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Administrative biosafety compliance record used to formally document the completion of a research project and the inactivation of its Institutional Biosafety Committee protocol involving recombinant or synthetic nucleic acids and other biohazardous materials.
Organization: Institutional Biosafety Committee (IBC), Ann & Robert H. Lurie Children’s Hospital of Chicago
Document Type: Administrative Form
Purpose: Inactivation of an approved biosafety research protocol after project completion
Subject Area: Biosafety and Biohazardous Research Oversight
Related Activities: Research involving recombinant and synthetic nucleic acid molecules and biohazardous materials
Submission Method: E-mail submission to [email protected]
Responsible Role: Principal Investigator (PI)
Compliance Reference: NIH Guide for the shipment and transfer of recombinant and synthetic nucleic acids
Key Declarations: Confirmation of project completion, biosafety compliance, disposal of biohazards, and proper storage of biological agents
Required Fields: Date of report, biosafety registration number, protocol title, PI name, PI email, investigator signature, date
Approval Authority: Institutional Biosafety Committee
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Biosafety Registration for Research Involving Recombinant and Synthetic Nucleic Acid Molecules and Biohazardous Materials
Note: Year
Subject: Biosafety, Recombinant Nucleic Acids, Synthetic Nucleic Acids, Biohazardous Materials
Document Type: Registration Form
Institution: Stanley Manne Children’s Research Institute, Ann & Robert H. Lurie Children’s Hospital of Chicago
Target Audience: Researchers conducting experiments involving recombinant or synthetic nucleic acids or biohazardous materials
Guidance for Thermal Inactivation of Hepatitis A virus in Berries
Year: 2015
Region / city: Australia, New Zealand
Topic: Hepatitis A virus inactivation in berries
Document type: Guideline
Organization: Food Standards Australia New Zealand, Ministry for Primary Industries
Author: FSANZ Risk Assessment (Microbiology), Ministry for Primary Industries
Target audience: Food manufacturers, food safety professionals
Period of validity: Not specified
Approval date: December 2015
Date of changes: Not specified
Principle and Procedure for AET Treatment of Red Cells for Kell Antigen Inactivation
Document type: Laboratory procedure
Subject area: Immunohematology
Focus antigens: Kell system antigens and selected HTLA antigens
Chemical agent: 2-aminoethylisothiouronium bromide (6% AET)
Specimen type: EDTA anticoagulated whole blood
Materials and equipment: Cell washer, serological centrifuge, microscope, water bath or heating block at 37°C
Reagents: Phosphate buffered saline, 0.9% saline, anti-IgG, IgG-coated cells, anti-K or anti-k
Quality control: Verification of Kell antigen destruction using known anti-K or anti-k
Incubation conditions: 37°C for 20 minutes
Storage conditions: Treated cells stored in Alsevers solution for up to 7 days
Test methods: Antiglobulin testing, LISS-LIDAT methods
Interpretation framework: Comparative reactivity of treated versus untreated red cells
Document number: SP.009
Revision date: September 1, 2014
References: Judd’s Methods in Immunohematology; AABB Technical Manual, 17th edition
Instructions for Calculating Log Inactivation of Giardia Cysts (also known as “CT Calculations”)
Year: 2018
Region / City: United States
Topic: Water Treatment, Giardia Cyst Inactivation
Document Type: Instruction Manual
Organization / Institution: Public Water System
Author: Not specified
Target Audience: Certified operators at surface water treatment plants
Effective Period: Ongoing
Approval Date: Not specified
Modification Date: Not specified
Account Inactivation Notice from Washtenaw Library for the Blind and Print Disabled
Year: 2025
Region / City: Washtenaw
Subject: Account Inactivation
Document Type: Notification Letter
Organization / Institution: Washtenaw Library for the Blind and Print Disabled
Author: WLBPD Staff
Target Audience: Library users
Period of Validity: Indefinite
Approval Date: 05/5/2025
Date of Changes: Not specified
The Greater Access and Impact with NAT (GAIN) Study: Improving HIV Diagnosis, Linkage to Care, and Prevention Services with HIV Point-of-Care Nucleic Acid Tests (NATs)
Note: Year
Topic: HIV Diagnosis, Linkage to Care, and Prevention Services
Document Type: Guide
Organization / Institution: CDC
Target Audience: HIV-positive individuals who participated in the GAIN study
The Greater Access and Impact with NAT (GAIN) Study: Improving HIV Diagnosis, Linkage to Care, and Prevention Services with HIV Point-of-Care Nucleic Acid Tests (NATs) Attachment 4d Acceptability Survey
Year: N/A
Region / City: N/A
Topic: HIV Diagnosis, HIV Prevention
Document Type: Survey
Organization / Institution: CDC
Author: N/A
Target Audience: Participants of the GAIN Study
Effective Period: N/A
Approval Date: N/A
Date of Changes: N/A
Biosafety Registration for Research Involving Recombinant and Synthetic Nucleic Acid Molecules and Biohazardous Materials
Note: Year
Subject: Biosafety, Recombinant Nucleic Acids, Synthetic Nucleic Acids, Biohazardous Materials
Document Type: Registration Form
Institution: Stanley Manne Children’s Research Institute, Ann & Robert H. Lurie Children’s Hospital of Chicago
Target Audience: Researchers conducting experiments involving recombinant or synthetic nucleic acids or biohazardous materials
Manuscript template and author guidelines for Nucleic Acids Research
Journal: Nucleic Acids Research
Type of document: Manuscript template
Intended audience: Authors submitting to the journal
Sections included: Abstract, Introduction, Materials and Methods, Results, Discussion, Graphical Abstract, Data Availability
Formatting requirements: Font, layout, file type, resolution, orientation
Authorship instructions: Guidelines for corresponding authors, joint authorship, present addresses, groups and consortia
Graphical abstract requirements: Size, file type, resolution, content specifications
Submission instructions: Removal of template instructions before submission
Content guidance: Title clarity, avoidance of jargon, abstract limitations
Source type: Academic journal manuscript template
Beginner’s Guide to the NIH Guidelines for Research Involving Recombinant or Synthetic Nucleic Acid Molecules
Year: 2026
Institution: National Institutes of Health (NIH)
Type of Document: Guidance / Regulatory Summary
Subject: Recombinant DNA (rDNA) and Synthetic DNA (sDNA) research
Author: NIH Office of Biotechnology Activities (OBA)
Target Audience: Researchers using NIH funds, Institutional Biosafety Committees
Scope: United States, applicable to institutions receiving NIH funding
Regulatory References: NIH Guidelines, CDC Select Agent Program, BMBL Manual
Compliance Requirements: Institutional Biosafety Committee (IBC) approval, RAC review, IRB approval for human research, adherence to biosafety and waste management protocols
Publication Date: 2026
Website Reference: http://osp.od.nih.gov/office-biotechnology-activities/biosafety/nih-guidelines
Manuscript template for Nucleic Acids Research
Year: 2023
Region / City: Global
Theme: Scientific Research, Nucleic Acids
Document Type: Manuscript Template
Organization / Institution: Nucleic Acids Research
Author: Not specified
Target Audience: Researchers, Scientists
Validity Period: Ongoing
Approval Date: Not provided
Modification Date: Not provided
Topics: Biohazardous Inactivation Nucleic