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The document provides a scientific review of bioactive peptides found in the saliva of medicinal leeches and their therapeutic roles in wound healing, vascular regeneration, and inflammation management.
Year:
2024
Region / City:
Global
Topic:
Leech therapy, bioactive peptides, wound care
Document type:
Scientific review
Organization / Institution:
Various academic researchers
Author:
Beena, Sheba, Abdulshukkoor
Target audience:
Medical professionals, researchers, students in pharmacology and biomedicine
Period of validity:
Ongoing research
Approval date:
2024
Date of changes:
Not specified
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The product description is provided for reference. Actual content and formatting may differ slightly.
Year:
2019
Region / City:
North America
Theme:
Veterinary Medicine, Feline Health
Document Type:
Research Article
Organization / Institution:
Hemopet
Author:
W. Jean Dodds
Target Audience:
Veterinary professionals, researchers, pet owners
Period of Validity:
Not specified
Approval Date:
1 August 2019
Modification Date:
Not specified
Keywords:
adverse food reactions, pet cats, saliva test
Year:
2023
Region / city:
Europe, Türkiye
Topic:
Medicinal leech species conservation, population dynamics, and threats
Document Type:
Case Study
Organization:
UNEP-WCMC, IUCN, Republic of Türkiye Ministry of Agriculture and Forestry
Author:
Utevsky et al., Sağlam et al.
Target audience:
Researchers, environmental conservationists, policy makers
Period of validity:
Not specified
Approval date:
Not specified
Date of changes:
2023
Year:
2017
Region / City:
Canterbury, England
Topic:
Music history, Post-rock
Document type:
Interview
Institution / Organization:
Falmouth University
Author:
Rupert Loydell
Interviewee:
Jeanette Leech
Target audience:
Readers interested in music history and post-rock
Keywords:
Jeanette Leech, post-rock, experimental rock, Talk Talk, dub, music history, acid folk
Period covered:
1960s–2000s
Publication references:
Seasons They Change (2010), Fearless (2017)
Document type:
Scientific research article
Field:
Peptide chemistry
Topic:
Solid-phase peptide synthesis and chelator incorporation
Chemical compound:
1-Hydroxypyridine-2-one (1,2-HOPO)
Derivative studied:
1,2-HOPO-4-COOH
Methodology:
Solid-Phase Peptide Synthesis (SPPS)
Resin:
Rink-amide resin
Protecting group:
Methyltrityl (Mtt)
Coupling reagent:
N,N’-diisopropylcarbodiimide (DIC)
Additive:
OxymaPure®
Cleavage reagent:
Trifluoroacetic acid (TFA)
Additional reagent:
Trifluoromethanesulfonic acid
Analytical method:
HPLC
Subject of study:
Incorporation of HOPO derivatives into Lys-containing peptides
Research focus:
Comparison of masked and unmasked N-hydroxy group during coupling
Year:
2023
Region / city:
Uganda
Subject:
Peptidomic analysis, host-defense peptides
Document type:
Research article
Author:
Laurent Coquet, Jolanta Kolodziejek, Thierry Jouenne, Norbert Nowotny, Jay D. King, J. Michael Conlon
Target audience:
Researchers in biomedicine, immunology, and zoology
Period of validity:
Not specified
Approval date:
Not specified
Modification date:
Not specified
Year:
2026
Organism:
Arabidopsis thaliana
Type of document:
Supplementary table
Content:
Protein annotation data with targeting peptides
Source table:
Table S3 used for confusion matrix
Protein classes:
SP, mTP, cTP, luTP
Data correction:
Corrected values and percentage shifts
Year:
2026
Research Area:
Immunology, Cancer Biology
Document Type:
Scientific Article Supplementary Data
Authors:
Guoying Ni et al.
