№ files_lp_4_process_3_112443
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This document presents proposed optics configurations for the 2012 LHC proton run, detailing the necessary adjustments for improved beam parameters, collimator settings, and high-beta optics scenarios.
Year:
2012
Region / city:
Geneva, Switzerland
Topic:
Particle physics, LHC, proton run
Document type:
Technical report
Organization / institution:
CERN
Author:
M. Giovannozzi
Target audience:
Particle physicists, accelerator specialists
Period of validity:
2012
Approval date:
2012
Modification date:
Not specified
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Year:
2013
Region / City:
Cambridge, MA
Topic:
Energy Conversion, Catalysis
Document Type:
Research Paper
Organization / Institution:
Massachusetts Institute of Technology
Author:
Yogesh Surendranath
Target Audience:
Researchers, Academics
Period of Activity:
2013 - Present
Date of Approval:
N/A
Date of Changes:
N/A
Document type:
Supplementary tables and figures
Subject:
Proton therapy and VMAT treatment planning and dosimetric analysis
Techniques evaluated:
IMPT, VMAT
Clinical indications:
Base of skull tumors, paediatric craniopharyngioma, chordoma, chondrosarcoma
Structures analyzed:
Brain, Brainstem, Optic chiasm, Optic nerves, CTV
Dose metrics:
Mean dose, Maximum dose, EQD2, BED, LETd
Robustness parameters:
Isocenter shifts ±3.0 mm; Proton range uncertainty ±3.5%
Fractionation scheme:
1.67 Gy(RBE) fractions
Constraint source:
EPTN dose constraints
Number of patients:
6 adult cases
Comparative models:
Nominal IMPT, Worst case IMPT uncertainty, VMAT, McNamara variable RBE model (α/β)x = 2–4 Gy
Figures included:
Beam arrangement views, dose distributions, LETd maps, DVHs, robustness analysis
Year:
2025–2030
Region / City:
Marlborough, Worcester County, Massachusetts
Organization:
UMass Memorial Health (UMMH)
Facility:
Proton Therapy Center at Marlborough
Document Type:
Application Response / Capacity and Policy Explanation
Subject:
Proton Beam Unit Capacity and Coverage with Evidence Development (CED) Paradigm
Operational Hours:
14 hours per day, Monday through Friday
Days of Operation per Year:
250
Projected Daily Capacity:
30 treatments
Projected Monthly Capacity:
600 treatments
Projected Annual Capacity:
7,200 treatments
Average Treatment Time per Patient:
30 minutes (Year 1); 25 minutes (Years 2–3)
Estimated Annual Radiation Treatments:
4,320 (Year 1); 7,200 (Years 2–3)
Estimated Patient Volume (New Starts):
180 (Year 1); 300 (Years 2–3)
Average Treatments per Patient:
24
Total Estimated Treatment Minutes:
129,600 (Year 1); 180,000 (Years 2–3)
Policy Framework:
ASTRO Model Policy and Medicare Local Coverage Determination (LCD) L35075
Coverage Model:
Coverage with Evidence Development (CED)
Clinical Trial Participation:
Participation in IRB-approved clinical trials and multi-institutional registries; planned investigator-initiated trials
Payor Mix:
54.9% Medicare (projected)
Coverage Groups:
Group 1 (medically necessary indications); Group 2 (CED-qualified indications)
Year:
2025
Region / City:
Marlborough, Massachusetts
Subject:
Proton Therapy Expansion
Document Type:
Health Initiative Proposal
Organization:
UMass Memorial Health
Author:
UMass Memorial Health
Target Audience:
Healthcare professionals, policymakers, cancer patients, public health officials
Period of Action:
Ongoing
Approval Date:
N/A
Modification Date:
N/A
Year:
2026
Institution:
University of Shanghai for Science and Technology; Shanghai Institute of Optics and Fine Mechanics, Chinese Academy of Sciences; Shanghai Normal University; ShanghaiTech University
Authors:
Xiaojing Guo, Shuai Xu, Hui Zhang, Qingsong Wang, Shun Li, Dirui Xu, Lianghong Yu, Yi Xu, Cheng Wang, Xingyan Liu, Yanqi Liu, Xiaoyan Liang, Yuxin Leng, Baifei Shen, Liangliang Ji, Ruxin Li
Type of document:
Supplementary material
Subject:
Laser-driven proton acceleration; Femtosecond lasers; Plasma physics
Corresponding authors:
Hui Zhang, Baifei Shen, Liangliang Ji
Figures included:
Proton energy spectra, hydrodynamic simulation inputs, preplasma density distributions, simulated proton spectra
Data source:
RCF measurements, 1D hydrodynamic simulations
