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The article presents a research study on how bone marrow mesenchymal stem cell (BMSC) therapy can regulate gut microbiota to improve neurological recovery after ischemic stroke in rats.
Year:
2021
Region / city:
Tianjin, China
Subject:
Stem Cell Therapy, Neurological Function, Ischemic Stroke, Gut Microbiota
Document type:
Research Article
Organization / Institution:
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin Key Laboratory of Translational Research of TCM Prescription and Syndrome
Author:
Zhao LN, Ma SW, Xiao J, Yang LJ, Xu SX, Zhao L
Target audience:
Researchers, Healthcare professionals, Medical practitioners
Period of validity:
Not specified
Approval date:
December 11, 2021
Date of revisions:
July 6, 2021
Publication date:
December 26, 2021
Price: 8 / 10 USD
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Year:
Not specified
Region / city:
China
Study type:
Longitudinal observational study
Population:
Stroke patients
Sample size:
T1=339, T2=310, T3=279
Variables measured:
Age, gender, marital status, residence status, educational level, place of residence, religious beliefs, medical payment method, number of children, monthly household income, occupation, stroke type, number of strokes, family history of stroke, stroke site, NIHSS score, BMI, course of stroke, number of comorbidities, PSF, resilience
Time points:
T1 (acute hospitalization), T2 (three months after discharge), T3 (six months after discharge)
Currency:
RMB (Chinese yuan)
Year:
2024
Region / City:
Australia
Topic:
Orthoptics, Post-Stroke Vision Care
Document Type:
Research Survey
Organization:
La Trobe University
Author:
Associate Professor Connie Koklanis, Associate Professor Meri Vukicevic, Marc Eng
Target Audience:
Orthoptists working with stroke patients in Australia
Period of Action:
N/A
Approval Date:
N/A
Date of Changes:
N/A
Year:
2019
Region / City:
N/A
Topic:
Climate Change, Ecosystem Restoration
Document Type:
Article
Author:
John Feldman
Target Audience:
General Public, Environmentalists
Period of Action:
N/A
Approval Date:
N/A
Date of Changes:
N/A
Note:
Context
Authors:
Cassandra M. Juran; Justina Zvirblyte; Yasaman Sharazi; Angela Kubik; Margareth Cheng-Campbell; Elizabeth Blaber; Eduardo Almeida
Affiliations:
Blue Marble Space Institute of Science at NASA Ames Research Center, Mountain View, CA, USA; Vilnius University, Vilnius, Lithuania; Rensselaer Polytechnic Institute, Troy, NY, USA; NASA Ames Research Center, Moffett Field, CA, USA
Research Field:
Stem cell biology; Bone regeneration; Mechanobiology; Space biology
Key Gene:
CDKN1A (Cdkn1a)
Experimental Models:
Wildtype and Cdkn1a-null mice
Methods:
Single-cell mRNA sequencing; in-vitro mechanical stretch; hindlimb unloading; running wheel and treadmill loading; spaceflight microgravity exposure
Space Mission:
Rodent Research-10 aboard the International Space Station
Duration of Spaceflight:
30 days
Biological Material:
Femur bone marrow; mesenchymal osteoprogenitors; osteoblast lineage cells
Type of Document:
Scientific research article
Institutional Context:
NASA-affiliated and academic biomedical research collaboration
Authors:
Junqing Li; Zhihua Wang; Juan Wang; Qian Guo; Yi Fu; Zihan Dai; Minghao Wang; Yu Bai; Xin Liu; Paul Cooper; Jiayuan Wu; Wenxi He
Academic Field:
Dentistry; Stem Cell Biology; Molecular Signaling
Research Topic:
Regulation of dental pulp stem cell differentiation by amphiregulin
Document Type:
Supplementary figures and experimental data
Content Type:
Full-length gels and western blot images of protein expression
Biological Markers:
Odontoblastic markers
Signaling Pathways:
Mitogen-activated protein kinase (MAPK); Phosphatidylinositol 3-kinase (PI3K)
Figures Referenced:
Figure 3; Figure 5; Figure 6
Supplementary Materials:
Supplementary Figure 1; Supplementary Figure 2
Experimental Method:
Protein expression analysis using gel and blot imaging
Institutional Affiliation:
Not specified in the provided text
Publication Context:
Supplementary material accompanying a scientific research article
Year:
2026
Region / City:
Shanghai, China; Neijiang, Sichuan, China; Adelaide, Australia
Topic:
Aquaculture, Lipid Metabolism, Myo-inositol
Document Type:
Research Article
Institution:
East China Normal University, Neijiang Normal University, Flinders University
Authors:
Xianyong Bu, Xiaodan Wang, Zhideng Lin, Chunling Wang, Lingyu Li, Shubin Liu, Qingchao Shi, Jian G. Qin, Liqiao Chen
Target Audience:
Researchers, Aquaculture Professionals, Environmental Health Specialists
Period of Study:
56 days
Date of Approval:
Not specified
Date of Modifications:
Not specified
Context:
This scientific article presents research on the effects of myo-inositol supplementation on the growth, antioxidant status, and lipid metabolism of Chinese mitten crabs in aquaculture.
