№ files_lp_4_process_2_73113
Year: 1990–2016
Region / City: International, multicenter
Topic: Pediatric febrile urinary tract infections, antibiotic efficacy
Document Type: Systematic review and meta-analysis
Institution / Organization: St George’s University of London; University of Athens; Institut National de la Santé et de la Recherche Médicale, Université Paris Diderot; University Children’s Hospital Basel; University of Pennsylvania School of Medicine
Authors: Konstantinos Vazouras, Romain Basmaci, Julia Bielicki, Laura Folgori, Theoklis Zaoutis, Mike Sharland, Yingfen Hsia
Study Population: Children aged 0–18 years with febrile urinary tract infections without major underlying conditions
Number of Studies Reviewed: 30 clinical trials
Total Cases Analyzed: 3,913
Antibiotics Evaluated: Cephalosporins, aminoglycosides, other antimicrobials
Key Outcomes: Clinical cure rates, microbiological cure rates, treatment failure rates
Data Sources: Medline, Embase, Cochrane Central
Inclusion Criteria: Randomized clinical trials reporting on clinical and/or microbiological efficacy of antibiotics in pediatric febrile UTIs
Exclusion Criteria: Lower urinary tract infections, patients with underlying conditions, long-term endpoints >1 month
Price: 8 / 10 USD
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