№ files_lp_4_process_3_071652
File format: docx Character count: 26383 File size: 129 KB
Year: 2026
Region / Institution: University of Oregon, Sanford Research, Institut Curie, Necker Hospital, Hospital for Sick Children
Field: Molecular biology / Neuro-oncology
Document type: Research supplemental materials and methods
Organ / Institution: Transgenic Mouse Facility, Sanford Research, Institut Curie, Necker Hospital
Authors: Not specified
Target audience: Researchers in genetics and oncology
Experimental models: Transgenic mice, ES cells, patient-derived xenografts (PDX)
Animal procedures approval: Sanford Research IACUC, Institut Curie ethical committee IDFParis-Comité 1 (#2011-0012)
Human research approval: Institutional Review Board at Necker Hospital, Research Ethics Board at the Hospital for Sick Children
Techniques used: DNA constructs, transgenic mouse generation, orthotopic transplantation, bioluminescence imaging, NanoString gene expression profiling, DNA methylation analysis
Drugs / treatments: Tamoxifen, vismodegib
Mouse strains: C57BL/6J, B6.Cg-Tg(Atoh1-cre)1Bfri/J, Tg(Atoh1-cre/Esr1*)14Fsh/J, B6N.129-Ptch1tm1Hahn/J, C57BL/6-Tg(Neurod2-Smo*A1)199Jols/J, NOD.Cg-Prkdc Il2rg/SzJ, athymic nude, Tg(Lmx1a-cre)1Kjmi
Cell lines: JM8.N4 ES cells
Price: 8 / 10 USD
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Supplemental Figures on the Radiosensitizing Effects of WSD0628 in Brain Tumor Xenografts
Year: 2026
Region / City: Rochester, Minnesota, USA; Jinan, Shandong, China; Minneapolis, Minnesota, USA; Corona, California, USA
Subject: Oncology, Radiobiology, Pharmacology
Document Type: Supplemental Data / Research Figures and Tables
Institution: Mayo Clinic; Cheeloo College of Medicine, Shandong University; University of Minnesota; Wayshine Biopharm Inc
Authors: Zhiyi Xue, Ann C. Mladek, Sneha Rathi, Sonia Jain, Rachael A. Vaubel, Lateef A. Odukoya, Darwin A. Garcia, Lily Liu, Katrina K. Bakken, Brett L. Carlson, Lauren L. Ott, Danielle M. Burgenske, Zeng Hu, Sonja Dragojevic, Paul A. Decker, Matthew L. Kosel, William G. Breen, Shiv K. Gupta, Jeanette E. Eckel-Passow, William F. Elmquist, Wei Zhong, Jann N. Sarkaria
Target Audience: Researchers in oncology and pharmacology
Experimental Models: U251, GBM43, GBM120, GBM12, M12eGFP-fLuc2 cell lines; mouse orthotopic xenografts
Treatment Interventions: WSD0628, radiation therapy, DDR inhibitors
Assays and Measurements: TR-FRET kinase assay, Western blotting, histological evaluation, survival analysis
Statistical Methods: Two-sample t-test, median and mean ± SD reporting
Period of Study: 2026
Schematic diagram and expression analysis of AhNF-YB1 and AhNF-YB10 in transgenic Arabidopsis
Note: Year
Theme: Plant genetics, gene expression, transgenics
Document type: Research article
Target audience: Researchers in plant genetics and biotechnology
Topics: Atoh1 Xenografts transgenic