№ files_lp_4_process_1_49799
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Formal communication from a dental sleep medicine clinic detailing a patient’s initiation of oral appliance therapy for obstructive sleep apnea, including assessment, plan, and follow-up recommendations for the referring physician.
Year:
2026
Region / City:
Not specified
Subject:
Obstructive Sleep Apnea Treatment
Document Type:
Clinical Correspondence
Institution:
Dental Sleep Medicine Clinic
Author:
Treating Dentist / Sleep Medicine Specialist
Intended Audience:
Referring Physician
Patient Age / DOB:
As indicated in document
Therapy Initiated:
Oral Appliance Therapy (OAT)
Additional Recommendations:
Weight management, positional therapy, nasal patency improvement
Standards Followed:
American Academy of Dental Sleep Medicine guidelines
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The product description is provided for reference. Actual content and formatting may differ slightly.
Year:
2017–2021
Medical field:
Sleep medicine
Condition:
Moderate to severe obstructive sleep apnea
Intervention:
Hypoglossal nerve stimulation
Procedure codes:
64582, 64583, 64584
Type of document:
Evidence review and policy summary
Reviewing bodies:
NICE; VbBS; HERC
Last review date:
November 2021
Study types included:
Systematic review; randomized controlled trial; prospective and retrospective case series
Number of studies:
7
Total patients:
326
Geographic context:
United Kingdom; United States
Regulatory context:
Clinical governance and payer policy assessment
Year:
2017
Region / City:
United States
Topic:
Obstructive Sleep Apnea, Commercial Motor Vehicle Drivers, Medical Certification
Document Type:
Medical Examination Recommendation
Organization:
Federal Motor Carrier Safety Administration (FMCSA)
Author:
FMCSA
Target Audience:
Medical professionals, commercial motor vehicle drivers
Effective Period:
2017 and ongoing
Approval Date:
2017
Revision Date:
None
Year:
[Year]
Region / City:
[City]
Theme:
Medical Opinion
Document Type:
Independent Medical Opinion
Organization / Institution:
[Medical Facility Name]
Author:
Dr. Grant Thomas
Target Audience:
Healthcare providers, VA personnel
Period of validity:
N/A
Approval Date:
N/A
Date of Changes:
N/A
Note:
Date
Topic:
Medical Opinion
Document Type:
Independent Medical Opinion
Author:
[Physician’s Name]
Target Audience:
Veterans Affairs (VA) Review Boards, Healthcare Providers
Note:
Year
Theme:
Obstructive sleep apnea, Pediatric otolaryngology
Document Type:
Research study
Context:
A research study on physical examination techniques for evaluating tonsil, adenoid, and pharyngeal grading in children with obstructive sleep apnea.
Authors:
David J. Stevens; Sarah L. Appleton; Andrew D. Vincent; Yohannes A. Melaku; Sean A. Martin; Tiffany K. Gill; Catherine L. Hill; Andrew Vakulin; Gary A. Wittert; Robert J. Adams
Document Type:
Supplementary material to a research article
Subject:
Obstructive sleep apnea, nocturnal hypoxemia, grip strength, muscle mass, fat mass
Population:
Community-dwelling middle-aged and older men
Study Design:
Observational study with linear regression analyses
Data Collection Methods:
In-home polysomnography; questionnaires; blood analysis; dual-energy X-ray absorptiometry
Variables Examined:
Age; income; alcohol consumption; smoking; dietary patterns; physical activity; diabetes; hypertension; arthritis; cancer history; cardiovascular disease; depression; muscle mass; fat mass; testosterone; inflammation
Statistical Methods:
Univariate and adjusted linear regression models
Sleep Assessment Device:
Embletta X100 (Embla Systems, Colorado)
Outcome Measures:
Dominant and non-dominant hand grip strength; lean mass; fat mass
Supplement Sections:
Supplementary S1 (regression adjustments and univariate associations); Supplementary S2 (non-respiratory sleep metrics and body composition associations)
Year:
2008–2014
Region / Institution:
HERC, Regence BCBS, SIGN
Subject:
Obstructive Sleep Apnea, Tongue Base Surgery
Document Type:
Clinical Guidelines and Evidence Review
Procedure Codes:
CPT 41512, Excluded Services Guidelines E1–E2
Techniques:
Tongue Base Suspension, Submucosal Ablation
Evidence Sources:
Kezirian 06, Farrar 08, TEC Review 07, Regence BCBS 08
Patient Indications:
Adults with OSA intolerant to CPAP or oral appliances
Outcome Measures:
AHI improvement, Epworth Sleepiness Scale, Functional Outcomes of Sleep Questionnaire
Policy Status:
Experimental, Non-Coverage Recommendations, Medically Necessary under certain criteria
Related Guidelines:
Guideline Notes 172–173, Excluded Services Guidelines 1–2
Surgical Risks:
Not specified in document
Year:
2026
Region / city:
Global
Theme:
Sleep apnea, Dry eye disease, Meta-analysis
Document type:
Systematic review, Meta-analysis
Organization:
Not specified
Author:
Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, et al.
