№ files_lp_4_process_3_087946
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Supplementary material reporting the characteristics of adult participants and the distribution of metals in toenail samples measured by ICP-MS, including data transformations and sub-sample comparisons.
Year:
2026
Region / City:
Baltimore, MD, USA; Research Triangle Park, NC, USA; Durham, NC, USA; Chapel Hill, NC, USA
Subject:
Environmental health; Biomonitoring; Heavy metals
Document Type:
Supplementary material
Institution:
Johns Hopkins Bloomberg School of Public Health; National Institute of Environmental Health Sciences; Social & Scientific Systems, Inc.; University of North Carolina Gillings School of Global Public Health
Authors:
Joyce J.Y. Lin, Lily J. Koffman, Mina W. Tehrani, Rui Chen, Dale P. Sandler, Kaitlyn G. Lawrence, W. Braxton Jackson II, Aisha S. Dickerson, Gurumurthy Ramachandran, Lawrence S. Engel, Ana M. Rule
Study Population:
Adult participants aged 20–69, racially diverse
Data Collection Period:
Not specified
Analytical Methods:
ICP-MS gas modes for elemental analysis, log10 transformation, Shapiro-Wilk test for normality
Measured Elements:
Al, Cd, Cu, Fe, Mg, Mn, Pb, Sb, V, Zn, As, Ca, Cr, Ni, Se, Co, Hg, Mo
Sample Type:
Toenail clippings
Figures and Tables:
Distributions of metal concentrations, sub-sample agreement scatterplots, density plots comparing elemental concentrations
Price: 8 / 10 USD
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The product description is provided for reference. Actual content and formatting may differ slightly.
Year:
2021
Region / City:
Pirassununga, SP, Brazil
Topic:
Veterinary medicine, animal welfare, swine castration
Document Type:
Research article
Institution:
University of Sao Paulo, North Carolina State University, Washington State University, Michigan State University, Iowa State University, University of Missouri
Author:
Laya Kannan Silva Alves, Monique Danielle Pairis-Garcia, Juliana Bonin Ferreira, Victoria Rocha Merenda, Rubia Mitalli Tomacheski, Pedro Henrique Esteves Trindade, Christopher Siepker, Magdiel Lopez-Soriano
Target Audience:
Researchers, veterinary professionals
Period of Study:
Not specified
Approval Date:
Not specified
Date of Revision:
Not specified
Year:
2025
Region / city:
Victoria
Subject:
Cancer biomarkers
Document type:
Regulatory document
Organization / institution:
Department of Health
Author:
Unknown
Target audience:
Healthcare professionals, pathology laboratories
Effective date:
18 September 2025
Date of approval:
Unknown
Date of amendments:
Unknown
Year:
2023
Program:
Lysosomal Biomarkers Program
Document Type:
Pre-Proposal Template
Intended Audience:
Principal Investigators and Research Teams
Submission Format:
PDF
Institution/Company:
[To be filled by applicant]
Principal Investigator:
[To be filled by applicant]
Project Focus:
Biomarker development, characterization, or validation
Target Disease:
Parkinson’s Disease
Scope:
Experimental plan including rationale, study design, and resource availability
Inclusion Considerations:
Diversity, equity, and inclusion in sample selection
Authors:
Joshua B. Ewen; Claudio Babiloni; Gary S. Collins; Lauren E. Ethridge; Jean Gotman; Akio Ikeda; Philippa J. Karoly; William Z. Potter; Stephan Rampp; Margitta Seeck; Sándor Beniczky
Submitting body:
IFCN Executive Committee
Submission date:
15 July 2024
Organ / Institution:
International Federation of Clinical Neurophysiology (IFCN)
Document type:
Reporting guideline; Explanation and Elaboration document
Field:
Clinical neurophysiology; EEG-based biomarkers
Scope:
Evaluation and reporting of clinical biomarker accuracy studies involving EEG technologies
Related frameworks:
STARD; TRIPOD; EQUATOR Network
Intended use:
Reporting standards across biomarker validation phases (Phase 1–3)
Contexts of Use:
Diagnostic; Monitoring; Response; Predictive; Prognostic; Safety; Susceptibility/Risk
Validation phases described:
Phase 1 (Discovery); Phase 2 (Preliminary validation); Phase 3 (Validation)
