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Quantitative synthesis of randomized controlled trials evaluating the effects of various exercise modalities on verbal and spatial memory performance in patients diagnosed with depression.
Year:
2026
Region:
International
Topic:
Exercise interventions and memory outcomes in depression
Document type:
Systematic review and meta-analysis
Authors:
Halappa, Lavretsky, Khatri, Imboden, Hoffman, Krogh, Oertel-Knochel, Bushert, Zheng, Sharma, Chen, Zhang
Target population:
Clinically diagnosed patients with depression
Study design:
Randomized controlled trials
Cognitive domains assessed:
Verbal memory, spatial memory
Intervention types:
Yoga, aerobic exercise, strength training, TMS
Duration of interventions:
4–16 weeks
Outcome measures:
RAVLT, DSTF, DSTB, WMS, BSRT, RCFT, VLMT
Methodological approach:
Leave-one-out meta-analysis, RoB 2.0 risk assessment, GRADE certainty rating
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Year:
2021
Region/Institution:
University of Wisconsin, University of Minnesota, University of Connecticut, University of Maryland, USA
Document Type:
Supplementary material
Authors:
Guanmin Liu, Na Zhang, Jia Yuan Teoh, Christine Egan, Thomas A. Zeffiro, Richard J. Davidson, Karina Quevedo
Corresponding Author:
Karina Quevedo, [email protected]
Target Population:
Depressed adolescents and healthy controls
Study Method:
fMRI, Emotional Self-Other Morph-Query (ESOM-Q) task, behavioral measures
Sample Size:
81 depressed youth, 37 healthy controls
Variables Measured:
Depression severity, self-compassion, response time, accuracy, fMRI activity
Demographics:
Age, sex, race/ethnicity, puberty stage, household income, parental marital status
Medication Use:
Antidepressant, antipsychotic, mood stabilizer, stimulant, anxiolytic
Document type:
Supplementary online content
Related study:
Personalized Prognostic Prediction of Treatment Outcome for Depressed Patients in a Naturalistic Psychiatric Hospital Setting: A Comparison of Machine Learning Approaches
Setting:
Naturalistic psychiatric hospital setting
Treatment providers:
Psychologists, postdoctoral fellows, clinical psychology interns, psychology practicum students, mental health counselors
Treatment format:
Group treatment
Adherence assessment:
Bi-annual fidelity assessments via live observation and checklists
Adherence rates:
89%–95%
Population:
Depressed patients, including individuals with MDD and comorbid diagnoses
Predictor variables:
Clinical measures, demographic characteristics, MDD history, comorbid diagnoses, treatment history, psychiatric medication use, physical health variables
Outcome measures:
PHQ-9, GAD-7
Statistical methods:
Random Forest imputation (missForest in R), Elastic Net Regression, Lasso, Ridge, Random Forest, Support Vector Machines, Bayesian additive trees, Super Learner, adaptive splines
Validation approach:
10-fold cross-validation and hold-out sample testing
Performance metrics:
Mean Absolute Error (MAE), Mean Squared Error (MSE), R2, squared correlation (r2) with 95% confidence intervals
Year:
1940s
Region / City:
New Orleans
Topic:
Theatre, Southern Gothic, Symbolism, Social Change, American Dream
Document type:
Analytical Essay
Institution:
N/A
Author:
N/A
Target Audience:
Theatre students, Scholars of American Literature
Period of validity:
N/A
Approval date:
N/A
Date of changes:
N/A
Note:
Contextual description
Word Count:
4480 words
Version:
1
Clinical Trial Registry:
An 8-week, open-label study to evaluate the effect of sertraline on the polysomnographic results of depressive patients with insomnia
Registry identifier:
NCT01032434
Note:
Abbreviations
5-HT:
serotonin
AASM-2007:
American Academy of Sleep Medicine 2007 version
AHI:
apnea-hypopnea index
AI:
arousal index
ANOVA:
one-way analysis of variance
BMI:
body mass index
CT:
Computed tomography
DA:
dopaminergic
DSM-IV:
diagnostic and statistical manual of mental disorders, fourth edition
ECG:
Electrocardiograph
EMG:
electromyogram
EOG:
electrooculography
ESS:
Epworth sleepiness scale
HRSD:
Hamilton rating scale for depression
MSLT:
multiple sleep latency test
OSA:
obstructive sleep apnea
OCD:
obsessive-compulsive disorder
PD:
Parkinson’s disease
PLMI:
periodic limb movement index
PLMS:
periodic limb movement during sleep
PSG:
polysomnography
PSQI:
Pittsburgh sleep quality index
REM:
rapid eye movement
RSWA:
REM sleep without atonia
RLS:
restless legs syndrome
SCID-2:
the second version of the Structured Clinical Interview for DSM-IV Axis I Disorders
SE:
Sleep efficiency
SL:
Sleep latency
SSRI:
selective serotonin reuptake inhibitors
TESS-S:
treatment emergent symptom scale-severity
TESS-T:
treatment emergent symptom scale-treatment
TRT:
total recording time
TST:
total sleep time
vPSG:
video-polysomnography
WASO:
wake after sleep onset
Year:
2010
Region / city:
Global
Subject:
Sleep disorders, depression, REM sleep without atonia
Document type:
Clinical trial study
Institution:
Clinical Trials.gov
Author:
Not specified
Target audience:
Medical professionals, researchers in sleep disorders
Period of action:
8 weeks
Approval date:
Not specified
Modification date:
Not specified
Year:
2025
Date Issued:
Aug-2025
Document Type:
Urgent Field Safety Notice
Reference Number:
ACHC 25-07.A.OUS
Product:
Atellica CH Urinary/Cerebrospinal Fluid Protein Assay (UCFP)
Test Code:
UCFP
Siemens Material Number:
11097543
Unique Device Identification:
00630414279206
Lot Number:
All lots
Affected Systems:
Atellica CH Analyzer; Atellica CI Analyzer
Manufacturer:
Siemens Healthcare Diagnostics Inc.
Organization:
Siemens Healthineers
Single Registration Number (SRN):
US-MF-000016560
Issue:
Potential for falsely depressed patient, QC, and calibration results in initial replicate(s) of a freshly punctured reagent well stored onboard
Maximum Observed Negative Bias:
-19.0 mg/dL (-190 mg/L)
Sample Types:
Urine; Cerebrospinal Fluid (CSF)
Required Actions:
Update QC settings, enable QC on Pack Change, enable Patient QC Flagging, repeat testing of flagged results, change well status if QC fails, complete and return Field Correction Effectiveness Check Form within 30 days
Appendix:
Detailed customer instructions for QC configuration and well status changes
Copyright:
© Siemens Healthcare Diagnostics Inc. 2024
Year:
2025
Region / City:
West Glamorgan
Subject:
Integrated Discharge Strategy, Hospital Discharge, Patient Care
Document Type:
Report
Institution:
West Glamorgan Regional Partnership Board
Author:
Emily Warren, Helen St John
Target Audience:
Health and Social Care Professionals, Policy Makers
Period of Action:
May 2024 - March 2025
Approval Date:
28 January 2025
Date of Amendments:
Not specified
Context:
A report detailing the progress of the Integrated Discharge Strategy (IDS), which aims to improve discharge planning and reduce patient delays at hospitals.
Live Attenuated Vaccines: Avoid Use In Those Who Are Clinically Immunosuppressed, Including Neonates
Year:
2016
Region / City:
Wales
Topic:
Vaccination, Immunosuppression
Document Type:
Medical/Health Advisory
Organization:
NHS Wales
Author:
Dr Chris Jones
Target Audience:
Healthcare professionals, General practitioners, Paediatricians, Oncologists, Rheumatologists, Immunologists, Nurses, Pharmacists, Medical Directors
Period of Validity:
Not specified
Approval Date:
4 May 2016
Modification Date:
Not specified
Contextual Description:
Medical advisory document warning healthcare professionals about the risks of live attenuated vaccines for immunosuppressed individuals, especially neonates and elderly patients.
Year:
2023
Region / City:
Temple University Hospital, USA
Subject:
EEG, Neuroscience, Medical Research
Document Type:
Research Article
Institution:
Temple University
Author:
Multiple contributors
Target Audience:
Researchers, Medical Professionals
Period of Data Collection:
14 years
Approval Date:
Not specified
Date of Latest Update:
Not specified
Year:
2023
Region / City:
Southern Health
Topic:
Medical guidelines for opioid patch use and syringe driver medication administration
Document type:
Clinical Protocol
Organization:
HHFT (Southern Health NHS Foundation Trust)
Author:
Southern Health NHS Foundation Trust
Target Audience:
Healthcare professionals involved in palliative care and medication administration
Period of validity:
April 2023
Date of approval:
April 2023
Date of changes:
April 2023
Year:
2026
Region / city:
United States
Topic:
Health assessment and risk management for potential infectious disease exposure
Document type:
Risk assessment form
Organization:
Centers for Disease Control and Prevention (CDC)
Author:
Centers for Disease Control and Prevention (CDC)
Target audience:
Healthcare providers, public health officials
Period of validity:
Ongoing
Approval date:
2026
Date of changes:
N/A
Description:
A health risk assessment form used by CDC to assess potential exposure to [SAMPLE VHF] and guide public health responses at points of entry.