Target audience:
Researchers, Medical professionals
Period of validity:
Not specified
Approval date:
Not specified
Date of amendments:
Not specified
Year:
2026
Location:
Hotel Nikko, San Francisco, CA, USA
Topic:
Sleep Apnea, Snoring, Sleep Disorders
Document Type:
Educational Conference Program
Organizing Institutions:
University of California, San Francisco Department of Otolaryngology-Head and Neck Surgery; Penn Center for Sleep Disorders, University of Pennsylvania
Authors / Faculty:
Andrew N Goldberg, MD; Eric J Kezirian, MD; Richard J Schwab, MD; Jolie L Chang, MD; David M Claman, MD; plus additional UCSF and external faculty
Intended Audience:
Healthcare professionals including physicians, nurses, and physician assistants
Accreditation:
AMA PRA Category 1 Credits™, ANCC Contact Hours, AAPA Category 1 CME Credits, Interprofessional Continuing Education (IPCE)
Educational Objectives:
Review new developments in diagnosis, management, and treatment of sleep apnea and snoring; evaluate medical and surgical interventions; assess patient outcomes and technology impact
Commercial Support:
Eli Lilly, Neurocare, Inc, Reflux Gourmet, Sleep Res Inc
Exhibitors:
Aerin Medical, Apnimed, Avadel, Axsome Therapeutics, Cadwell, Clevemed, Cryosa, DayBreak, Eli Lilly, Ensodata, Fisher & Paykel, Harmony Bioscience, Inspire, Jazz Pharma, Livanova, Moona Health, Neilmed, Nox Medical, Nyxoah, Onera, Philips, Ron Andrews Medical Company, Serene Sleep, Sleep Res, Vertex Pharmaceuticals, Zoll Itamar
Course Chairs:
Andrew N. Goldberg, MD; Jolie L. Chang, MD; David M. Claman, MD; Eric J. Kezirian, MD; Richard J. Schwab, MD
Year:
2017–2021
Medical field:
Sleep medicine
Condition:
Moderate to severe obstructive sleep apnea
Intervention:
Hypoglossal nerve stimulation
Procedure codes:
64582, 64583, 64584
Type of document:
Evidence review and policy summary
Reviewing bodies:
NICE; VbBS; HERC
Last review date:
November 2021
Study types included:
Systematic review; randomized controlled trial; prospective and retrospective case series
Number of studies:
7
Total patients:
326
Geographic context:
United Kingdom; United States
Regulatory context:
Clinical governance and payer policy assessment
Year:
2017
Region / City:
United States
Topic:
Obstructive Sleep Apnea, Commercial Motor Vehicle Drivers, Medical Certification
Document Type:
Medical Examination Recommendation
Organization:
Federal Motor Carrier Safety Administration (FMCSA)
Author:
FMCSA
Target Audience:
Medical professionals, commercial motor vehicle drivers
Effective Period:
2017 and ongoing
Approval Date:
2017
Revision Date:
None
Year:
2023
Region / City:
England
Topic:
Healthcare, Quality Standards
Document Type:
Policy document
Organization / Institution:
NHS England
Author:
General Practice Specification and Extraction Service (GPSES), NHS England
Target Audience:
Healthcare providers, Medical professionals
Period of Validity:
2023-2024
Approval Date:
01/04/2023
Date of Amendments:
01/08/2023
Contextual Description:
Policy document outlining business rules for COPD management under the Quality and Outcomes Framework for NHS England.
Note:
Year
Theme:
Obstructive sleep apnea, Pediatric otolaryngology
Document Type:
Research study
Context:
A research study on physical examination techniques for evaluating tonsil, adenoid, and pharyngeal grading in children with obstructive sleep apnea.
