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Scholarly medical review examining the composition and functions of human microbiota and its relationship with kidney diseases and outcomes after renal transplantation, including dysbiosis, immune interactions, and potential therapeutic approaches.
Journal:
World Journal of Transplantation
Article Type:
Review
Title:
Microbiota, renal disease and renal transplantation
Authors:
Maurizio Salvadori; Aris Tsalouchos
Corresponding Author:
Maurizio Salvadori
Author Affiliation:
Department of Transplantation Renal Unit, Careggi University Hospital, Florence, Italy
Note:
Author Affiliation
Nephrology and Dialysis Unit, Saints Cosmas and Damian Hospital, Pescia, Italy
Publisher:
Baishideng Publishing Group Inc.
Year:
2021
Volume:
11
Issue:
3
Pages:
16–36
DOI:
10.5500/wjt.v11.i3.16
URL:
https://www.wjgnet.com/2220-3230/full/v11/i3/16.htm
Received:
December 4, 2020
Revised:
January 6, 2021
Accepted:
February 12, 2021
Published Online:
March 18, 2021
Academic Field:
Nephrology; Transplantation Medicine; Microbiology
Keywords:
Gut commensals; Microbioma; Microbiota; Renal disease; Renal transplantation; Transplant outcomes
Institutions:
Careggi University Hospital; Saints Cosmas and Damian Hospital
Country:
Italy
Language:
English
Copyright:
© The Author(s) 2021. Published by Baishideng Publishing Group Inc.
Price: 8 / 10 USD
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Year:
2023
Region / City:
Kenya
Topic:
Vaginal microbiota, gestational age, preterm birth
Document Type:
Research study
Institution:
University of Nairobi, University of Washington, Kenyatta National Hospital, Coast General Teaching and Referral Hospital, Women’s Healthcare Associates, Fred Hutchinson Cancer Centre, PathCare Laboratories
Author:
R. Scott McClelland, Jackson Nyangaresi, Erica M Lokken, Sujatha Srinivasan, John Kinuthia, Barbra A Richardson, Hudson Alumera, Sophia M R Lannon, Shahid Hussein, Tina Fiedler, Anne Pulei, Matthew Munch, Arthur Kemoli, Sean Proll, Kishorchandra N Mandaliya, Grace John-Stewart, Walter Jaoko, David N Fredricks
Target Audience:
Researchers, healthcare professionals
Period of validity:
April 2017 – December 2020
Date of approval:
Not stated
Date of changes:
Not stated
Document type:
Supplementary material
Study subject:
Effects of chronic blue and white LED lighting on gut microbiota and cholesterol metabolism in mice
Experimental duration:
44 weeks
Biological focus:
Gut microbiota composition and lipid metabolism
Key methods:
LEfSe analysis; LDA effect size; heatmap analysis; one-way ANOVA; correlation analysis; Venn diagram; BaseSpace (Illumina) identification
Main variables:
LED wavelength; irradiance level; serum cholesterol level; alpha diversity; bile acid biosynthesis
Organisms studied:
Mice; Lactobacillus spp.