Organ / Institution:
Not specified
Experimental Model:
TC-1 tumour-bearing mice
Treatments:
Caerin 1.1/1.9 peptides, P3, PD-1 blockade
Cell Types Studied:
Macrophages, B cells, NK cells, Dendritic cells, T cells
Methods:
Single-cell RNA sequencing, GO and KEGG enrichment analysis
Key Findings:
Modulation of immune cell populations and activation pathways in tumour microenvironment
Supplementary Figures:
13A-F, 14A-F
Year:
2026
Region / city:
Gwangju, Republic of Korea
Topic:
Antimicrobial peptides, Multidrug-resistant pathogens
Document type:
Research article
Organization / institution:
Chonnam National University, Chosun University
Author:
Byambasuren Ganbaatar, Sukumar Dinesh Kumar, Eun Young Kim, Naveen Kumar Radhakrishnan, Sungtae Yang, Song Yub Shin, Chul Won Lee
Target audience:
Researchers, professionals in microbiology and biochemistry
Period of validity:
Not specified
Approval date:
Not specified
Date of changes:
Not specified
Keywords:
Octopromycin, antimicrobial peptides, multidrug-resistant pathogens, biofilm activity, RP-HPLC, cell viability
Year:
Not specified
Laboratory / Facility:
SOPJin’s group, NSC 544
Instrument:
Shimadzu Nexera LC-40 HPLC
Document Type:
Standard Operating Procedure
Subject:
High-performance liquid chromatography operation and sample handling
Applicable Samples:
Water-soluble and UV-active peptides, compounds, dyes, and their conjugates
Excluded Samples:
DNA, RNA, proteins, polymers
Mobile Phase Composition:
MQ Water with 0.1% TFA (A) and acetonitrile with 0.1% TFA (B)
Detection Method:
PDA detector, wavelength range 190–800 nm
Column Types Mentioned:
C18 analytical and semi-preparative columns
Software:
LabSolutions
User Requirements:
Sample filtration with 0.22 µm filter, HPLC time booking in Microsoft Calendar
Operational Conditions:
Analytical flow rate ~1 mL/min; semi-prep flow rate 3–4 mL/min; column oven 35 °C
Safety and Handling Notes:
Degassing solvents, checking for leaks, stepwise pressure increase, cleaning injector and loop after use
Year:
2026
Region / City:
Bronx, NY, U.S.A.
Topic:
Anticancer research, peptides, algae
Document type:
Research article
Author:
Mary Biggs, Ipsita Banerjee
Target audience:
Researchers, biochemists, medical scientists
Period of validity:
N/A
Approval date:
N/A
Date of changes:
N/A
Year:
1994–2014
Region / Institution:
International / Various research institutions
Subject:
Peptide synthesis, chemoselective ligation, bioconjugation
Document type:
Scientific review / research summary
Authors:
Kent, Bertozzi, Bode, Dawson, Danishefsky, Hilvert, Tam, Lau, Macmillan
Target audience:
Researchers in chemistry and biochemistry
Key techniques:
Native Chemical Ligation (NCL), KAHA Ligation, Selenocysteine ligation, Homocysteine ligation, KAT Ligation, auxiliary-mediated ligation
Molecule size range:
Peptides up to ~200 amino acids, small proteins
Publication references:
Bertozzi Trends Biotech. 1998, Kent Science 1994, Kent JACS 1997, Danishefsky Science 2013, Bode ACIE 2006–2014
Chemical modifications:
Cys to Ala conversion, incorporation of auxiliary groups, oxaproline-mediated ligation
Solvent / conditions:
Aqueous buffers, mild conditions, low to moderate concentrations
Reaction criteria:
Chemoselectivity, covalent bond formation, stability of reactants, non-toxicity, reasonable reaction rate
Year:
2026
Region / city:
Not specified
Subject:
Neuropeptide sequences in Arma custos
Document type:
Scientific data
Institution:
Not specified
Author:
Not specified
Target audience:
Researchers in biochemistry, molecular biology, and neurobiology
Validity period:
Not specified
Approval date:
Not specified
Modification date:
Not specified