Year:
2023
Region / city:
United Kingdom
Topic:
Healthcare, Infection Control
Document Type:
Standards
Organization:
National Health Service (NHS)
Author:
NHS Infection Prevention and Control (IP&C) Committee
Target Audience:
Healthcare Providers, Clinical Staff, Infection Control Teams
Period of validity:
Ongoing
Approval Date:
2023-01-01
Amendment Date:
2023-01-01
Year:
2023
Region / City:
Australia
Subject:
Healthcare, Medicare Benefits Schedule
Document Type:
Factsheet
Organization:
Department of Health and Aged Care
Author:
Department of Health and Aged Care
Target Audience:
Healthcare providers, referrers, private health insurance stakeholders
Effective Date:
1 November 2022
Amendment Date:
1 March 2023
Sample size:
10378 patients
Medical condition:
Prostate cancer
Subgroups:
Clinically significant prostate cancer (csPCa), Insignificant prostate cancer (Ins-PCa), All prostate cancer (PCa)
Variables analyzed:
Age, PSA level, Prostate volume (PV), PSA density (PSAD), PI-RADS score
Age categories:
<50; 50–60; 60–70; 70–80; ≥80 years
PSA categories:
<10; 10–20; 20–50; 50–100; ≥100 ng/mL; Unknown
Prostate volume categories:
<30; 30–40; 40–60; ≥60 ml; Unknown
PSA density categories:
<0.1; 0.1–0.15; 0.15–0.2; ≥0.2; Unknown
Imaging classification system:
PI-RADS (Prostate Imaging-Reporting and Data System)
Data type:
Quantitative clinical characteristics with counts and percentages
Medical field:
Urology / Oncology
Document type:
Statistical table of clinical study data
Year:
2021-2022
Region / city:
Abuja, Nigeria
Theme:
Traumatic brain injury, Clinical research
Document type:
Research article
Institution:
National Hospital Abuja
Author:
Not specified
Target audience:
Medical professionals, researchers
Period of validity:
N/A
Approval date:
N/A
Date of amendments:
N/A
Type of document:
Systematic review and meta-analysis
Authors:
Lydia Neuberger; Philip Braude; Kayleigh Weeks; Peter Braude; Ruth Halliday; Kathryn McCarthy; Ben Carter
Institutions:
North Bristol NHS Trust, Southmead Hospital, Bristol, UK; King’s College London, UK; University of Nottingham, UK
Corresponding author:
Philip Braude
Study population:
Adults aged 60 years and older
Clinical focus:
Abdominal stoma formation in older people
Outcomes assessed:
Physical function; quality of life; functional independence; stoma independence
Databases searched:
CINAHL; EMBASE; EMCARE; PubMed
Search date:
13 September 2021
Protocol registration:
PROSPERO
Number of included studies:
25
Number of participants:
6,972
Abstract word count:
248
Manuscript word count:
3,498
Number of figures:
3
Number of tables:
0
Keywords:
Stoma; Physical Functioning; Quality of Life; Functional Independence; Self-efficacy
Note:
Year
Note:
Year
Year:
2023
Region / City:
London, Norwich, Liverpool, UK
Topic:
Medical Research
Document Type:
Systematic Review with Meta-Analysis
Author:
Tristan D Boam, Melissa Gabriel, Rajeev Shukla, Paul D Losty
Target Audience:
Healthcare professionals, researchers in paediatric oncology
Period of Effect:
1990-2020
Approval Date:
Not specified
Date of Changes:
Not specified
Year:
2017
Region / city:
United States, international
Topic:
Adolescent sexual health, school-based interventions
Document type:
Systematic review, meta-analysis
Organization:
ETR, London School of Hygiene and Tropical Medicine, New York City Department of Health and Mental Hygiene
Author:
Amy J Peterson, Melissa Donzec, Elizabeth Allend, Chris Bonell
Target audience:
Researchers, public health professionals
Period of validity:
N/A
Approval date:
N/A
Date of changes:
N/A