№ files_lp_4_process_2_49135
File format: docx
Character count: 6909
File size: 26 KB
Detailed experimental analysis of ICOS expression and T cell functionality across various tumour models, including cross-reactivity, internalization assays, and survival data from different animal models.
Year:
2023
Region / city:
N/A
Topic:
Immune cell characterization, ICOS expression, tumour immunology
Document type:
Research figure legends
Organization / institution:
N/A
Author:
N/A
Target audience:
Researchers in immunology and oncology
Duration of action:
N/A
Approval date:
N/A
Date of changes:
N/A
Price: 8 / 10 USD
The file will be delivered to the email address provided at checkout within 12 hours.
The file will be delivered to the email address provided at checkout within 12 hours.
Don’t have cryptocurrency yet?
You can still complete your purchase in a few minutes:- Buy Crypto in a trusted app (Coinbase, Kraken, Cash App or any similar service).
- In the app, tap Send.
- Select network, paste our wallet address.
- Send the exact amount shown above.
The final amount may vary slightly depending on the payment method.
The file will be sent to the email address provided at checkout within 24 hours.
The product description is provided for reference. Actual content and formatting may differ slightly.
Document type:
Supplementary material
Scientific field:
Molecular biology
Research focus:
Anticalin selection and affinity maturation
Target protein:
Membrane-bound Hsp70
Methodology:
Bacterial surface display
Techniques:
FACS screening, affinity maturation, directed evolution, SPR, CD spectroscopy, flow cytometry
Biological models:
E. coli, FaDu cells, OPM-2 cells
Authors:
Lars Friedrich; Petra Kornberger; Claudia T. Mendler; Gabriele Multhoff; Markus Schwaiger; Arne Skerra
Figures included:
Figures S1–S7
Related publication:
Main research article on Anticalin selection against Hsp70
Experimental scope:
In vitro binding analysis and cellular characterization
Note:
Year
Note:
Year
Note:
Year
Subject:
Medical referral
Document type:
Referral form
Organization / Institution:
The Royal Orthopaedic Hospital
Target audience:
Healthcare professionals, medical specialists
Contextual description:
Form for referring patients to the Bone Tumour Service at The Royal Orthopaedic Hospital, including details about patient history, diagnosis, and referral process.
Year:
2023
Region / City:
London, Norwich, Liverpool, UK
Topic:
Medical Research
Document Type:
Systematic Review with Meta-Analysis
Author:
Tristan D Boam, Melissa Gabriel, Rajeev Shukla, Paul D Losty
Target Audience:
Healthcare professionals, researchers in paediatric oncology
Period of Effect:
1990-2020
Approval Date:
Not specified
Date of Changes:
Not specified
Year:
2022
Region / city:
Birmingham, UK
Topic:
Medical Referral
Document type:
Referral Form
Organization:
Royal Orthopaedic Hospital
Author:
Not specified
Target audience:
Healthcare professionals, referring consultants
Effective period:
Not specified
Approval date:
Not specified
Amendment date:
Not specified
Year:
2023
Region / city:
Not specified
Topic:
Cancer research, muscle index, and treatment effects
Document type:
Research table
Organization / institution:
Not specified
Author:
Not specified
Target audience:
Researchers, medical professionals
Period of validity:
Not applicable
Approval date:
Not specified
Date of changes:
Not specified
Year:
2023
Region / City:
Manchester
Subject:
Genomic testing for cancer types
Document Type:
Medical Form
Organization:
North West Genomic Laboratory Hub
Author:
North West Genomic Laboratory Hub
Target Audience:
Medical professionals, Pathologists
Validity Period:
Not specified
Approval Date:
Not specified
Modification Date:
Not specified
Year:
2021
Organisation:
International Collaboration on Cancer Reporting
Document type:
Histopathology reporting guide
Subject:
Gastrointestinal stromal tumour (GIST)
Scope:
Pathology reporting of resection specimens for GIST
Exclusions:
Metastatic GIST specimens
Edition:
1st edition
Applicable staging system:
Pathological TNM staging
Evidence framework:
NHMRC levels of evidence
Intended users:
Pathologists reporting GIST resection specimens
Related publications:
Gastrointestinal Stromal Tumour (GIST) Histopathology Reporting Guide – Biopsy Specimens; Soft Tissue Sarcoma Histopathology Reporting Guide – Resection Specimens
Year:
2023
Region / City:
United Kingdom
Topic:
Genomic Testing, Tumour Referral
Document Type:
Referral Form
Organization / Institution:
NW Genomic Laboratory Hub
Author:
Not specified
Target Audience:
Clinicians, Medical Professionals
Period of Validity:
Not specified
Approval Date:
Not specified
Date of Changes:
Not specified
Year:
2023
Region / Institution:
Multiple international research centers including 4HF Biotec GmbH, Oncotest GmbH, Charles River Discovery Research Services Germany GmbH
Subject Area:
Oncology, Pharmacology, Molecular Biology
Document Type:
Supplementary Material / Research Data
