№ files_lp_4_process_3_107590
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Systematic review and meta-analysis supplemental tables and figures summarizing study characteristics, bias assessments, and analyses of vitamin D levels in relation to neoadjuvant chemotherapy response in breast cancer.
Year:
2026
Region / City:
International / Multicenter
Subject:
Breast cancer, Vitamin D, Neoadjuvant chemotherapy
Document type:
Supplemental material for research article
Institution / Organization:
Academic research institutions
Authors:
Not specified
Study population:
Patients with breast cancer undergoing neoadjuvant chemotherapy
Data sources:
Medline, Embase, Cochrane Library, Web of Science
Methods:
Literature search, data extraction, quality assessment, subgroup and sensitivity analyses, meta-analysis
Outcome measures:
Overall pathological response, pathological complete response (pCR), event-free survival (EFS)
Period covered:
Not explicitly stated, studies pooled from multiple cohorts
Supplementary content:
Tables of search strategy, data extraction, baseline characteristics, quality assessment; figures for bias, funnel plots, subgroup and sensitivity analyses, forest plots
Price: 8 / 10 USD
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Year:
2023
Region / City:
London, Norwich, Liverpool, UK
Topic:
Medical Research
Document Type:
Systematic Review with Meta-Analysis
Author:
Tristan D Boam, Melissa Gabriel, Rajeev Shukla, Paul D Losty
Target Audience:
Healthcare professionals, researchers in paediatric oncology
Period of Effect:
1990-2020
Approval Date:
Not specified
Date of Changes:
Not specified
Year:
2023
Region / City:
Southampton, UK
Topic:
Oesophago-gastric cancer, neoadjuvant therapy, cardiopulmonary exercise testing
Document Type:
Research Article
Institution:
University of Southampton, Southampton NIHR Biomedical Research Centre
Author:
Malcolm A West, William CA Baker, Saqib Rahman, Alicia Munro, Sandy Jack, Michael PW Grocott, Timothy J Underwood, Denny ZH Levett
Target Audience:
Medical professionals, oncologists, researchers
Period of Effectiveness:
Not specified
Approval Date:
Not specified
Date of Modifications:
Not specified
Year:
2023
Study type:
Clinical trial, Phase II
Disease focus:
Hormone receptor-positive, HER2-negative breast cancer
Intervention:
Letrozole plus Alpelisib
Cohorts:
PIK3CA-mutant, PIK3CA-wild-type
Sample size:
83 patients
Authors:
Ingrid A. Mayer, Aleix Prat, Daniel Egle, et al.
Endpoints:
Objective response rate (ORR), pathological complete response (pCR), safety and adverse events
Methods:
PIK3CA mutation testing via cobas® PIK3CA Mutation Test and Oncomine™ Focus Assay
Data collection period:
Baseline through ≥24 weeks of treatment
Primary outcomes:
Tumor response rates, adverse event frequency and severity
Safety outcomes:
Rash, gastrointestinal toxicities, hyperglycemia, liver enzyme elevations, hematologic events
Target population:
Adults with hormone receptor-positive, HER2-negative breast cancer eligible for neoadjuvant therapy
Regulatory status:
Approved investigational study protocol
Context:
Clinical study report presenting supplementary methods, patient characteristics, treatment exposure, response rates, and adverse events for a Phase II randomized trial of letrozole plus alpelisib in hormone receptor-positive, HER2-negative breast cancer patients.