Experimental scale:
Nanosecond and picosecond prepulse simulations
Year:
2026
Region / City:
Boston, Massachusetts, USA
Subject:
Healthcare infrastructure, proton therapy
Document Type:
Public hearing transcript
Organization / Agency:
Massachusetts Department of Public Health, Bureau of Health Care Safety and Quality
Author:
Hearing Officer Teryl Smith, Lucy Clarke, various speakers
Intended Audience:
General public, healthcare stakeholders
Project Location:
35 Binney Street, Boston, Massachusetts
Project Scope:
Renovation, fit-out, and installation of proton therapy system including CT scanners and clinical support areas
Estimated Budget:
$50,500,663
Date of Hearing:
January 14, 2026
Filing Date of Application:
November 19, 2025
Regulatory Program:
Determination of Need (DoN)
Year:
FY24
Region / State:
Massachusetts
Topic:
Proton Beam Therapy; Patient Panel Need Assessment
Document Type:
Questionnaire / Data Request
Institution:
Massachusetts Department of Public Health
Program:
Determination of Need (DoN) Program
Submitting Authority:
DoN Staff
Contact Email:
[email protected]
Relevant Regulation:
HIPAA Compliance
Subject:
Patient Panel Eligibility and Diagnosis Counts
Medical Classification System:
ICD-10 Diagnosis Codes
Population Groups:
Adult; Pediatric
Data Format Requested:
Word; Excel; PDF (if necessary)
Required Attachment:
Exhibit A
Content Elements:
Diagnosis Codes; Diagnosis Descriptions; Patient Counts
Year:
2026
Institution:
Radiation Oncology Department
Document type:
Clinical Supplement
Subject:
Proton Therapy Beam Parameters
Audience:
Medical Physicists, Radiation Oncologists
Data included:
Maximum proton energy, gantry angle, monitor units, energy layers, beam delivery time
Number of cases:
5
Beam types:
Beam A / Beam B
Year:
2023
Institution:
California Institute of Technology
Department:
LIGO
Document Type:
Statement of Work
Author:
Lee McCuller
Project:
GQuEST optical cavity experiment
Target Wavelengths:
1550 nm, 775 nm
Mirror Types:
M1 (coating-A), M2 (coating-B), M3 (coating-B), M4 (coating-B)
Quantity:
24 M1, 16 M2, 8 M3, 8 M4
Delivery Location:
Pasadena, CA, USA
Special Requirements:
Optical quality matching, transmission tolerance, inspection standards, packaging instructions
Document type:
Press release
Date:
November 19, 2024
Place of publication:
Singapore
Company:
ASMPT Limited
Division:
ASMPT Semiconductor Solutions (ASMPT SEMI)
Product:
AMICRA NANO
Topic:
Hybrid bonding and co-packaged optics manufacturing
Industry:
Semiconductor assembly and packaging
Spokesperson:
Dr. Johann Weinhändler
Contact information:
Global ASMPT Semiconductor Solutions Press Office; Global ASMPT Press Office
Year:
2020
Region / City:
Not specified
Topic:
Medical Imaging, Software Development
Document Type:
Software Documentation
Organization / Institution:
Not specified
Author:
Jianfei Liu, Yoo-Jean Han, Tao Liu, Nancy Aguilera, Johnny Tam
Target Audience:
Researchers, Developers, Medical Professionals
Period of Validity:
Not specified
Approval Date:
Not specified
Modification Date:
Not specified
Title:
Questions from Bill Nye Light Optics Video with Answer Key
Type of document:
Educational worksheet and quiz
Subject:
Light optics
Related media:
Bill Nye Light Optics Video
Format:
Question sheet with multiple choice and true/false sections
Includes:
Answer key with pause times
Educational level:
Not specified
Topics covered:
Reflection, refraction, absorption, mirrors, lenses, infrared light, fiber optics, internal reflection
Year:
2024
Region / City:
International
Topic:
Research, Magnetics, Magneto-Optical Phenomena, Thermo-Magnetic Phenomena
Document Type:
Submission Guidelines
Organization:
MORIS
Author:
Not specified
Target Audience:
Researchers, Conference Attendees
Period of Validity:
Until 31 January 2024
Approval Date:
Not specified
Date of Changes:
Not specified
Year:
2025
Region / City:
Cork, Ireland
Topic:
Biotechnology, Medicine, Surgery, Optics
Document Type:
Conference Program
Organ / Institution:
Engineering Conferences International
Authors:
Stefan Andersson-Engels, Summer Gibbs, Melissa Skala
Target Audience:
Researchers, professionals in optics, biotechnology, and medical fields