Statistical threshold:
p value < 0.05
Figures included:
S1; S2; S3; S4; S5; S6
Analytical scope:
Taxonomic classification from kingdom to genus; signaling pathway analysis; correlation with serum cholesterol
Year:
2021
Region / city:
Tianjin, China
Subject:
Stem Cell Therapy, Neurological Function, Ischemic Stroke, Gut Microbiota
Document type:
Research Article
Organization / Institution:
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin Key Laboratory of Translational Research of TCM Prescription and Syndrome
Author:
Zhao LN, Ma SW, Xiao J, Yang LJ, Xu SX, Zhao L
Target audience:
Researchers, Healthcare professionals, Medical practitioners
Period of validity:
Not specified
Approval date:
December 11, 2021
Date of revisions:
July 6, 2021
Publication date:
December 26, 2021
Year:
2026
Region / City:
Marseille, France; Valladolid, Spain; Paris, France
Subject:
Food science, nutrition, microbiota, vitamin D
Document Type:
Research article
Institution:
Aix Marseille Univ, INRAE, INSERM, University of Valladolid, Institut Pasteur, CNRS, CIML
Authors:
Ángela Bravo-Núñez, Angélique Berthomé, Charlotte Sabran, Donato Vairo, Jean-Charles Martin, Katherine Alvarado-Ramos, Benoit Chassaing, Julie Tomas, Emmanuelle Reboul
Target Audience:
Researchers in nutrition, microbiology, and food science
Study Duration:
11 weeks in mice
Methodology:
In vitro and in vivo experiments, plasma and microbiota analysis
Key Findings:
Plant-based emulsifiers (pea protein and arabinoxylans) maintain vitamin D3 bioavailability and reduce serum LPS-specific IgG compared to synthetic emulsifiers; T80 modifies microbiota and gut epithelium distance
Keywords:
Tween 80, polysorbate, pea protein, arabinoxylans, cholecalciferol, bioavailability, inflammation, intestine, microbiota, mucus
Correspondence:
Emmanuelle Reboul, C2VN, Faculty of Medicine, Marseille, France, [email protected]; Ángela Bravo-Núñez, University of Valladolid, Spain, [email protected]
Year:
2026
Organization:
BIOCODEX MICROBIOTA FOUNDATION
Headquarters:
7 Avenue Gallieni, GENTILLY, France
Type of document:
Information notice
Purpose:
Personal data processing for research participation
Data controller:
BIOCODEX MICROBIOTA FOUNDATION
Legal framework:
Regulation (EU) 2016/679 (GDPR)
Data retention period:
Up to 6 years depending on award outcome
Recipients:
Foundation board, international scientific committee, BIOCODEX administrative staff, service providers
International data transfer:
Allowed outside the European Union
Rights of individuals:
Access, rectification, erasure, restriction, objection
Contact:
DPO BIOCODEX, [email protected]
Target audience:
Project applicants and participants
Document structure:
Project leader details, organization information, grant managing organization, project summary, description, methodology, team details, partner teams, bibliography, budget, schedule
Confidentiality:
Non-confidential summary and scientific confidential summary provided
Year:
2026
Region / City:
International
Subject:
Biology, Aging, Endocrinology, Microbiota
Document Type:
Research Article
Institution:
Haveri Institute of Medical Sciences; Sri Madhusudan Sai Institute of Medical Sciences; University Hospital of Gabès; BGS Global Institute of Medical Sciences
Authors:
Harish Rangareddy, Venkateshappa Chikkanarayanappa, Rajhi Hayfa, Ashakiran Srinivasaiah, Reshma Devarajachar
Keywords:
leptin, microbiota, longevity, aging, cellular processes, telomeres, insulin, neuroendocrine functions
Target Audience:
Researchers, clinicians, students in biomedical sciences
Period Covered:
Current understanding as of 2026
Publication Date:
2026
Year:
2017
Region / city:
United Kingdom
Subject:
Faecal microbiota transplant (FMT) for Clostridium difficile infection and other indications
Document type:
Clinical guidelines
Organization / institution:
British Society of Gastroenterology (BSG) and Healthcare Infection Society (HIS)
Authors:
Working group of BSG and HIS
Target audience:
Healthcare professionals, clinicians
Period of validity:
Ongoing (as of publication)
Approval date:
Not specified
Date of revisions:
Not specified
Scope:
Guidelines for the use of faecal microbiota transplant in treating Clostridium difficile infection (CDI) and other clinical conditions
Clinical management:
Recommendations for patient selection, donor selection, and FMT administration
Economic aspects:
Cost-effectiveness of FMT compared to traditional therapies for CDI
Note:
Year
Subject:
Medical consent
Document Type:
Consent form
Target Audience:
Patient, Legal Guardian
Context:
Medical consent form for fecal microbiota transplantation outlining procedure, risks, and alternatives.
