№ files_lp_4_process_3_081096
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Supplementary research material presenting a structured database search strategy used to identify studies on pharmacological treatments for Crohn disease across major biomedical literature databases.
Document type: Supplementary table
Subject: Crohn disease pharmacological treatment search strategy
Topic: Literature search methodology for inflammatory bowel disease therapies
Disease focus: Crohn disease
Interventions: Tumor necrosis factor inhibitors, monoclonal antibodies, JAK inhibitors, cytokine inhibitors, immunomodulators, aminosalicylates, methotrexate, azathioprine, mercaptopurine
Data sources: MEDLINE, Cochrane Central Register of Controlled Trials (CCTR), Embase
Search fields: Title, abstract, keywords, registry numbers
Search period: 2020–Current
Methodology: Structured database search strategy using controlled vocabulary and keyword combinations
Research context: Identification of studies on pharmacological treatments for Crohn disease
Price: 8 / 10 USD
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PROTEIN FORMULA WITH CARBOHYDRATE, FAT, VITAMINS, MINERALS AND TRANSFORMING GROWTH FACTOR BETA-2 FOR CROHN DISEASE
Year: 2023
Region / Country: Australia
Document type: Regulatory submission
Organization: Nestle Health Science
Product: Modulen® IBD
Formulation: Powder for oral liquid, 400 g
Intended use: Dietary management of Crohn disease in adults and children over 5 years
Requested quantity: 12 x 400g cans per prescription, 5 repeats
Price: AEMP $361.56, DPMQ $407.59
Place in therapy: First-line enteral nutrition for paediatric Crohn disease, alternative to corticosteroids
Clinical guidelines referenced: Gastroenterological Society of Australia (GESA) inflammatory bowel disease 2018 update
Comparator products: Peptamen Junior® for paediatric population, Fortisip® for adults
PBS listing request: Restricted Benefit
Access considerations: Rural and remote patient access, hospital-based programs
Regulatory standard: Australia New Zealand Food Standards Code — Standard 2.9.5
Supplemental Data Tables on R406 Solubility in Buffers and In Vitro Pharmacological Profile
Document type: Supplemental data tables
Subject: R406 solubility and in vitro pharmacological profiling
Compound: R406
Experimental context: Pharmacological profiling experiments
Assay types: Radioligand binding assays; isolated enzyme activity assays
Measured parameters: Solubility (µM); pIC50; pKi
Timepoints: 3 hour; 24 hour
Solvent conditions: 0.1%, 0.3%, and 1% DMSO
Buffer systems: Non-kinase buffers; kinase binding buffer; isolated kinase buffers; phosphate-buffered saline
Target scope: Non-kinase targets across enzyme, receptor, ion channel, and transporter classes
Definitions provided: Inactivity threshold defined as pIC50 of 3.5 (<50% inhibition at 10 µM or non-reproducible activity)
Supplementary Materials for a Comprehensive Review on the Chemical Properties, Plant Sources, Pharmacological Activities, Pharmacokinetic and Toxicological Characteristics of Tetrahydropalmatine
Year: 2021
Region / City: China and Southeast Asia
Subject: Pharmacology, Ethnobotany, Phytochemistry
Document Type: Supplementary material / Scientific review data
Institution: Chengdu University of Traditional Chinese Medicine
Authors: Qinyun Du, Xianli Meng, Shaohui Wang
Target Audience: Researchers and professionals in pharmacology and traditional medicine
Data Coverage: Plant species, pharmacological activities, extraction methods, and chemical properties
Date of Publication: 2021
References Included: Yes, multiple sources cited for plant species and pharmacological effects
Language: English
Document Structure: Tables with plant sources, pharmacological actions, and extraction methods
Kasni (Cichorium intybus Linn.): A Scientific Overview of Traditional and Pharmacological Uses
Year: 2026
Region / city: Global
Subject: Medicinal plants, Traditional medicine, Pharmacology
Document type: Review article
Institution / organization: Unani medicine research institutions
Author: Not specified
Target audience: Researchers, healthcare professionals, students of traditional medicine
Plant profile: Cichorium intybus Linn., including leaves, roots, flowers, and seeds
Pharmacological properties: Hypoglycemic, hypolipidemic, hepatoprotective, gastroprotective, anti-inflammatory, analgesic, antioxidant, antiallergic, antimicrobial
Traditional uses: Liver tonic, digestive aid, deobstruent, blood purifier, mild laxative
Geographical distribution: India, Europe, West Asia, South Africa
Varieties: Bustani (cultivated), Dashti (wild)
Botanical classification: Kingdom Plantae, Family Asteraceae, Genus Cichorium
Keywords: Kasni, Chicory, Coffee substitute, Unani, Therapeutic action, Traditional use
Cardiac resynchronization therapy for enabling guideline-directed pharmacological therapy optimization in heart failure
Year: 2008-2021
Region: Sweden
Topic: Heart failure management and cardiac resynchronization therapy
Document type: Supplemental material / Research tables
Organization: European Society of Cardiology, SwedeHF, NPR, NPDR
Authors: Not specified
Target audience: Cardiologists, researchers, clinicians in cardiology
Data sources: SwedeHF, National Patient Register (NPR), National Prescribed Drug Registry (NPDR), ICD & PM Registry, LISA, RTP
Variables: Demographics, clinical parameters, comorbidities, treatment, socioeconomics
Methodology: Data extraction from registries, calculation of target doses, follow-up analysis
Limitations: Missing data in some variables, assumptions for combination drug dosing
Guideline period: 2008-2021 ESC HF guidelines
Postdoctoral Fellowship Competition in Chemical, Pharmacological, and Bioengineering Fields
Year: 2017
Region / City: New Jersey
Topic: Postdoctoral Fellowship
Document Type: Announcement
Organization: New Jersey Institute of Technology
Author: Not specified
Target Audience: Young scientists with a PhD
Effective Period: N/A
Approval Date: N/A
Amendment Date: N/A
Topics: 2020–Current CROHN Pharmacological