Year:
2019
Region / City:
Boston, MA, USA
Topic:
Biomarkers, therapeutic development, clinical trials
Document type:
Article
Organization / Institution:
Harvard Business School, Harvard-MIT Center for Regulatory Science
Author:
Ariel Dora Stern
Target Audience:
Researchers, regulators, the therapeutics industry
Period of validity:
N/A
Approval Date:
May 22, 2019
Funding:
Kauffman Foundation
Running title:
Biomarker ratios for personalized therapeutic decisions
Authors:
Dejana Bajić; Nemanja Todorović; Mladena Lalić Popović; Ljiljana Andrijević
Affiliation:
Department of Biochemistry, Faculty of Medicine, University of Novi Sad; Department of Pharmacy, Faculty of Medicine, University of Novi Sad
Institution:
Institute for Pulmonary Diseases of Vojvodina, Clinic for Intensive Medicine and Vascular Pulmonary Diseases, Department for Intensive Care and Intoxications Level 3
Country:
Serbia
Corresponding author:
Dejana Bajić, MD, PhD
ORCID IDs:
0000-0002-7958-068X; 0000-0002-1519-5643; 0000-0001-8354-3868; 0000-003-0676-7985
Study design:
Retrospective observational clinical study
Study period:
November 2020 – February 2022
Sample size:
133 ICU patients with COVID-19-related sepsis
Primary endpoint:
28-day mortality
Biomarkers analyzed:
Neutrophil-to-lymphocyte ratio (NLR); Fibrinogen-to-albumin ratio (FAR); C-reactive protein-to-albumin ratio (CAR)
Statistical methods:
ROC curve analysis; logistic regression
Ethical approval:
Ethics Committee of the Institute for Pulmonary Diseases of Vojvodina (Protocol Code No. 9-II/3, February 24, 2022); Ethics Committee of the Faculty of Medicine, University of Novi Sad (Protocol Code No. 01-39/190/1)
Conflicts of interest:
None declared
Funding:
No financial support received
Keywords:
biomarkers; COVID-19; inflammation; prognosis
Year:
2026
Region / City:
Ulm, Germany
Theme:
Blood biomarkers, Frailty, Geriatrics
Document Type:
Research Study
Institution:
Ulm University Medical Centre
Author:
Felix Boehm MSc, Lea Fritzenschaft, MD, Stefanie Braig, Michael Denkinger, MD, Dietrich Rothenbacher, MD, Dhayana Dallmeier, MD
Target Audience:
Researchers, Healthcare professionals, Geriatric specialists
Period of Validity:
Not specified
Approval Date:
Not specified
Modification Date:
Not specified
Year:
2026
Region / City:
Beijing
Topic:
Biomarkers, Environmental Science
Document Type:
Research Supplement
Institution:
Peking University
Authors:
Fanrong Zhao, Qiyue Kang, Xiaohua Zhang, Jiaying Liu, Jianying Hu
Target Audience:
Researchers in environmental sciences, toxicology
Period of Validity:
N/A
Approval Date:
N/A
Date of Last Update:
N/A
Contextual Description:
Research supplement detailing the synthesis and analysis of biomarkers for human exposure to flame retardants.
Year:
2023
Region / City:
Europe
Field:
Biomarkers, Clinical Research
Document Type:
Guidelines
Organization:
BioMS-eu
Author:
Michael Khalil
Target Audience:
Researchers, Clinical Laboratories
Period of Validity:
Not specified
Approval Date:
Not specified
Date of Modifications:
Not specified
Context:
This document outlines the procedures and requirements for collaboration in research studies related to biomarkers within the BIOMS-eu network.
Year:
2024
Region / City:
New Zealand
Topic:
Medical research, concussion biomarkers
Document Type:
Consent form
Institution:
Health and Disability Ethics Committee, New Zealand
Principal Investigator:
Professor Patria Hume
Co-Investigators:
Dr Ed Maunder, Professor Alice Theadom, Dr Beth McQuiston, Dr Chris Puliu’vea, Dr Doug King, Dr Stephen Kara, Assoc Prof Mangor Pedersen, Dr Liza Kunz, et al.
Target Audience:
Female research participants
Study Period:
November 2024 – March 2025
Ethics Approval Date:
March 2025
Ethics Reference Number:
HDEC 2024 EXP 21888
Trial Registry:
ANZCTR ACTRN12625000260426
Consent Type:
Informed voluntary participation with options for data use and future contact
Year:
2024
Field:
Oncology, Precision Medicine
Document type:
Review article
Authors:
Bore et al.