Period of Validity:
May 18 - 22, 2025
Date of Approval:
2025
Date of Changes:
N/A
Language:
English
Subject:
Physics and Earth Science
Topics:
Sonar, Moon rotation and orbit, Rainbow formation, Refraction, Diffraction, Atmospheric scattering, Wave behavior
Type of document:
Educational informational text
Intended audience:
General readers and students
Scientific fields:
Acoustics, Optics, Astronomy, Oceanography
Key concepts:
Echo, Wavelength, Frequency, Light scattering, Wave bending, Atmospheric interaction
Phenomena described:
Low-frequency sonar, Lunar phases, Refraction in water, Diffraction of sound and water waves, Red sunsets, Cloud coloration
Note:
Year
Region / City:
Adelaide, SA (Brisbane or Hobart considered)
Subject:
Applied Optics, Water Quality Monitoring
Document Type:
Job Advertisement
Organization / Institution:
CSIRO
Author:
CSIRO
Target Audience:
Australian/New Zealand Citizens; Australian Permanent Residents; Australian temporary residents currently residing in Australia
Period of Validity:
3 years
Approval Date:
Not specified
Modification Date:
Not specified
Institution:
DPG Institute of Technology and Management
Location:
Sector 34, Gurugram, Haryana, India
Course Name:
Fiber Optics Communication
Course Code:
PCC-ECE 401G
Faculty:
Ms Gulrukh
Lecture Hours per Week:
3
Total Lecture Hours:
30
Exam Duration:
03 Hours
Exam Marks:
75
Course Objectives:
Understanding optical communication systems, optical network elements, modulation schemes, and planning and budgeting of optical communication systems
Course Units:
Optical communication fundamentals; Light sources and detectors; Optical link design and amplification; Non-linear effects in fiber links
Teaching Methods:
Lectures with interaction, video presentations, discussions, quizzes, assignments, guest lectures
Learning Activities:
Question and answer sessions, quizzes, discussions, whiteboard demonstrations, reference material analysis
Recommended Textbook:
Optical Fiber Communications by John M. Senior
Reference Books:
Optical Communication Systems by John Gowar; Optical Fiber Communications by Gerd Keiser
Course Outcomes:
Explanation of optical communication theory, system components, fiber losses and link budgeting, and operation of optical amplifiers
Additional Course:
Basic Electronics
Topics Covered in Additional Course:
Semiconductor theory, PN junction diodes, rectifiers, transistor operation, biasing techniques, amplifier models, FETs and MOSFETs, optoelectronic devices, SCR, TRIAC, DIAC, IGBT, optocouplers
Primary Textbook for Additional Course:
Basic Electronics by Debashis De
Reference Books for Additional Course:
Electronic Devices and Circuits by Robert Boylestad; Electronic Device Circuits by David A. Bell; Integrated Electronics by Millman and Halkias; Electronic Devices and Circuit by Dharam Raj Cheruku
Assessment Structure:
Course outcome and program outcome mapping tables included
Approval:
Signature of Staff In-charge and Head of Department indicated
Year:
2026
Institution:
Center for Biomedical Optics and Photonics, College of Physics and Optoelectric Engineering, Shenzhen University
Authors:
Chenshuang Zhang, Yong Zhang, Danying Lin, Bin Yu, Junle Qu
Field:
Biomedical imaging, Optical microscopy
Document type:
Research article
Target audience:
Neuroscientists, biomedical researchers
Methodology:
Adaptive optics-based multi-focus structured illumination microscopy (AO-MSIM)
Key findings:
Achieved 150nm spatial resolution at 500μm depth in thick brain tissue
Correspondence:
[email protected]
Year:
2023
Author:
L. McCuller
Document type:
Technical specification
Material:
Corning HPFS 7980 (high purity fused silica, UV grade)
Mirror dimensions:
Diameter 25.4mm, Thickness 6.35mm, Wedge 30 arcmin ±5 arcmin
Mirror types:
M1 Flat-Flat, M2 Flat-Flat, M3 Flat-Concave, M4 Flat-Concave
Surface quality:
Side 1 <1Å central 80%, Side 2 <5Å central 80%
Coating:
Ion Beam Sputtered, high damage threshold, low scatter and absorption
Wavelengths:
1550nm, 775nm
Polarization:
S & P
Application:
Cavity mirrors for optical setups
AOI:
0–6 degrees (nominal 3 degrees)
Vendor requirements:
Spectrophotometer graphs for AR and HR coatings