This document is a clinical trial study on the effect of sertraline on REM sleep without atonia in depressed patients.
Word Count:
4480 words
Version:
1
Clinical Trial Registry:
An 8-week, open-label study to evaluate the effect of sertraline on the polysomnographic results of depressive patients with insomnia
Registry identifier:
NCT01032434
Note:
Abbreviations
5-HT:
serotonin
AASM-2007:
American Academy of Sleep Medicine 2007 version
AHI:
apnea-hypopnea index
AI:
arousal index
ANOVA:
one-way analysis of variance
BMI:
body mass index
CT:
Computed tomography
DA:
dopaminergic
DSM-IV:
diagnostic and statistical manual of mental disorders, fourth edition
ECG:
Electrocardiograph
EMG:
electromyogram
EOG:
electrooculography
ESS:
Epworth sleepiness scale
HRSD:
Hamilton rating scale for depression
MSLT:
multiple sleep latency test
OSA:
obstructive sleep apnea
OCD:
obsessive-compulsive disorder
PD:
Parkinson’s disease
PLMI:
periodic limb movement index
PLMS:
periodic limb movement during sleep
PSG:
polysomnography
PSQI:
Pittsburgh sleep quality index
REM:
rapid eye movement
RSWA:
REM sleep without atonia
RLS:
restless legs syndrome
SCID-2:
the second version of the Structured Clinical Interview for DSM-IV Axis I Disorders
SE:
Sleep efficiency
SL:
Sleep latency
SSRI:
selective serotonin reuptake inhibitors
TESS-S:
treatment emergent symptom scale-severity
TESS-T:
treatment emergent symptom scale-treatment
TRT:
total recording time
TST:
total sleep time
vPSG:
video-polysomnography
WASO:
wake after sleep onset
Year:
2010
Region / city:
Global
Subject:
Sleep disorders, depression, REM sleep without atonia
Document type:
Clinical trial study
Institution:
Clinical Trials.gov
Author:
Not specified
Target audience:
Medical professionals, researchers in sleep disorders
Period of action:
8 weeks
Approval date:
Not specified
Modification date:
Not specified
