№ files_lp_3_process_9_61243
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Structured evidence-to-decision assessment evaluating the use of insulin with glucose or salbutamol in paediatric cardiac arrest suspected to be caused by hyperkalaemia, summarizing judgments on effects, evidence certainty, resource use, and implementation considerations.
Population:
Paediatric patients in cardiac arrest suspected to be caused by hyperkalaemia
Intervention:
Insulin with glucose or salbutamol
Comparison:
No insulin with glucose and no salbutamol
Main outcomes:
Survival to discharge; Survival to discharge with favourable neurological outcome (PCPC 1–3 or no change from baseline); Survival to discharge with PCPC 1–2 or no change from baseline
Setting:
Any setting
Perspective:
Not specified
Conflict of interests:
None
Problem priority:
Varies
Desirable effects:
Small
Undesirable effects:
Trivial
Certainty of evidence:
No included studies
Values and preferences:
Probably no important uncertainty or variability
Balance of effects:
Probably favors the intervention
Resources required:
Varies
Certainty of evidence of required resources:
No included studies
Cost effectiveness:
No included studies
Equity impact:
Unknown
Acceptability:
Unknown
Feasibility:
Probably yes
Price: 8 / 10 USD
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The product description is provided for reference. Actual content and formatting may differ slightly.
Country:
United Kingdom
Region:
England (not applicable to Wales, Northern Ireland and Scotland)
Issuing body:
Department of Health
Related legislation:
Children and Families Act 2014
Related guidance:
Supporting pupils at school with medical conditions
Subject:
Management of emergency salbutamol inhalers in schools
Document type:
Non-statutory guidance (draft for public consultation)
Legal status:
Non-statutory
Intended audience:
Governing bodies of maintained schools and proprietors of academies in England
Scope:
Supply, storage, use and disposal of emergency salbutamol inhalers in school settings
Consultation status:
Draft for public consultation
Effective date:
From [insert date] (upon commencement of relevant regulations)
Year:
2026
Region / City:
United Kingdom
Subject:
Healthcare, Environmental impact
Document type:
Patient information leaflet
Organization:
NHS
Medicine:
Salbutamol
New product:
Salamol®
Target audience:
Patients using salbutamol inhalers
Usage instructions:
Use as current salbutamol inhaler
Side effects:
Same as current salbutamol inhaler
Environmental benefit:
Reduced greenhouse gas emissions
Year:
2023
Region / city:
Australia
Topic:
Chronic hyperkalaemia, kidney disease, sodium zirconium cyclosilicate
Document Type:
Submission to PBAC
Agency / organization:
AstraZeneca Pty Ltd
Author:
Not specified
Target audience:
Medical practitioners, healthcare professionals
Period of validity:
Ongoing, based on PBAC recommendation and PBS listing
Approval date:
1 September 2023
Date of amendments:
Not specified
Year:
2021
Organization:
Canberra Health Services
Document Type:
Procedure
Scope:
Adult patients within Canberra Health Service
Target Audience:
Medical Officers, Registered Nurses, Registered Midwives, Students under supervision, Pharmacists
Purpose:
Guide staff on management of hyperkalaemia in adults
Attachments:
Flow Chart: Hyperkalaemia in Adults – Decision Making Tool
Related Policies:
Informed Consent (Clinical), Medication Handling Procedures, Infection Prevention and Control, Patient Identification – Pathology Specimen Labelling, Access for Renal Replacement Therapy, Vital Signs and Early Warning Scores
Legislation:
Health Records (Privacy and Access) Act 1997, Human Rights Act 2004, Work Health and Safety Act 2011, Medicines, Poisons and Therapeutic Goods Act 2008, Therapeutic Goods Act 1989, Australian Charter of Healthcare Rights
References:
Australian Injectable Drugs Handbook, 8th edition, 2021
Year:
2020
Region / city:
Australia
Theme:
Health, pharmaceutical, clinical treatment
Document type:
Submission for drug listing
Organization / institution:
PBAC (Pharmaceutical Benefits Advisory Committee)
Author:
Vifor Pharma Pty Limited
Target audience:
Healthcare professionals, regulatory bodies
Period of validity:
Ongoing
Approval date:
12 December 2017
Amendment date:
