№ files_lp_4_process_3_107052
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Structured MEDLINE database search strategy listing controlled vocabulary and keyword combinations used to retrieve randomized clinical studies on rehabilitation and exercise interventions for chronic obstructive pulmonary disease.
Database:
MEDLINE
Subject area:
Pulmonary medicine and rehabilitation
Research topic:
Chronic obstructive pulmonary disease and rehabilitation interventions
Document type:
Literature search strategy
Methodology:
Randomized controlled trials and controlled clinical trials
Health condition:
Chronic obstructive pulmonary disease (COPD) and pulmonary emphysema
Intervention types:
Rehabilitation, physiotherapy, physical therapy, exercise training, breathing exercises
Search components:
Disease terms, rehabilitation and exercise terms, randomized trial filters
Search structure:
Boolean logic combining disease, intervention, and trial methodology terms
Population scope:
Human subjects
Purpose:
Identification of clinical trials on rehabilitation and exercise interventions in COPD
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Year:
2015
Region / city:
Not specified
Topic:
Medical research, Ultrasound in shock diagnosis
Document type:
Research study
Institution:
Not specified
Author:
Ghane MR, Gharib MH, Ebrahimi A, et al.
Target audience:
Medical professionals, researchers
Effective period:
Not specified
Approval date:
Not specified
Date of changes:
Not specified
Year:
2014
Region / City:
Global
Topic:
Medical Research, Back Pain, Guidelines
Document Type:
Research Strategy
Organization:
Not specified
Author:
Not specified
Target Audience:
Healthcare professionals, researchers
Validity Period:
Not specified
Approval Date:
Not specified
Modification Date:
Not specified
Year:
N/A
Region / City:
Sub-Saharan Africa
Subject:
Health workers, contraceptives, knowledge, attitudes, practices
Document Type:
Search strategy
Organization / Institution:
N/A
Author:
N/A
Target Audience:
Researchers, healthcare professionals
Period of Validity:
N/A
Date of Approval:
N/A
Date of Changes:
N/A
Document Type:
Supplementary table
Database:
Ovid MEDLINE
Subject:
Cutaneous Lupus Erythematosus and plant-derived or antimalarial interventions
Content Type:
Search strategy
Medical Subject Headings (MeSH):
Lupus Erythematosus, Cutaneous; Plants; Plant Structures; Fungi; Bacteria; Herbal Medicine; Antimalarials; Artemisinins; Chloroquine; Quinidine; Quinine
Keywords Included:
botanical terms, herbal medicine, traditional Chinese medicine, Janus kinase inhibitors, antimalarial agents, specific plant genera and compounds
Search Fields:
Title and abstract (ti,ab)
Boolean Logic:
Combination of controlled vocabulary and keyword terms using AND/OR operators
Purpose:
Identification of relevant biomedical literature
Year:
2026
Source database:
Medline
Subject:
Mental health disorders and patient adherence to treatment
Document type:
Search strategy / systematic review protocol
Disorders covered:
Mood disorders, depressive disorders, anxiety disorders, somatoform disorders, adjustment disorders, neurotic disorders
Interventions included:
Psychotherapy, cognitive behavioral therapy, mind-body therapies, art and expressive therapies, counseling, psychoeducation, pharmacological adherence
Study designs included:
Randomized controlled trials, controlled clinical trials, double-blind and single-blind studies, pragmatic trials
Keywords:
adherence, compliance, treatment participation, therapy, patient engagement
Target population:
Patients with mental health disorders
Search date:
2026
Database coverage:
MEDLINE
Year:
Not specified
Region / City:
Not specified
Subject:
Medical Research, Myocardial Infarction, Cardiovascular Disease
Document Type:
Research Analysis
Organization / Institution:
Not specified
Author:
Not specified
Target Audience:
Medical Professionals, Researchers
Period of Action:
Not specified
Approval Date:
Not specified
Amendment Date:
Not specified
Note:
Year
Topic:
Medical Research
Document Type:
Search Strategy
Target Audience:
Researchers, Healthcare Professionals
Year:
2023
Region / city:
Global
Topic:
Spine, Neoplasms, Vertebroplasty, Clinical Trials
Document type:
Research strategy
Institution:
N/A
Author:
N/A
Target audience:
Researchers, clinicians
Period of action:
Ongoing
Approval date:
N/A
Modification date:
N/A
Year:
2017–2021
Medical field:
Sleep medicine
Condition:
Moderate to severe obstructive sleep apnea
Intervention:
Hypoglossal nerve stimulation
Procedure codes:
64582, 64583, 64584
Type of document:
Evidence review and policy summary
Reviewing bodies:
NICE; VbBS; HERC
Last review date:
November 2021
Study types included:
Systematic review; randomized controlled trial; prospective and retrospective case series
Number of studies:
7
Total patients:
326
Geographic context:
United Kingdom; United States
Regulatory context:
Clinical governance and payer policy assessment
Year:
2017
Region / City:
United States
Topic:
Obstructive Sleep Apnea, Commercial Motor Vehicle Drivers, Medical Certification
Document Type:
Medical Examination Recommendation
Organization:
Federal Motor Carrier Safety Administration (FMCSA)
Author:
FMCSA
Target Audience:
Medical professionals, commercial motor vehicle drivers
Effective Period:
2017 and ongoing
Approval Date:
2017
Revision Date:
None
Year:
2023
Region / City:
England
Topic:
Healthcare, Quality Standards
Document Type:
Policy document
Organization / Institution:
NHS England
Author:
General Practice Specification and Extraction Service (GPSES), NHS England
Target Audience:
Healthcare providers, Medical professionals
Period of Validity:
2023-2024
Approval Date:
01/04/2023
Date of Amendments:
01/08/2023
Contextual Description:
Policy document outlining business rules for COPD management under the Quality and Outcomes Framework for NHS England.
Note:
Year
Theme:
Obstructive sleep apnea, Pediatric otolaryngology
Document Type:
Research study
Context:
A research study on physical examination techniques for evaluating tonsil, adenoid, and pharyngeal grading in children with obstructive sleep apnea.
Authors:
David J. Stevens; Sarah L. Appleton; Andrew D. Vincent; Yohannes A. Melaku; Sean A. Martin; Tiffany K. Gill; Catherine L. Hill; Andrew Vakulin; Gary A. Wittert; Robert J. Adams
Document Type:
Supplementary material to a research article
Subject:
Obstructive sleep apnea, nocturnal hypoxemia, grip strength, muscle mass, fat mass
Population:
Community-dwelling middle-aged and older men
Study Design:
Observational study with linear regression analyses
Data Collection Methods:
In-home polysomnography; questionnaires; blood analysis; dual-energy X-ray absorptiometry
Variables Examined:
Age; income; alcohol consumption; smoking; dietary patterns; physical activity; diabetes; hypertension; arthritis; cancer history; cardiovascular disease; depression; muscle mass; fat mass; testosterone; inflammation
Statistical Methods:
Univariate and adjusted linear regression models
Sleep Assessment Device:
Embletta X100 (Embla Systems, Colorado)
Outcome Measures:
Dominant and non-dominant hand grip strength; lean mass; fat mass
Supplement Sections:
Supplementary S1 (regression adjustments and univariate associations); Supplementary S2 (non-respiratory sleep metrics and body composition associations)
Year:
2008–2014
Region / Institution:
HERC, Regence BCBS, SIGN
Subject:
Obstructive Sleep Apnea, Tongue Base Surgery
Document Type:
Clinical Guidelines and Evidence Review
Procedure Codes:
CPT 41512, Excluded Services Guidelines E1–E2
Techniques:
Tongue Base Suspension, Submucosal Ablation
Evidence Sources:
Kezirian 06, Farrar 08, TEC Review 07, Regence BCBS 08
Patient Indications:
Adults with OSA intolerant to CPAP or oral appliances
Outcome Measures:
AHI improvement, Epworth Sleepiness Scale, Functional Outcomes of Sleep Questionnaire
Policy Status:
Experimental, Non-Coverage Recommendations, Medically Necessary under certain criteria
Related Guidelines:
Guideline Notes 172–173, Excluded Services Guidelines 1–2
Surgical Risks:
Not specified in document
Year:
2026
Region / City:
Not specified
Subject:
Obstructive Sleep Apnea Treatment
Document Type:
Clinical Correspondence
Institution:
Dental Sleep Medicine Clinic
Author:
Treating Dentist / Sleep Medicine Specialist
Intended Audience:
Referring Physician
Patient Age / DOB:
As indicated in document
Therapy Initiated:
Oral Appliance Therapy (OAT)