Authors:
David J. Stevens; Sarah L. Appleton; Andrew D. Vincent; Yohannes A. Melaku; Sean A. Martin; Tiffany K. Gill; Catherine L. Hill; Andrew Vakulin; Gary A. Wittert; Robert J. Adams
Document Type:
Supplementary material to a research article
Subject:
Obstructive sleep apnea, nocturnal hypoxemia, grip strength, muscle mass, fat mass
Population:
Community-dwelling middle-aged and older men
Study Design:
Observational study with linear regression analyses
Data Collection Methods:
In-home polysomnography; questionnaires; blood analysis; dual-energy X-ray absorptiometry
Variables Examined:
Age; income; alcohol consumption; smoking; dietary patterns; physical activity; diabetes; hypertension; arthritis; cancer history; cardiovascular disease; depression; muscle mass; fat mass; testosterone; inflammation
Statistical Methods:
Univariate and adjusted linear regression models
Sleep Assessment Device:
Embletta X100 (Embla Systems, Colorado)
Outcome Measures:
Dominant and non-dominant hand grip strength; lean mass; fat mass
Supplement Sections:
Supplementary S1 (regression adjustments and univariate associations); Supplementary S2 (non-respiratory sleep metrics and body composition associations)
Year:
2008–2014
Region / Institution:
HERC, Regence BCBS, SIGN
Subject:
Obstructive Sleep Apnea, Tongue Base Surgery
Document Type:
Clinical Guidelines and Evidence Review
Procedure Codes:
CPT 41512, Excluded Services Guidelines E1–E2
Techniques:
Tongue Base Suspension, Submucosal Ablation
Evidence Sources:
Kezirian 06, Farrar 08, TEC Review 07, Regence BCBS 08
Patient Indications:
Adults with OSA intolerant to CPAP or oral appliances
Outcome Measures:
AHI improvement, Epworth Sleepiness Scale, Functional Outcomes of Sleep Questionnaire
Policy Status:
Experimental, Non-Coverage Recommendations, Medically Necessary under certain criteria
Related Guidelines:
Guideline Notes 172–173, Excluded Services Guidelines 1–2
Surgical Risks:
Not specified in document
Subject:
Cardiovascular diagnostics and coronary artery disease
Topic:
Diagnostic modalities for obstructive epicardial coronary artery disease and coronary microvascular dysfunction
Document type:
Scientific reference tables
Medical field:
Cardiology
Diagnostic categories:
Invasive assessments; Non-invasive assessments
Key conditions addressed:
Obstructive epicardial coronary artery disease; Coronary microvascular dysfunction; Vasospastic angina; Myocardial bridging
Clinical metrics included:
FFR; CFR; IMR; MPR; MBF; CFVR; WMSI; ST-segment depression
Imaging modalities:
CT; Echocardiography; Nuclear SPECT; PET; Perfusion CMR
Physiological testing:
ECG exercise testing; Cardiopulmonary exercise testing; Intracoronary Doppler; Thermodilution methods
Stress agents mentioned:
Adenosine; Dipyridamole; Regadenoson; Dobutamine; Exercise
Clinical availability categories:
Routine; Widely available; Selected centres; Research or academic centre
Reproducibility scale:
low (+); acceptable (++); good (+++)
Reference format:
Supplementary references S1–S63
Associated abbreviations defined:
CAD; FFR; CFR; CMR; PET; SPECT; MBF; MPR; IMR and others
Year:
2026
Region / city:
England, UK
Topic:
Obstructive sleep apnoea, occupational health
Document type:
Research supplementary materials
Institution:
Imperial College London, Royal Brompton Hospital, Guys and St Thomas NHS Foundation Trust
Authors:
Ryohei Kinoshita, Jennifer K Quint, Constantinos Kallis, Michael I Polkey
Target audience:
Epidemiologists, public health researchers, clinicians
Study period:
Data from multiple datasets including SHHS, HSE2019, WSC
Corresponding author contact:
[email protected]
Methodology:
Descriptive study, multiple imputation model, risk factor analysis
Data sources:
SHHS, HSE2019, WSC, literature review from 2010 onwards
Variables analyzed:
Age, sex, ethnicity, obesity, smoking, alcohol, hypertension, diabetes, hyperlipaemia
Content type:
Supplementary tables, study design diagrams, prevalence estimates
Year:
2023
Region / city:
International
Topic:
Cardiovascular research
Document type:
Scientific appendix
Organization:
REDWOOD-HCM, SEQUOIA-HCM, FOREST-HCM Investigators
Author:
Ahmad Masri, MD, MS; Martin S. Maron; Theodore P. Abraham, MD; Michael E. Nassif, MD; Roberto Barriales-Villa, MD; Ozlem Bilen, MD; Caroline J. Coats, MD, PhD; Perry Elliott, MBBS, MD; Pablo Garcia-Pavia, MD PhD; Daniele Massera, MD; Iacopo Olivotto, MD; Artur Oreziak, MD, PhD; Anjali Tiku Owens, MD; Sara Saberi, MD, MS; Scott D. Solomon, MD; Albree Tower-Rader, MD; Stephen B. Heitner, MD; Daniel L. Jacoby, MD; Chiara Melloni, MD, MS; Jenny Wei, PhD; MD; Mark V. Sherrid, MD
Target audience:
Cardiologists, researchers in cardiovascular medicine
Period of validity:
Not specified
Approval date:
Not specified
Date of changes:
Not specified
Year:
2026
Region / city:
Global
Theme:
Sleep apnea, Dry eye disease, Meta-analysis
Document type:
Systematic review, Meta-analysis
Organization:
Not specified
Author:
Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, et al.
Target audience:
Researchers, Medical professionals
Period of validity:
Not specified
Approval date:
Not specified
Date of amendments:
Not specified
Database:
MEDLINE
Subject area:
Pulmonary medicine and rehabilitation
Research topic:
Chronic obstructive pulmonary disease and rehabilitation interventions
Document type:
Literature search strategy
Methodology:
Randomized controlled trials and controlled clinical trials
Health condition:
Chronic obstructive pulmonary disease (COPD) and pulmonary emphysema
Intervention types:
Rehabilitation, physiotherapy, physical therapy, exercise training, breathing exercises
Search components:
Disease terms, rehabilitation and exercise terms, randomized trial filters
Search structure:
Boolean logic combining disease, intervention, and trial methodology terms
Population scope:
Human subjects
Purpose:
Identification of clinical trials on rehabilitation and exercise interventions in COPD