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Supplementary material presenting iron homeostasis and dopaminergic system abnormalities in Tourette syndrome, based on advanced neuroimaging techniques such as 7T MRI and PET scans, targeting subcortical nuclei and their associated iron metrics.
Year: 2023
Region / city: Leipzig, Hannover
Topic: Neuroimaging, Iron Homeostasis, Dopaminergic System, Tourette Syndrome
Document type: Research Paper
Organization / institution: Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig University, Hannover Medical School
Authors: Dimitrios G. Gkotsoulias, Michael Rullmann, Simon Schmitt, Anna Bujanow, Franziska Zientek, Konstantin Messerschmidt, André Pampel, Amira-Philine Büttner, Andreas Schildan, Osama Sabri, Kirsten Müller-Vahl, Henryk Barthel, Harald E. Möller
Target audience: Neuroscientists, Medical researchers
Period of validity: N/A
Date of approval: 2023
Date of changes: N/A
Price: 8 / 10 USD
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Referral form for assessment of ASD, ADHD, and Tourette Syndrome
Year: 2023
Region / City: United Kingdom
Topic: Health Assessment
Document Type: Referral Form
Organization: NHS
Author: NHS Professionals
Target Audience: Healthcare professionals, parents, schools
Period of validity: Not specified
Approval Date: Not specified
Date of revisions: Not specified
Referral form for assessment of ASD, ADHD, and Tourette Syndrome
Note: Year
Topic: Neurodevelopmental Disorders
Document Type: Referral Form
Target Audience: Parents, Teachers, Healthcare Professionals
Comprehensive cytogenetic analysis of suspected chromosomal abnormalities in north-western Malaysia: a 5-year study at AMDI
Year: 2006–2011
Region / city: Penang, Malaysia
Subject: Chromosomal abnormalities, cytogenetics
Document type: Research article
Institution: Advanced Medical and Dental Institute, Universiti Sains Malaysia; Institute for Medical Research, Kuala Lumpur
Authors: Mot Yee Yik, Zubaidah Zakaria, Siti Fatimah Ramli, Nazlina Isa, Ruzziatul Ema, Abdul Rahman Azhari, Abdul Razak Abdul Khalid, Narazah Mohd Yusoff
Target audience: Medical researchers, geneticists, clinicians
Sample source: Peripheral blood lymphocytes from multiple hospitals in north-western Malaysia
Methods: Karyotyping, G-banding, fluorescence in situ hybridization (FISH)
Results: 1461 cases analyzed, 1338 successful cultures, 397 cases with chromosomal abnormalities, Down syndrome most frequent, numerical abnormalities 84.38%
Comparative analysis: Compared to previous regional and international studies
Key findings: Increasing sample referrals, statistical differences in frequency of certain chromosomal abnormalities
Medical Necessity Letter for High-Resolution Chromosome Analysis in Suspected Structural Chromosome Abnormalities
Year: 2026
Region / City: [Lab Location]
Subject: Genetic Testing / Chromosome Analysis / Karyotype
Document Type: Medical Letter / Preauthorization Request
Institution: [Lab Name]
Author: [Ordering Provider / Clinician]
Patient: [Patient Name]
Insurance Company: [Insurance Company]
Test Requested: High-Resolution Chromosome Analysis (Karyotype)
CPT Codes: [CPT codes]
ICD-10 Codes: [ICD10 Codes]
Clinical Indications: Suspected ring 14/17/20, 8p inv dup del, structural chromosome abnormalities, intractable epilepsy
Pre-Test Counseling: Conducted by certified genetic counselor
Purpose: Confirm structural chromosome abnormalities undetectable by NGS, WES, WGS, or aCGH
Sample Collection: [Lab/Hospital]
Billing: [Billing Institution/Provider]
References: Thomas RH, Berkovic SF (2014); Sheidley BR, Malinowski J, Bergner AL, et al. (2022); Smith L, Malinowski J, Ceulemans S, et al. (2023); James WD, Roth R, Fitzgerald M (2024); Rinaldi B, Vaisfeld A, Amarri S, et al. (2017)
Topics: dopaminergic Tourette Abnormalities