Year:
2026
Species:
Lymantria dispar
Experimental Groups:
Control, GM, GI
Analysis Methods:
Venn diagram, LEfSe cladogram, PICRUSt
Sample Stage:
5th instar larvae
Plant Treatment:
GM leaves, GI leaves, nonmycorrhizal-colonized leaves
Significance Threshold:
P < 0.05
Type of Document:
Supplementary Figures for Research Article
Year:
2023
Region / City:
Unknown
Topic:
Gestational Diabetes, Gut Microbiota, Newborns
Document Type:
Research Study
Author:
Unknown
Target Audience:
Researchers, Healthcare Professionals
Period of Validity:
Not specified
Approval Date:
Not specified
Date of Changes:
Not specified
Year:
2025
Note:
Region / city
Topic:
Medical Education, Transplantation
Document type:
Announcement
Institution:
American Journal of Transplantation
Target audience:
Physicians, surgeons, healthcare providers in transplantation
Period of validity:
Starting June 1st, 2025
Year:
2020
Region / City:
United States
Topic:
Organ and tissue donation, transplantation
Document Type:
FAQ
Organization:
Donate Life America
Target Audience:
General public, potential organ donors, families
Period of Action:
April (National Donate Life Month)
Approval Date:
Not specified
Date of Changes:
Not specified
Year:
2022
Region / City:
United States
Topic:
Organ and Tissue Donation, Transplantation
Document Type:
Report
Organization:
Donate Life America
Author:
Not specified
Target Audience:
General public, medical professionals
Period of validity:
Not specified
Approval Date:
March 17, 2023
Modification Date:
Not specified
Year:
Not specified
Region / City:
Not specified
Topic:
Haematopoietic Stem Cell Transplantation Nursing
Document Type:
Terms of Reference
Organization:
European Society for Blood and Marrow Transplantation (EBMT)
Author:
Not specified
Target Audience:
Nurses and healthcare professionals involved in HSCT
Period of Validity:
Not specified
Approval Date:
Not specified
Date of Changes:
Not specified
Year:
2023
Region / City:
United States
Topic:
Hematopoietic Cell Transplantation, Cellular Therapies, Research Databases
Document Type:
Consent Form
Organization / Institution:
CIBMTR (Center for International Blood and Marrow Transplant Research)
Author:
CIBMTR
Target Audience:
Patients and/or parents/legal guardians of recipients of hematopoietic cell transplants or cellular therapies
Effective Period:
N/A
Approval Date:
N/A
Amendment Date:
N/A
Year:
1998
Region / City:
Bahrain
Type of Document:
Legislative Decree
Authority / Institution:
Emir of the State of Bahrain
Author:
Isa bin Salman Al Khalifa
Publication Date:
13 June 1998
Period of Application:
From publication in the Official Gazette
Subject Matter:
Human organ transfer and transplantation
Relevant Laws Referenced:
Constitution; Emiri Order No. (4) of 1975; Legislative Decree No. (7) of 1989 regarding the Practice of Human Medicine and Dentistry
Minister Responsible:
Minister of Health
Medical Oversight:
Specialised medical committees for organ removal and transplantation
Year:
2022
Region / City:
Detroit
Topic:
Transplantation, Pancreas
Document Type:
Educational Lecture
Institution:
Henry Ford Health System
Author:
Not listed
Target Audience:
Transplant Institute Faculty
Period of Validity:
8/29/2022
Approval Date:
12/28/2021
Date of Updates:
08/01/2022
Accreditation:
Accredited by ACCME
Maximum Credit:
1.00 AMA PRA Category 1 Credit(s)™
Faculty Disclosure:
All relevant financial relationships have been mitigated
Accessibility:
Accessible for individuals with disabilities
Context:
Educational lecture providing an update on pancreas transplantation, focusing on federal regulations, quality initiatives, research findings, cancer in transplantation, and transplantation in the COVID era.
Year:
2017
Region / city:
Wellington, New Zealand
Theme:
Organ donation and transplantation
Document type:
National strategy report
Organization:
Ministry of Health
Author:
Hon Dr Jonathan Coleman
Target audience:
General public, healthcare professionals, policymakers
Period of validity:
Not specified
Approval date:
June 2017
Amendment date:
Not specified
ISBN:
978-1-98-850267-0 (print), 978-1-98-850268-7 (online)
License:
Creative Commons Attribution 4.0 International
Intended outcome:
Increase deceased organ donation
Context:
Public consultation and sector collaboration
Year:
2026
Region / City:
Europe
Field:
Transplantation Surgery
Document Type:
Application Form
Organization:
European Board of Surgery
Author:
Applicant (physician)
Target Audience:
Surgeons seeking EBSQ certification
Required Attachments:
Medical degree certificates, surgical specialty certificates, transplantation training certificates
Training Duration:
Years …, Months …
Declaration Date:
…
Signatures:
Applicant, Principal Trainers