№ lp_1_16620
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This document outlines a policy for the delegation of insulin administration to adults with Type 2 diabetes in community settings, aiming to ensure safe and consistent practices in line with national standards.
Year:
2022
Region / City:
England
Topic:
Healthcare, Insulin Administration
Document Type:
Policy
Organization / Institution:
NHS England and Improvement (NHSEI)
Author:
Not specified
Target Audience:
Healthcare workers, support workers, non-regulated health and care roles, allied health professionals
Period of validity:
Not specified
Approval date:
November 2022
Date of changes:
Not specified
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Year:
2018
Region / City:
London
Topic:
Diabulimia, Integrated Diabetes and Mental Health Pathway
Document Type:
Response Template
Organization:
NHS England
Author:
Not specified
Target Audience:
Health providers, commissioners
Period of Implementation:
15 months
Approval Date:
Not specified
Amendment Date:
Not specified
Year:
2026
Organization:
Canberra Health Services
Department:
Neonatology
Document Type:
Procedure
Target Audience:
Medical Officers, Registered Nurses, Midwives, Student Nurses under supervision
Scope:
Neonates from birth to 44 weeks corrected gestational age
Related Policies:
Neonatal Intensive Care Drug Manual, ANMF guidelines
Definitions Included:
Blood Glucose Levels, Hyperglycaemia, Significant Hyperglycaemia
Treatment Recommendations:
Insulin infusion, glucose monitoring, TPN and enteral feeding guidance
Risks Addressed:
Hypoglycaemia, glucose delivery variability, insulin-plastic binding
Year:
2022
Region / City:
ACT and surrounding NSW
Topic:
Paediatric Diabetes Care, Insulin Pump Therapy
Document Type:
Clinical Guideline
Organization:
Canberra Health Services (CHS)
Author:
Canberra Health Services, Paediatric Endocrinology and Diabetes Service
Target Audience:
Paediatric Diabetes Healthcare Providers
Period of Validity:
N/A
Approval Date:
N/A
Date of Last Revision:
N/A
Note:
Year
Region / city:
Canberra
Topic:
High-Risk Medicines, Insulin Administration
Document Type:
Procedure
Institution:
Canberra Health Services
Target Audience:
CHS Employees (Medical, Nursing, Midwifery, Pharmacy, Allied Health)
Year:
2026
Region / city:
Canberra
Topic:
Insulin infusion management in hospital settings
Document type:
Procedure
Organization / institution:
Canberra Health Services
Author:
Not specified
Target audience:
Medical officers, nurses, midwives, ICU/HDU/ED staff at North Canberra Hospital
Effective period:
Not specified
Approval date:
Not specified
Revision date:
Not specified
Year:
2025
Region / City:
Tower Hamlets, Newham, Bedfordshire
Topic:
Diabetes care, insulin administration, healthcare policy
Document type:
Policy
Organization:
East London NHS Foundation Trust
Author:
Georgina Amparado Molina, Michael Asuma, Caroline Ogunsola
Target Audience:
Healthcare professionals, clinical staff
Effective period:
May 2025 – May 2028
Approval date:
14th May 2025
Date of last review:
May 2025
Date of next review:
May 2028
Version:
6
Issuing organisation:
Frimley Integrated Care System
Region:
Frimley ICS
Country:
United Kingdom
Document status:
Controlled document
Review date:
August 2025
Key topics:
Hybrid Closed Loop systems, insulin pump therapy, continuous glucose monitoring
Clinical area:
Paediatric type 1 diabetes
Target population:
Children and young people with type 1 diabetes
Relevant guidance:
NICE Technology Appraisal TA943
Care setting:
Specialist Diabetes Service
Multidisciplinary team involvement:
Yes
Implementation scope:
NHS England services
Document title:
Protocol for the adjustment of insulin doses in diabetes
Organisation:
Aneurin Bevan University Health Board
Service area:
Adult Diabetes Service
Type of document:
Clinical protocol
Target population:
Adults with diabetes
Clinical setting:
Acute and community settings
Intended users:
Diabetes dietitians within the multidisciplinary team
Author:
Elaine Hibbert-Jones
Contributors:
Francesca Annan; Dorothy Debrah; Neera Agarwal; Kathryn John
Responsible committee:
Medicines Management
Geographical scope:
Wales
Insulin preparations:
Aneurin Bevan Drug Formulary
Exclusions:
Inpatients; pregnancy; paediatrics; insulin pump therapy without additional training
Date issued:
May 2018
Review date:
May 2021
Key topics:
Insulin dose adjustment; hypoglycaemia; hyperglycaemia; blood glucose monitoring; basal and bolus insulin; injection technique
Year:
2025
Region / City:
Lancashire (North, Central and East Lancashire), Blackpool, Blackburn with Darwen, South Cumbria
Topic:
Insulin safety
Document Type:
Prescribing Alert
Organisation:
LSC ICB Medicines Safety Committee
Author:
NHS England
Target Audience:
Healthcare professionals
Period of Action:
Ongoing
Approval Date:
06.08.2025
Modification Date:
06.08.2025
Year:
2024
Region / City:
Global
Topic:
Insulin treatment in children and adolescents with diabetes
Document Type:
Clinical Practice Consensus Guidelines
Institution:
ISPAD
Authors:
Eda Cengiz, Thomas Danne, Tariq Ahmad, Ahila Ayyavoo, David Beran, Ethel Codner, Sarah Ehtisham, Przemyslawa Jarosz-Chobot, Lucy N. W. Mungai, Sze May Ng, Megan Paterson, Leena Priyambada
Target Audience:
Healthcare professionals involved in pediatric diabetes care
Period of Effect:
2024 and ongoing
Approval Date:
2024
Date of Changes:
2024
Keywords:
Type 1 diabetes, insulin, children, adolescents, intensive insulin therapy, diabetes complications
Description:
Clinical guidelines for insulin therapy in pediatric diabetes, focusing on updated insulin treatment regimens, including bolus and basal insulins, as well as new insulin analogs and devices for therapy.
Note:
Year
Topic:
Health
Document Type:
Procedural Guideline
Organization:
Plano Independent School District
Target Audience:
School health staff, nurses
Year:
2015
Region / city:
Global
Topic:
Acute hyperkalemia treatment
Document type:
Research review
Organization / institution:
Not specified
Author:
Not specified
Target audience:
Healthcare professionals
Period of validity:
Not specified
Date of approval:
Not specified
Date of amendments:
Not specified
Conflict of Interests:
None
Clinical outcomes:
Potassium levels, ECG findings
Main intervention:
Intravenous calcium
Comparison:
No intervention, other interventions, placebo
Setting:
Adults
Background:
The acute treatment of hyperkalemia was reviewed in 2015.
Assessment:
Hyperkalemia is a common and life-threatening electrolyte imbalance.
Desirable effects:
Moderate effect of pharmacological intervention in mitigating hyperkalemia.
Undesirable effects:
Potential harm from calcium administration, especially in cardiac arrest patients.
Certainty of evidence:
Low certainty, based on limited observational data.
Values:
Primary outcome is ECG changes, with limited clinical relevant data.
Balance of effects:
Suggests against routine calcium use in cardiac arrest (weak recommendation).
Resources required:
Low cost of calcium.
Cost effectiveness:
No evidence of cost-effectiveness studies.
Equity:
No studies identified.
Acceptability:
Calcium has been recommended in international guidelines, but the new suggestion may face resistance.
Feasibility:
Feasible as a recommendation against routine use.
Context:
This document reviews evidence on the use of intravenous calcium for acute hyperkalemia treatment and recommends against its routine use in patients with hyperkalemia-induced cardiac arrest.