Year:
2021
Region / city:
Haikou, Hainan, China
Topic:
Cancer research, Molecular biology
Document type:
Research article
Institution:
Hainan University, Central South University
Authors:
Yingai Zhang, Yuting Zhang, Shuai Zhou, Mujeeb Ur Rehman, Fankai Lin, Jianquan Zhang, Hailong Zhou
Target audience:
Researchers, Medical professionals, Oncology specialists
Period of validity:
Ongoing
Approval date:
Not provided
Modification date:
Not provided
Year:
Not specified
Region / City:
Not specified
Topic:
Hematopoietic progenitor cell (HPC) donor screening
Document Type:
User instructions / Guidelines
Organization / Institution:
Interorganizational Uniform Donor History – HPC Task Force
Author:
Not specified
Target Audience:
Healthcare providers involved in donor screening
Validity Period:
Not specified
Approval Date:
Not specified
Date of Amendments:
Not specified
Year:
May 2018
Region / city:
United States
Topic:
Donor Screening, Medical History
Document Type:
Questionnaire
Author:
Not specified
Target Audience:
Potential organ and tissue donors
Duration:
Ongoing, no specific expiration date mentioned
Approval Date:
May 2018
Date of Changes:
Not mentioned
Additional Notes:
Includes questions on Zika virus, HIV, hepatitis, malaria, and other conditions
Context:
A medical questionnaire used to assess the eligibility of individuals for donating human cells, tissues, and related products.
Year:
Not specified
Region / City:
Not specified
Topic:
Haematopoietic Stem Cell Transplantation Nursing
Document Type:
Terms of Reference
Organization:
European Society for Blood and Marrow Transplantation (EBMT)
Author:
Not specified
Target Audience:
Nurses and healthcare professionals involved in HSCT
Period of Validity:
Not specified
Approval Date:
Not specified
Date of Changes:
Not specified
Note:
Year
Authors:
Cassandra M. Juran; Justina Zvirblyte; Yasaman Sharazi; Angela Kubik; Margareth Cheng-Campbell; Elizabeth Blaber; Eduardo Almeida
Affiliations:
Blue Marble Space Institute of Science at NASA Ames Research Center, Mountain View, CA, USA; Vilnius University, Vilnius, Lithuania; Rensselaer Polytechnic Institute, Troy, NY, USA; NASA Ames Research Center, Moffett Field, CA, USA
Research Field:
Stem cell biology; Bone regeneration; Mechanobiology; Space biology
Key Gene:
CDKN1A (Cdkn1a)
Experimental Models:
Wildtype and Cdkn1a-null mice
Methods:
Single-cell mRNA sequencing; in-vitro mechanical stretch; hindlimb unloading; running wheel and treadmill loading; spaceflight microgravity exposure
Space Mission:
Rodent Research-10 aboard the International Space Station
Duration of Spaceflight:
30 days
Biological Material:
Femur bone marrow; mesenchymal osteoprogenitors; osteoblast lineage cells
Type of Document:
Scientific research article
Institutional Context:
NASA-affiliated and academic biomedical research collaboration
Year:
2026
Region / Institution:
Not specified
Topic:
Immunology, SARS-CoV-2, Vaccine Response
Document type:
Peer Review
Author:
Stefania P Bjarnarson
Target audience:
Researchers, Immunologists
Study period:
Up to 33 months post mRNA vaccination
Methods:
Analysis of bone marrow plasma cells, healthy adult donors, post-vaccination sampling
Key findings:
Limited presence of SARS-CoV-2-specific long-lived plasma cells in bone marrow after mRNA vaccination or hybrid immunity
Data source:
Bone marrow aspirates, hip joint replacement surgery samples
Limitations:
Small sample size, discrepancies in patient description, consideration of asymptomatic infections
Scientific relevance:
Provides evidence on the longevity of humoral immune response post-vaccination
Concise description:
Peer-reviewed evaluation of a study assessing the presence of SARS-CoV-2-specific long-lived plasma cells in the bone marrow following mRNA vaccination and hybrid immunity, highlighting methodology, key results, and points for revision.
Year:
2023
Region / City:
National
Topic:
Bone Marrow Failure Syndromes
Document Type:
Abstract
Author:
Smith, John A1; Doe, Jane B2
Target Audience:
Medical professionals, researchers
Period of validity:
N/A
Approval Date:
N/A
Date of changes:
N/A
Authors:
Charles W. Chesnutt; Frank Norris; Henry James
Years of publication:
1901–1902
Literary genre:
Novel; literary fiction
Form:
Prose excerpts
Language:
English
Geographical context:
United States; England
Main characters mentioned:
Major Carteret; Olivia Carteret; Dr. Price; Presley; Hooven; Kate Croy
Themes:
illness and family anxiety; rural life and agriculture; social environment and personal relations
Historical period depicted:
Late 19th – early 20th century
Type of document:
Literary source; excerpts from published novels