November 2020
Version:
1.0
Circulated date:
January 2024
Review date:
July 2024
Scope:
Children and young people with Type 1 diabetes (CYP with T1DM)
Guideline reference:
NICE NG18 (2022)
Type:
Implementation document
Region:
London
Target audience:
Paediatric diabetes teams, healthcare professionals, CYP with T1DM and their families
Components:
Written pathway, implementation flowchart, accompanying device list
Device focus:
Continuous glucose monitoring (CGM)
Purpose:
Support implementation of NG18 and guide device choice
Year:
2026
Region / City:
Canberra, Australia
Subject:
Blood glucose and ketone point-of-care testing
Document Type:
Procedure
Organization:
Canberra Health Services (CHS)
Intended Users:
Medical Officers, Nurses and Midwives, Allied Health Professionals, Students under supervision
Equipment:
Nova Statstrip XpressTM meter
Scope:
Inpatient facilities and community services of CHS Network
Compliance:
Internal Quality Control, External Quality Assurance Programme (EQAP)
Safety Measures:
Standard precautions and infection control procedures
Record Keeping:
Quality Control Logbook, EQAP reports retention
Year:
2023
Region / city:
United States, Abu Dhabi, Cambridge, Riyadh, Detroit, Brooklyn, Los Angeles
Theme:
Health, Diabetes, Mortality, Cardiovascular Disease
Document Type:
Research Article
Organization / Institution:
Drexel University, NYU Lutheran Medical Center, University of California San Francisco, University of Cambridge, King Faisal Specialist Hospital, Wayne State University
Author:
Sunil E. Saith, MD, Andrew Kohut, MD, MPH, Jun Tang, Ph.D, Greg Irving, MBBS, Shamma A. Al Memari, MBBS, Afra D. Al Dhaheri, MBBS, Fatimah S. Alhamlan, Ph.D, Mahdi Shkoukani, MD
Target Audience:
Medical researchers, healthcare professionals, clinicians
Period of Effect:
N/A
Approval Date:
N/A
Date of Changes:
N/A
Abstract:
To assess if high-normal random blood glucose (RBG) levels correlate with higher all-cause mortality risk compared to normal RBG levels.
Introduction:
Investigates the relationship between high-normal blood glucose levels and increased mortality risk.
Year:
2024
Region / City:
United States
Topic:
Health, Diabetes Management
Document Type:
Addendum, Medical Form
Organization / Institution:
Diabetes Resource Nurses of Colorado, Inc.
Author:
Diabetes Resource Nurses of Colorado, Inc.
Target Audience:
School Nurses, Parents, Healthcare Providers
Approval Date:
September 2024
Date of Changes:
September 2024
Note:
Year
Region / City:
North Central London
Topic:
Continuous Glucose Monitoring (CGM)
Document Type:
Information Document
Organization:
NHS
Target Audience:
General Practices in North Central London
Year:
2023
Region / city:
North East London
Topic:
Healthcare, Diabetes, Continuous Glucose Monitoring
Document Type:
Medical Guidance
Organization:
Barts Health NHS Trust, Homerton Healthcare NHS Foundation Trust, Barking, Havering and Redbridge University Hospitals NHS Trust
Author:
Specialist diabetes teams
Target Audience:
Healthcare professionals, primary care physicians
Period of validity:
Not specified
Approval Date:
Not specified
Date of changes:
August 2023
Note:
Context description
Year:
2023
Region / City:
Not specified
Topic:
Tumor Metabolism, Glycolysis, Kinetic Modeling
Document Type:
Research Paper
Institution / Organization:
Not specified
Author:
JHGM van Beek
Target Audience:
Researchers in biochemistry and oncology
Period of Validity:
Not specified
Approval Date:
Not specified
Modification Date:
Not specified
Title:
Supplementary Material 1: KAP Questionnaire for Glucose Management
Document type:
Questionnaire
Subject:
Glucose management in critically ill patients
Structure:
Knowledge dimension; Attitude dimension; Practice dimension
Target population:
ICU nurses
Clinical focus:
Glycemic control, insulin therapy, hypoglycemia and hyperglycemia management
Measurement units:
mmol/L; U/ml
Setting:
Intensive care unit
Reference:
Specialist service referral to GP
Document type:
Clinical recommendation letter
Subject:
Prescription of isCGM or rtCGM device
Related conditions:
Type 1 diabetes; Type 2 diabetes
Guidance referenced:
NICE NG17; NICE NG18; NICE NG28
Regional policy:
Cheshire and Merseyside Area Prescribing Group recommendation
Device category:
