№ files_lp_4_process_1_28111
Comprehensive meta-analysis of hepatocellular carcinoma samples identifying correlations between consensus driver gene mutations and clinical, molecular, and survival outcomes.
Year: 2026
Region / City: Honolulu, HI, USA; Ann Arbor, MI, USA
Topic: Hepatocellular carcinoma genetics
Document type: Research article
Institution: University of Hawaii Cancer Center; University of Michigan
Authors: Kumardeep Chaudhary, Olivier B Poirion, Liangqun Lu, Sijia Huang, Travers Ching, Lana X Garmire
Funding: NIEHS K01ES025434, P20 COBRE GM103457, NICHD R01 HD084633, NLM R01LM012373, Hawaii Community Foundation 14ADVC-64566
Target audience: Biomedical researchers, oncologists, bioinformaticians
Methods: Multi-modal meta-analysis, mutation profiling, Kaplan-Meier survival analysis, bipartite graph analysis
Sample size: 1494 HCC samples across 6 cohorts
Key findings: Associations of consensus driver genes with phenotypes, miR expression, CNV, and overall survival
Supplementary materials: Figures S1–S8, Table S1, File S1
Document type of source: Peer-reviewed scientific publication
Price: 8 / 10 USD
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