IUP Number:
006
40 CFR Category:
433.17
Permittee:
Will Plateit Company
Facility Location:
1234 Industry Drive, Typicalville, NC 27666
Receiving POTW Name:
Typicalville WWTP
Receiving POTW NPDES #:
NC0012345
IUP Effective Date:
January 1, 2009
IUP Expiration Date:
December 31, 2013
Date Signed:
November 15, 2008
Control Authority:
Town of Typicalville
Note:
Description
Document type:
Annual compliance report
Regulatory program:
National Pollutant Discharge Elimination System (NPDES)
Sector:
Wastewater treatment
Subject area:
Industrial pretreatment
Responsible authority:
Minnesota Pollution Control Agency
Applicable entities:
Publicly Owned Treatment Works
Reporting frequency:
Annual
Reporting period:
Calendar year
Geographic scope:
Minnesota
Submission method:
Email submission to regulatory authority
Required attachments:
SIU information form; SIU monitoring forms
Certification requirement:
Authorized official signature under penalty of law
Legal basis:
Minnesota Rules 7049.0630
Note:
Year
Organization:
Metro Water Recovery
Year:
2019
Region / City:
Wyoming Valley, PA
Topic:
Mercury discharge regulations
Document type:
Compliance report
Institution:
Wyoming Valley Sanitary Authority
Author:
Wyoming Valley Sanitary Authority
Target audience:
Dental facility operators
Period of validity:
Indefinite, until ownership transfer
Date of approval:
N/A
Date of modifications:
N/A
Year:
2025
Region / City:
Global
Topic:
Microalgae cultivation, wastewater treatment, biomass production
Document Type:
Research Article
Organization / Institution:
Academic/Research Institution
Author:
Oslan et al.
Target Audience:
Researchers, environmental scientists, biotechnologists
Period of Validity:
2025
Approval Date:
2025
Date of Modifications:
Not specified
Year:
2025
Region / City:
United States
Topic:
Transportation Research
Document Type:
Progress Report
Agency / Organization:
Federal Highway Administration (FHWA)
Author:
Jim Austrich
Target Audience:
Transportation Agencies, Research Organizations
Period of Validity:
4/13/2022 – 4/12/2027
Approval Date:
4/13/2022
Date of Changes:
N/A
Year:
2025
Region / City:
Kabul
Theme:
Sub-regional study, pooled fund
Document Type:
Invitation to Tender
Organization / Institution:
Norwegian Refugee Council (NRC)
Author:
Norwegian Refugee Council (NRC)
Target Audience:
Bidders for the tender
Validity Period:
Until 28th December 2025
Approval Date:
4th December 2025
Amendment Date:
Not specified
Year:
2025
Region / City:
Nationwide
Topic:
Traffic Control Devices, Transportation Research
Document Type:
Progress Report
Agency / Institution:
FHWA
Author:
Laura Mero, FHWA
Target Audience:
State, local, and regional transportation agencies
Period of Validity:
Ongoing
Approval Date:
Not specified
Date of Changes:
Not specified
Year:
2023
Region / City:
USA
Topic:
Transportation, Safety Service Patrol
Document Type:
Progress Report
Agency/Institution:
FHWA
Author:
Jim Austrich
Target Audience:
Transportation Agencies, Research Entities
Effective Period:
2022-2027
Approval Date:
12/07/2021
Modification Date:
N/A
Year:
2024
Region / City:
Missouri
Theme:
Public-Private Partnership, Transportation Data
Document Type:
Progress Report
Organization / Institution:
Missouri Department of Transportation
Author:
Jen Harper
Target Audience:
Transportation professionals, OEMs, government agencies
Effective Period:
December 1, 2024 – November 30, 2028
Approval Date:
N/A
Amendment Date:
N/A
Year:
2023
Region / City:
N/A
Topic:
403(b) plans, multiple employer plans (MEP), pooled employer plans (PEP), IRS regulations
Document Type:
Legal Amendment
Organization / Institution:
FIS
Author:
FIS
Target Audience:
Employers, plan administrators
Effective Date:
2025
Date of Approval:
N/A
Date of Changes:
N/A
Year:
2019
Region / City:
Utah
Topic:
Transportation Research
Document Type:
Progress Report
Agency:
Utah Department of Transportation
Author:
Scott Nussbaum
Target Audience:
Project managers, researchers, transportation professionals
Period of Activity:
2016-2021
Approval Date:
Not specified
Modification Date:
Not specified
Year:
2024
Region / City:
Virginia
Subject:
Transportation research, Pavement management, Structural data
Document Type:
Progress report
Agency / Institution:
Virginia Department of Transportation (VDOT)
Author:
Brian Diefenderfer
Target Audience:
Project Managers, Transportation Researchers, Agency Stakeholders
Period of Validity:
January 1, 2024 – December 31, 2024
Approval Date:
Not specified
Amendment Date:
Not specified