Additional Recommendations:
Weight management, positional therapy, nasal patency improvement
Standards Followed:
American Academy of Dental Sleep Medicine guidelines
Subject:
Cardiovascular diagnostics and coronary artery disease
Topic:
Diagnostic modalities for obstructive epicardial coronary artery disease and coronary microvascular dysfunction
Document type:
Scientific reference tables
Medical field:
Cardiology
Diagnostic categories:
Invasive assessments; Non-invasive assessments
Key conditions addressed:
Obstructive epicardial coronary artery disease; Coronary microvascular dysfunction; Vasospastic angina; Myocardial bridging
Clinical metrics included:
FFR; CFR; IMR; MPR; MBF; CFVR; WMSI; ST-segment depression
Imaging modalities:
CT; Echocardiography; Nuclear SPECT; PET; Perfusion CMR
Physiological testing:
ECG exercise testing; Cardiopulmonary exercise testing; Intracoronary Doppler; Thermodilution methods
Stress agents mentioned:
Adenosine; Dipyridamole; Regadenoson; Dobutamine; Exercise
Clinical availability categories:
Routine; Widely available; Selected centres; Research or academic centre
Reproducibility scale:
low (+); acceptable (++); good (+++)
Reference format:
Supplementary references S1–S63
Associated abbreviations defined:
CAD; FFR; CFR; CMR; PET; SPECT; MBF; MPR; IMR and others
Year:
2026
Region / city:
England, UK
Topic:
Obstructive sleep apnoea, occupational health
Document type:
Research supplementary materials
Institution:
Imperial College London, Royal Brompton Hospital, Guys and St Thomas NHS Foundation Trust
Authors:
Ryohei Kinoshita, Jennifer K Quint, Constantinos Kallis, Michael I Polkey
Target audience:
Epidemiologists, public health researchers, clinicians
Study period:
Data from multiple datasets including SHHS, HSE2019, WSC
Corresponding author contact:
[email protected]
Methodology:
Descriptive study, multiple imputation model, risk factor analysis
Data sources:
SHHS, HSE2019, WSC, literature review from 2010 onwards
Variables analyzed:
Age, sex, ethnicity, obesity, smoking, alcohol, hypertension, diabetes, hyperlipaemia
Content type:
Supplementary tables, study design diagrams, prevalence estimates
Year:
2023
Region / city:
International
Topic:
Cardiovascular research
Document type:
Scientific appendix
Organization:
REDWOOD-HCM, SEQUOIA-HCM, FOREST-HCM Investigators
Author:
Ahmad Masri, MD, MS; Martin S. Maron; Theodore P. Abraham, MD; Michael E. Nassif, MD; Roberto Barriales-Villa, MD; Ozlem Bilen, MD; Caroline J. Coats, MD, PhD; Perry Elliott, MBBS, MD; Pablo Garcia-Pavia, MD PhD; Daniele Massera, MD; Iacopo Olivotto, MD; Artur Oreziak, MD, PhD; Anjali Tiku Owens, MD; Sara Saberi, MD, MS; Scott D. Solomon, MD; Albree Tower-Rader, MD; Stephen B. Heitner, MD; Daniel L. Jacoby, MD; Chiara Melloni, MD, MS; Jenny Wei, PhD; MD; Mark V. Sherrid, MD
Target audience:
Cardiologists, researchers in cardiovascular medicine
Period of validity:
Not specified
Approval date:
Not specified
Date of changes:
Not specified
Year:
2026
Region / city:
Global
Theme:
Sleep apnea, Dry eye disease, Meta-analysis
Document type:
Systematic review, Meta-analysis
Organization:
Not specified
Author:
Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, et al.
Target audience:
Researchers, Medical professionals
Period of validity:
Not specified
Approval date:
Not specified
Date of amendments:
Not specified
Year:
2024
Regulatory authority:
Therapeutic Goods Administration (TGA)
Medicine:
MACITENTAN 10 mg with TADALAFIL 40 mg (Opsynvi®)
Indication:
Pulmonary arterial hypertension (PAH), WHO Group 1, functional class II and III
Therapy type:
Dual or triple combination therapy
Dosage form:
Tablet, fixed dose combination (FDC)
Prescriber type:
Medical practitioners
Restriction type:
Authority Required (Written, Complex Authority Required)
Clinical criteria:
Treatment as dual therapy (MAC+TAD) or triple therapy with prostanoid
Population:
Adult patients with stable PAH on separate doses of macitentan and tadalafil
Previous considerations:
PBAC recommendations for macitentan and tadalafil since 2011–2014
Approval date:
16 September 2024
Source documents:
TGA registration, PBAC meeting minutes, ACM minutes August 2024, FDA, EMA, CDA references