Intermittently scanned continuous glucose monitoring (isCGM); Real time continuous glucose monitoring (rtCGM)
Intended recipient:
General Practitioner
Patient status:
Counselled and informed regarding device use and access
Clinical context:
Green status for adults; Amber Recommended for children with type 1 diabetes and eligible people with type 2 diabetes
Year:
2023
Region / City:
Fukuoka, Japan
Topic:
Medical / Health
Document Type:
Research Article
Author:
Hitomi Miyazaki, Masumi Nagae, Hiroshi Uchida, Kuniyoshi Shimizu
Target Audience:
Medical professionals, researchers
Approval Date:
December 8th, 2023
Study Participants:
18 healthy adult men and women
Ethics Approval:
Yes
Conflicts of Interest:
None
Publication Fee:
$1,595.00
Journal:
Functional Foods in Health and Disease
Co-author Contact:
Masumi Nagae, Hiroshi Uchida, Kuniyoshi Shimizu
Peer Reviewers:
Masaki Taga, Hiroaki Masuzaki, Toshio Hosaka, Mei Hui Liu, Anne Nilsson
Organization:
POCT Pathology Department
Role:
POCT Coordinator
Contact Telephone:
07500050655
Contact Email:
[email protected]
Subject:
Glucose and Ketone Quality Control Procedure
Device:
FPP Meter
Testing Types:
Glucose Testing, Ketone Testing
Procedure Type:
Quality Control Instruction
Intended Users:
Clinical Staff Operating FPP Meter
Document Purpose:
Operational Guidance
Year:
2026
Region:
Laboratory Study
Subject:
Blood Glucose Measurement
Document Type:
Research Data Report
Institution:
University or Research Laboratory
Author:
Not specified
Target Audience:
Biomedical researchers
Study Period:
Post-induction observation
Date of Data Collection:
Not specified
Test Methods:
Descriptive statistics, Normality tests, ANOVA, Kruskal-Wallis, Post-hoc LSD
Variables Measured:
GDP_Pre, GDP_Post, VAR00001, VAR00005
Experimental Groups:
K-, K+, P1, P2
Sample Size:
15 subjects across 4 groups
Statistical Software:
Not specified
Data Distribution Analysis:
Lilliefors correction, Shapiro-Wilk test
Variance Homogeneity Tests:
Levene, Robust equality tests
Significance Threshold:
0.05
Analysis Focus:
Differences in blood glucose levels between experimental groups
Year:
2016
Region / Institution:
Hull & East Yorkshire NHS Hospitals Trust, UK
Topic:
Diabetes management, glucose monitoring
Document type:
Clinical guidance summary
Author:
Dr Jane Patmore
Target audience:
Healthcare professionals, patients with Type 1 diabetes
Guideline source:
NICE NG17
Device discussed:
Freestyle Libre flash glucose monitoring system
Patient criteria:
Severe hypoglycaemia, hypoglycaemia unawareness, frequent asymptomatic hypoglycaemia, extreme fear of hypoglycaemia, persistent hyperglycaemia, recurrent DKA
Study references:
JDRF CGM study, ABCD position statement, American Diabetes Association 2016 abstract
Data presentation:
Ambulatory Glucose Profile (AGP)
Implementation setting:
Clinical and home use for patient monitoring
Outcome focus:
Reduction of hypoglycaemia, improved glycaemic control, hospital admission reduction
Year:
2019-2022
Region / City:
Israel
Topic:
Continuous Glucose Monitoring, Non-Diabetic Population
Document Type:
Research Article
Institution:
Weizmann Institute of Science, Tel Aviv University, Rabin Medical Center, Pheno.AI
Authors:
Ayya Keshet, Smadar Shilo, Anastasia Godneva, Yeela Talmor-Barkan, Yaron Aviv, Eran Segal, Hagai Rossman
Target Audience:
Researchers, Clinicians
Study Population:
7,104 non-diabetic adults, aged 40-70, 45.7% male, 54.3% female
Methodology:
Continuous Glucose Monitoring, blood tests, DXA scans, food intake logging, sleep monitoring
Key Measurements:
Mean blood glucose, glucose variability, clinical measures related to cardiovascular health, nutrition, and sleep
Lead Contact:
Dr. Hagai Rossman
Corresponding Author:
Prof. Eran Segal
Purpose:
Establish reference values for CGM-derived metrics in a healthy population
Subject:
Biology
Topic:
Homeostasis and blood glucose regulation
Type of document:
Educational worksheet
Educational level:
Secondary school biology
Concepts covered:
Homeostasis, insulin, blood glucose concentration, type 1 diabetes
Activities included:
Graph interpretation, short explanations, multiple-choice questions, labeling tasks
Physiological processes:
Regulation of blood glucose by insulin and endocrine system
Medical condition discussed:
Type 1 diabetes
Assessment format:
Student questions and tasks