Experimental Models:
Patient-derived xenografts (PDX), Cell line-derived xenografts (CDX), Cell lines, Mouse tumour models
Methods:
RNA expression analysis (TPM), Affymetrix GeneChip arrays, SNP6.0 arrays, Whole-exome sequencing, Mass cytometry, Radiomics-based CT scans
Drug:
Rogenolisib (IOA-244)
Patient Cohorts:
Solid tumour patients, mUM, mCM, NHL-FL, mesothelioma
Endpoints:
Burden of therapy, Treatment-emergent adverse events (TEAEs), CD63+ basophils, Tumour lesion changes, Cell-free DNA, Protein expression levels, Immunoglobulin levels
Analyses:
Kaplan–Meier survival analysis, ANOVA, Linear mixed effect models, Correlation analyses
Timepoints:
Baseline to Week 16, up to Cycle 5 for patient-reported outcomes
Genetic Data:
SNVs, insertions/deletions, TMB, selected gene variants
Year:
2026
Region / City:
Multicenter, Europe
Subject:
Nuclear medicine dosimetry for neuroendocrine tumors
Document type:
Supplementary material / Research methods
Institution:
Siemens A.G., Symbia T6 imaging centers
Author:
Clinical imaging research team
Target audience:
Medical physicists, nuclear medicine specialists
Study period:
4-, 24-, and 72-hours post-injection imaging
Radiopharmaceutical:
177Lu-DOTA-octreotate
Analytical methods:
SPECT/CT quantitation with attenuation, dead-time, and scatter correction, three-phase exponential time-activity curve fitting
Outcome:
Tumour dose factors and population standard deviation
Year:
2026
Research Area:
Immunology, Cancer Biology
Document Type:
Scientific Article Supplementary Data
Authors:
Guoying Ni et al.
Organ / Institution:
Not specified
Experimental Model:
TC-1 tumour-bearing mice
Treatments:
Caerin 1.1/1.9 peptides, P3, PD-1 blockade
Cell Types Studied:
Macrophages, B cells, NK cells, Dendritic cells, T cells
Methods:
Single-cell RNA sequencing, GO and KEGG enrichment analysis
Key Findings:
Modulation of immune cell populations and activation pathways in tumour microenvironment
Supplementary Figures:
13A-F, 14A-F
Year:
2018
Region / Institution:
University of British Columbia
Subject:
Laboratory animal welfare and tumour monitoring
Document type:
Protocol / Guidelines
Responsible organization:
Animal Care and Ethics Committee
Authors:
Ullman-Culleré M.H., Foltz C.J., et al.
Target audience:
Laboratory animal researchers and veterinarians
Monitoring period:
Daily post-procedure observations
Date of publication:
2018
References:
https://animalcare.ubc.ca/sites/default/files/documents/Tumour%20Ulceration%20Guideline%202018%20final.pdf, Olfert et al. 1998, Jensen et al. 2008, Morton 2000
Year:
2026
Region / city:
Not specified
Topic:
Genome and Transcriptome Sequencing
Document Type:
Research paper
Institution:
Not specified
Author:
Not specified
Target audience:
Researchers, bioinformaticians
Validity period:
Not specified
Approval date:
Not specified
Modification date:
Not specified
Year:
Not specified
Region / City:
Not specified
Subject:
Data sync, Project document upload
Document Type:
Instruction manual
Organization / Institution:
Not specified
Author:
Not specified
Target Audience:
Not specified
Period of validity:
Not specified
Approval Date:
Not specified
Date of Changes:
Not specified
APAR:
OA64283
Product:
z/OS DFSMSrmm
Document type:
APAR documentation change record
Affected publications:
z/OS DFSMSrmm Implementation and Customization Guide; z/OS DFSMSrmm Application Programming Interface; z/OS MVS System Messages Vol 5 (EDG-GLZ); z/OS DFSMSrmm Managing and Using Removable Media
Change scope:
Introduction of HSKP housekeeping functionality switch
Components affected:
EDGRMMxx parmlib member; OPTION command; EDGHSKP utility
Change numbers:
1–15
Order number:
SC23-6874-50
Subject area:
Inventory management and housekeeping processing
Source type:
IBM system documentation update describing APAR-driven changes to multiple z/OS DFSMSrmm manuals with detailed modifications to parameters, syntax diagrams, and operational behavior related to the HSKP housekeeping functionality switch.
Year:
2020
Region / City:
Addis Ababa, Ethiopia
Theme:
Consultancy Services, SAP Travel Management
Document Type:
Request for Expression of Interest
Organization / Institution:
African Union Commission
Author:
African Union Commission
Target Audience:
Consultants from African Union Member States
Period of Action:
Not specified
Approval Date:
21st July 2020
Modification Date:
Not specified
Year:
2002
Region / City:
South Africa
Topic:
Disaster Management
Document Type:
Legislation and Guidelines
Authority:
Municipal Disaster Management Centres
Author:
Not specified
Target Audience:
Municipal Disaster Management Centres
Period of Validity:
Ongoing
Approval Date:
Not specified
Date of Revisions:
Not specified
Year:
2024
Region / City:
Spokane Valley
Topic:
GIS Mapping and Spatial Analysis
Document Type:
User Guide
Organization:
Spokane Valley
Audience:
General public, GIS users
Period of Validity:
Ongoing
Approval Date:
2024
Modification Date:
N/A