randomization study
Document Type:
Reporting checklist
Exposure:
Chronic obstructive pulmonary disease (COPD)
Outcome:
Lung adenocarcinoma (LUAD)
Data Sources:
GWAS dataset ebi-a-GCST90018807; GWAS dataset ebi-a-GCST004744; TCGA; GEO datasets GSE116959 and GSE76925
Sample Size:
57 LUAD patients, 11 healthy controls, 111 COPD cases, 40 smoking controls
Key Biomarkers:
FCRLA, GREM1, MMP9
Statistical Methods:
Inverse variance weighting (IVW), MR Egger, MR-PRESSO, LASSO regression, false discovery rate correction
Software:
R version 4.2.1; TwoSampleMR package; ggplot2
Diagnostic Criteria:
COPD defined by spirometry (FEV1/FVC < 0.7); LUAD confirmed by histopathology
Genetic Variant Selection Criteria:
Genome-wide significance threshold p < 5 × 10⁻⁸; LD pruning r² < 0.01
Core Mendelian Randomization Assumptions:
Relevance, independence, exclusion restriction
Document type:
Clinical correspondence letter
Medical topic:
COPD and bronchiectasis management
Medication:
Azithromycin
Purpose:
Recommendation to initiate azithromycin therapy to reduce exacerbations
Sender role:
Respiratory specialist
Recipient role:
General Practitioner
Patient category:
Patients with COPD or bronchiectasis experiencing exacerbations
Clinical objective:
Reduction in number of exacerbations within a 12-month period
Review schedule:
6 months after treatment initiation and additional follow-up months as specified
Prescribing status:
Amber Recommended
Prescribing guidance source:
Pan-Mersey Area Prescribing Committee
Response requirement:
GP confirmation or refusal within 14 days
Sections included:
Treatment dose and frequency, indication, review plan, GP decision section
Year:
2010
Organization:
Key Medical Resources, Inc.
Author:
Terry Rudd, RN, MSN
Type of Document:
Educational self-study module
Target Audience:
Nurses and healthcare professionals
Location:
Rancho Cucamonga, California, USA
Continuing Education Hours:
15.0
Certification:
California Board of Registered Nursing CEP#15122
Format:
Self-study with exam and evaluation form
Content Focus:
Asthma, COPD, respiratory assessment, lung function, pharmacology
Year:
2021
Study:
Global Burden of Disease Study 2021 (GBD 2021)
Topic:
Epidemiological modeling and data sources for COPD incidence and mortality
Document type:
Technical nomenclature and methodological description
Field:
Epidemiology and public health
Model:
Age–Period–Cohort (APC) model
Data source system:
Global Health Data Exchange (GHDx)
Database:
Causes of Death (CoD) database
Modeling tools:
DisMod-MR; MR-BRT (Bayesian regularized model with temporal smoothing)
Geographic coverage:
204 countries and territories
Health condition:
Chronic Obstructive Pulmonary Disease (COPD)
Data source types:
surveys, censuses, vital registration, surveillance systems, cancer registries, police records, sibling history, survey/census data, minimally invasive tissue sample diagnoses
Reference parameters:
reference age group (a0), reference period (p0), reference cohort (c0)
Statistical measures:
Net Drift, Age Deviations, Period Deviations, Cohort Deviations, Longitudinal Age Curve, Period Rate Ratios, Cohort Rate Ratios, Local Drifts
Data access platform:
Global Health Data Exchange citation tool
File format available:
CSV metadata export
Outlier criteria:
exclusion of implausible values, conflicts with age or temporal patterns, and inconsistencies with comparable data sources
Year:
2026
Region / City:
Multicenter, unspecified locations
Topic:
Chronic Obstructive Pulmonary Disease
Document Type:
Clinical Study Supplement
Organization / Institution:
Not specified
Author:
Not specified
Target Audience:
Clinical researchers and healthcare professionals
Study Phase:
Not specified
Inclusion Criteria:
Adults aged 40–80 with COPD, stable maintenance therapy, capable of performing spirometry and following study procedures
Exclusion Criteria:
Recent severe infections or surgeries, significant comorbidities, prohibited medication use, pregnancy or breastfeeding, recent participation in other trials
Prohibited Medications:
Systemic or inhaled corticosteroids, certain antibiotics, leukotriene inhibitors, theophylline, PDE4 inhibitors, terbutaline, nebulized COPD medications, oral β2-agonists
Study Visits:
Screening (visit 1), baseline and dosing (visit 2), mid-study assessment (visit 3), end-of-treatment assessment (visit 4), follow-up call post-treatment
Assessment Tools:
CAT, mMRC Dyspnea Scale, spirometry, vital signs, physical examination
Treatment Duration:
12 weeks
Compliance Monitoring:
Dispensed medication retrieval and assessment at visits 3 and 4
Year:
2010–2011
Region:
United Kingdom, England
Subject:
Telehealth, Chronic Obstructive Pulmonary Disease (COPD), Health Economics
Document type:
Research Study / Pilot Programme Report
Organization:
National Health Service Direct (NHSD)
Authors:
Not specified
Target population:
Patients with chronic obstructive pulmonary disease (COPD)
Study sites:
Two Primary Care Trusts (PCT1, PCT2)
Participants:
321 enrolled, 227 included in final analysis
Intervention:
Remote patient monitoring / telehealth
Outcome measures:
Cost-effectiveness, resource utilization, hospital admissions, length of stay
Data collection period:
12 months before, immediately before, and during monitoring
Keywords:
telehealth, telemedicine, cost-effectiveness, remote patient monitoring
Year:
2018
Region / city:
Regional Victoria
Topic:
Pathophysiology, Pharmacology, COPD, Pneumonia
Document type:
Case report
Organization / institution:
CRICOS Provider No. 00103D
Author:
Not specified
Target audience:
Healthcare professionals, Medical students
Action period:
Not specified
Approval date:
Not specified
Modification date:
Not specified
Year:
2026
Region:
West Yorkshire, UK
Subject:
Health communication / Patient engagement
Document type:
Template messages
Organization:
West Yorkshire Health Service
Target audience:
Patients with Asthma or COPD, parents/carers of children with Asthma
Platforms referenced:
Google Play, Apple App Store
Conditions addressed:
Asthma, COPD
Message length:
Short (≤160 characters), Long (≤300 characters)
Year:
2022
Region / city:
UK
Theme:
Diabetes care, structured education
Document type:
Report
Organization / institution:
National Institute for Health and Care Excellence (NICE)
Author:
National Institute for Health and Care Excellence
Target audience:
Healthcare professionals, CCGs
Validity period:
2014/15 - ongoing
Approval date:
March 2022
Review date:
March 2023
Year:
2005
Region / City:
United Kingdom
Topic:
Healthcare, Bioethics, Public Health
Document Type:
Guidance
Organization / Institution:
National Institute for Health and Clinical Excellence (NICE)
Author:
National Institute for Health and Clinical Excellence (NICE) Board
Target Audience:
Those involved in developing or revising NICE guidance, NICE’s advisory bodies, stakeholders, and the general public
Period of Effectiveness:
Ongoing
Approval Date:
2005
Date of Changes:
Not specified
Year:
2023
Region / City:
United States
Theme:
Cybersecurity, Workforce Development
Document Type:
Interview
Organization:
U.S. Department of Homeland Security (DHS)
Author:
Gregory Bird
Target Audience:
Cybersecurity professionals, Human Resources in cybersecurity
Period of Action:
Ongoing
Approval Date:
Not provided
Date of Changes:
Not provided