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Scientific cardiology reference tables summarizing invasive and non-invasive diagnostic modalities, metrics, thresholds, availability, and reproducibility for evaluating obstructive epicardial coronary artery disease and ischaemia not attributable to obstructive epicardial disease.
Subject: Cardiovascular diagnostics and coronary artery disease
Topic: Diagnostic modalities for obstructive epicardial coronary artery disease and coronary microvascular dysfunction
Document type: Scientific reference tables
Medical field: Cardiology
Diagnostic categories: Invasive assessments; Non-invasive assessments
Key conditions addressed: Obstructive epicardial coronary artery disease; Coronary microvascular dysfunction; Vasospastic angina; Myocardial bridging
Clinical metrics included: FFR; CFR; IMR; MPR; MBF; CFVR; WMSI; ST-segment depression
Imaging modalities: CT; Echocardiography; Nuclear SPECT; PET; Perfusion CMR
Physiological testing: ECG exercise testing; Cardiopulmonary exercise testing; Intracoronary Doppler; Thermodilution methods
Stress agents mentioned: Adenosine; Dipyridamole; Regadenoson; Dobutamine; Exercise
Clinical availability categories: Routine; Widely available; Selected centres; Research or academic centre
Reproducibility scale: low (+); acceptable (++); good (+++)
Reference format: Supplementary references S1–S63
Associated abbreviations defined: CAD; FFR; CFR; CMR; PET; SPECT; MBF; MPR; IMR and others
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Supplementary Information: Therapeutic Potential of MSCs and Their Exosomes in Hepatic Ischaemia Reperfusion Injury — A Systematic Review and Meta-Analysis of Rodent Studies
Authors: Yanxi Mu; Weixiong Zhu; Wentao Ma; Yu Cheng; Bo Ren; Yusheng Cheng; Wence Zhou
Affiliations: The Second Clinical Medical College, Lanzhou University, Lanzhou, China; Department of General Surgery, Biotherapy, Lanzhou University Second Hospital, Lanzhou, China; Gansu Province Precision Diagnosis and Treatment Engineering Research Center of Hepatobiliary Pancreatic Diseases; Gansu Province Key Laboratory of Environmental Oncology, Lanzhou, China
Corresponding authors: Yusheng Cheng; Wence Zhou
Running head: MSCs and Exosome Therapy in HIRI
Type of document: Supplementary information to a systematic review and meta-analysis
Subject: Mesenchymal stem cells and exosomes in hepatic ischaemia reperfusion injury
Study design: Systematic review and meta-analysis of rodent studies
Databases searched: PubMed; Web of Science; Embase; Cochrane Library; ClinicalTrials.gov
Outcomes assessed: ALT; AST; Suzuki’s score; necrotic area ratio; serum TNF-α; cleaved caspase-3
Experimental model: 70% hepatic ischaemia reperfusion injury with 60 or 90 minutes of ischemia in rodents
Content elements: Funnel plots; forest plots; search strategies; summary of mechanisms and outcome data
Novel IL-4/HB-EGF-Dependent Crosstalk between Eosinophils and Macrophages Controls Liver Regeneration after Ischaemia and Reperfusion Injury (2024)
Year: 2024
Journal: Gut
Volume: 73
Pages: 1543–1553
DOI: 10.1136/gutjnl-2024-332033
Authors: Yang Y; Xu L; Atkins C; et al.
Topic: Liver regeneration; ischaemia reperfusion injury; immunology; transplantation
Study Type: Experimental research article
Model System: Mouse models of liver injury
Key Molecules: IL-4; IL-13; IL-4Rα; HB-EGF; EGFR
Injury Models: Ischaemia reperfusion injury; paracetamol-induced injury; carbon tetrachloride-induced injury
Smoking attributable mortality and hospital admissions for Wales, 2020-22
Year: 2020-2022
Region / City: Wales
Topic: Smoking-related health outcomes
Document Type: Report
Organization / Institution: Public Health Wales
Author: Chris Emmerson, Hugo Cosh, Bethan Patterson, Rebecca Hughes
Target Audience: Public health stakeholders, local health boards, government agencies
Period of validity: 2020-2022
Approval Date: 24 September 2024
Date of amendments: Not specified
Supplementary Table S2. Trends in Age-Standardized Mortality, DALY, YLD, and YLL Rates (per 100,000 Persons) by Sex, 1990–2021, for Total Cancer Attributable to Occupational Asbestos Exposure in China
Country: China
Subject: Total cancer attributable to occupational asbestos exposure
Indicators: Age-standardized mortality rate; Age-standardized DALY rate; Age-standardized YLD rate; Age-standardized YLL rate
Population: Both sexes, females, and males
Period covered: 1990–2021
Statistical measures: APC (annual percent change); AAPC (average annual percent change); 95% CI (confidence interval)
Unit of measurement: Rates per 100,000 persons
Significance threshold: p < 0.05
Abbreviations: DALYs (disability-adjusted life-years); YLDs (years lived with disability); YLLs (years of life lost); AAPC (average annual percent change); APC (annual percent change); CI (confidence interval)
Supplemental item S1. Part 1: Modelling the relationship between daily temperature and cause-specific mortality and estimating the attributable burden of disease
Year: 2020
Region / city: Global
Theme: Public Health, Climate Change
Document Type: Research Study
Author: Not specified
Target audience: Researchers, Public Health Professionals
Period of validity: 1980-2019
Date of approval: Not specified
Date of changes: Not specified
Data Source: ERA5, WorldPop, GBD 2019
Keywords: Temperature, Mortality, Climate Change, Disease Burden, Public Health
Methodology: Meta-regression, Bayesian, Spline modeling, Comparative Risk Assessment
Note: Description
Topics: Epicardial Ischaemia attributable