№ files_lp_4_process_2_73546
Supplementary figure caption from a pharmacokinetic study reporting LC-MS/MS measurements of total ADC, total monoclonal antibody, and free MMAE concentrations in blood after a single 6.0 mg/kg dose of MYTX-011 in cynomolgus monkeys.
Document Type: Supplementary scientific figure description
Study Subject: Cynomolgus monkeys
Sample Size: n=3 per group
Test Article: MYTX-011
Dose: 6.0 mg/kg single dose
Analytes Measured: Total ADC, total mAb, free MMAE
Biological Matrix: Blood
Analytical Method: LC-MS/MS assays
Research Context: Pharmacokinetic measurement following administration of an antibody–drug conjugate
Key Observation: Similar levels of total mAb and total ADC indicating high stability of site-specific conjugation
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