Population:
Paediatric patients in cardiac arrest suspected to be caused by hyperkalaemia
Intervention:
Insulin with glucose or salbutamol
Comparison:
No insulin with glucose and no salbutamol
Main outcomes:
Survival to discharge; Survival to discharge with favourable neurological outcome (PCPC 1–3 or no change from baseline); Survival to discharge with PCPC 1–2 or no change from baseline
Setting:
Any setting
Perspective:
Not specified
Conflict of interests:
None
Problem priority:
Varies
Desirable effects:
Small
Undesirable effects:
Trivial
Certainty of evidence:
No included studies
Values and preferences:
Probably no important uncertainty or variability
Balance of effects:
Probably favors the intervention
Resources required:
Varies
Certainty of evidence of required resources:
No included studies
Cost effectiveness:
No included studies
Equity impact:
Unknown
Acceptability:
Unknown
Feasibility:
Probably yes
Title:
Supplementary Information for Ethanol extract of Lentinus edodes exerted antioxidant activity in Caenorhabditis elegans by regulating insulin DAF-16 signaling pathway
Document Type:
Supplementary information
Section:
Materials and Methods
Research Topic:
Antioxidant activity and insulin DAF-16 signaling pathway
Biological Material:
Lentinus edodes
Model Organism:
Caenorhabditis elegans (N2)
Experimental Groups:
NFD, LEEE-L (0.1 mg/mL), LEEE-M (0.5 mg/mL), LEEE-H (1 mg/mL)
Extraction Method:
Ethanol extraction with ultrasonic treatment
In Vitro Assays:
DPPH, ABTS, hydroxyl radical scavenging assays
In Vivo Assays:
Heat stress assay, acute oxidative stress assay
Biochemical Indicators:
MDA, T-SOD, GSH-PX, CAT, ROS
Cell Analysis:
Apoptosis assay with acridine orange staining
Reagents and Kits:
Beyotime Biotechnology cell lysate; Jiancheng Bioengineering assay kits
Replication:
Three independent repeats per experiment
Geographical Reference:
Jinggangshan, China; Fuzhou, China; Shanghai, China; Nanjing, China
Storage Conditions:
-80°C freezer storage for extract
Note:
Year
Document Type:
Form
Target Audience:
Site Personnel, Principal Investigator
Year:
2015
Applies to:
Microsoft Office 2013, Microsoft SQL Server 2012 SP1 or higher, Microsoft SQL Server 2014
Type of document:
White paper
Author:
Kay Unkroth
Technical reviewers:
Alex Shteynberg, Andy Wu, Ariel Netz, Ashvini Sharma, Carolyn Rowe, Dave McPherson, Dave Wickert, David Hill, David Maguire, David Vugteveen, Denise Stendera, Diego Oppenheimer, Donny Rose, Dotan Elharrar, Frederic Gisbert, Guy Alroy, Haroon Ahmed, Haydn Richardson, Heidi Steen, Ileana Koller, Il-Sung Lee, Irina Gorbach, James Wu, Joanne Hendrickson, Joe Davies, John Hancock, John Sirmon, Kedar Dubhashi, Kevin Donovan, Mey Meenakshisundaram, Michiko Short, Mike Plumley, Nathaniel Scharer, Nick Simons, Nicolas Menigon, Parul Manek, Peter Brundrett, Prash Shirolkar, Reddy Duggempudi, Rob Lefferts, Robert Bruckner, Robert Skoglund, Sesha Mani, Sunil Gottumukkala, T.K. Anand, Uval Blumenfeld, V.B. Balayoghan, Venky Krishnan, Venky Veeraraghavan, Wayne Clark, Yair Tor, Craig Guyer
Publisher:
Microsoft Corporation
Copyright:
© 2014 Microsoft Corporation. All rights reserved.
Trademarks:
Microsoft, Microsoft Office 2013, Microsoft SharePoint Server, Microsoft SQL Server 2012, Microsoft SQL Server 2014, Microsoft Windows Azure
Scope:
Enterprise Microsoft BI solutions, including authentication, identity delegation, and multi-tier architectures
Target audience:
IT professionals, system architects, BI solution developers
Document type:
Technical reference
Year:
2015
Note:
Region / City
Topic:
Authentication, Azure AD, Kerberos, Active Directory
Document Type:
Technical Paper
Organ / Institution:
Microsoft Corporation
Target Audience:
IT Professionals, System Administrators, Network Administrators
Description:
A technical document detailing the implementation and troubleshooting of Kerberos Constrained Delegation (KCD) for Azure AD Application Proxy with Integrated Windows Authentication in enterprise environments.
Note:
Year
Topic:
Medical Licensing
Document Type:
Legal Regulation
Authority:
AS 08.64.100, AS 08.64.170, AS 08.64.336, AS 08.64.106, AS 08.64.326, AS 08.64.380, AS 08.64.107
Target Audience:
Healthcare Providers
Description:
Legal regulation on the delegation of routine medical duties by licensed healthcare providers.
Note:
Year
Document Type:
Clinical Research Delegation Log
Author:
Principal Investigator / Investigator of Record
Target Audience:
Research Staff