Keywords:
ctDNA, CTCs, Extracellular vesicles, Liquid biopsy, Tumour-educated platelets, Precision oncology
Intended audience:
Medical researchers, clinicians
Biological materials analyzed:
Blood, urine, saliva, cerebrospinal fluid, semen
Technologies discussed:
Next-generation sequencing, digital PCR, microfluidic CTC capture
Clinical applications:
Cancer diagnosis, prognosis, treatment monitoring, detection of therapy resistance
Research trends:
Peak in scientific publications in 2024
Year:
2020
Region / City:
California
Subject:
Reliability requirements for resource adequacy and capacity procurement
Document Type:
Business Practice Manual
Organization / Institution:
California ISO
Author:
Dede Subakti
Target Audience:
Load-serving entities, capacity procurement participants
Period of validity:
From 05/01/18
Approval Date:
03/27/09
Date of last revision:
10/05/2020
Year:
2023
Region / city:
United States
Topic:
Extreme Cold Weather Preparedness
Document type:
Audit worksheet
Organization:
North American Electric Reliability Corporation (NERC)
Author:
Compliance Enforcement Authority (CEA)
Target audience:
Registered entities subject to NERC standards
Period of validity:
Ongoing
Approval date:
N/A
Date of modifications:
N/A
Note:
Audit ID
Note:
Audit ID
Text with blue background:
Fixed text – do not edit
Text entry area with Green background:
Entity-supplied information
Text entry area with white background:
Auditor-supplied information
Compliance Narrative (Required):
Provide a brief explanation, in your own words, of how you comply with this Requirement. References to supplied evidence, including links to the appropriate page, are recommended.
Evidence Requested:
Provide the following evidence, or other evidence to demonstrate compliance.
Registered Entity Evidence (Required):
The following information is requested for each document submitted as evidence. Also, evidence submitted should be highlighted and bookmarked, as appropriate, to identify the exact location where evidence of compliance may be found.
Note to Auditor:
Auditors are advised to monitor compliance with Requirement R1 during events, due to the importance of issuing Operating Instructions in such instances. Auditors can obtain a population of events for sampling from NERC’s, or the Regional Entity’s, records of mandatory event reports, other information available at the Regional Entities, or a query of the entity. Auditors are encouraged to monitor compliance during the most critical events on the entity’s system occurring during the compliance monitoring period.
Registered Entity Response (Required):
Question: Did the entity receive an Operating Instruction from the Reliability Coordinator during the audit period?
If No, state how this was ascertained. If yes, provide a list of instances of receiving Operating Instructions from the Reliability Coordinator. [Note:
A separate spreadsheet or other document may be used. If so, provide the document reference below.]
Year:
2006
Region / City:
United States
Topic:
Reliability Standards, Compliance
Document Type:
Audit Worksheet
Organization / Institution:
NERC
Author:
NERC
Target Audience:
Registered Entities, Compliance Enforcement Authority
Effective Period:
From 6/18/2007
Approval Date:
11/1/2006
Amendment Date:
3/16/2007
Note:
Audit ID
Regions covered:
North America, NERC compliance
Type of Document:
Compliance Audit Worksheet
Year:
2022
Region / City:
Northeastern North America
Topic:
Distributed Energy Resources (DER), Bulk Power System (BPS), Reliability, System Resilience, Electrification
Document Type:
Guidance Document
Organization / Institution:
NPCC
Author:
NPCC Regional Standards Committee
Target Audience:
NPCC Members, Stakeholders, Engineers, Policy Makers
Effective Period:
2022 and ongoing
Approval Date:
May 11, 2022
Revision Date:
2022 (Appendix J development)
Registered Entity:
Registered name of entity being audited
NCR Number:
NCRnnnnn
Compliance Enforcement Authority:
Region or NERC performing audit
Compliance Assessment Date(s):
Month DD, YYYY, to Month DD, YYYY
Compliance Monitoring Method:
[On-site Audit | Off-site Audit | Spot Check]
Names of Auditors:
Supplied by CEA
Applicability of Requirements:
BA, DP, GO, GOP, PA/PC, RC, RP, RSG, TO, TOP, TP, TSP
Requirements Covered:
D.B.1, D.B.2, D.B.3, D.B.4, R6, R7, R8, R9, R10, D.B.11, D.B.12
UFLS Entities Definition:
Distribution Providers, UFLS-Only Distribution Providers, Transmission Owners, and Transmission Owners that own Elements identified in the UFLS program
Supporting Evidence:
Compliance narratives, reports, memorandums, emails, and other documentation demonstrating compliance with PRC-006-5 requirements
Subject Matter Experts:
SME Name, Title, Organization, Requirement(s)
Compliance Assessment Approach:
Verification of joint regional review participation, island identification, and UFLS program adoption within Western Interconnection
Time Horizon:
Long-term Planning
VRF Level:
Medium
Year:
2020
Region / city:
Not specified
Topic:
Safety and reliability in power export curtailment
Document type:
Workshop topics and discussion points
Organization:
Not specified
Author:
Not specified
Target audience:
Utility companies, grid operators, energy regulators
Period of validity:
Not specified
Approval date:
Not specified
Amendment date:
Not specified