№ files_lp_3_process_7_099354
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The document is an essay exploring the psychological factors behind the "bystander effect," using real-life examples and experiments to illustrate why people often fail to intervene in emergencies.
Year: 2016
Region / City: New York City, USA
Topic: Psychology, Social Behavior
Document Type: Essay
Author: Dorothy Barkin
Target Audience: Students, Researchers, General Public
Period of Application: Ongoing
Date of Approval: Not specified
Date of Changes: Not specified
Price: 8 / 10 USD
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Dolaflexin: A Novel Antibody-Drug Conjugate Platform Featuring High Drug Loading and Controlled Bystander Effect
Year: 2026
Field: Biotechnology / Pharmacology
Document type: Research article
Institution: Mersana Therapeutics
Authors: Aleksandr Yurkovetskiy, Natalya Bodyak, Mao Yin, Joshua D. Thomas, Susan M. Clardy, Patrick R. Conlon, Cheri A. Stevenson, Alex Uttard, LiuLiang Qin, Dmitry R. Gumerov, Elena Ter-Ovaneysan, Charlie Bu, Alex Johnson, Venu R. Gurijala, Dennis McGillicuddy, Michael J. DeVit, Laura L. Poling, Marina Protopopova, Ling Xu, Qingxiu Zhang, Peter U. Park, Donald A. Bergstrom, Timothy B. Lowinger
Keywords: Antibody-drug conjugate, polymer, bystander effect, auristatin
Target organism: Human HER2-positive and low-HER2-expression tumors
Experimental models: Mice, rats, cynomolgus monkeys
Payload: Auristatin F-hydroxypropylamide
Drug-antibody ratio (DAR): 10–15
Comparative analysis: Trastuzumab-Dolaflexin vs ado-trastuzumab emtansine
Safety evaluation: Pharmacokinetics, tumor regressions, toxicity profile
Description: Original research article detailing the synthesis, characterization, and in vivo evaluation of Dolaflexin, an auristatin-based antibody-drug conjugate with a high drug-antibody ratio and controlled bystander effect, including comparative studies with existing ADC platforms.
Active Bystander Champion Information and Role Description
Year: 2026
Region / City: Nottingham and Nottinghamshire
Topic: Workplace culture and inclusion
Document Type: Role description / guidance
Organization: Nottingham and Nottinghamshire ICS
Author: Not specified
Target Audience: Staff interested in becoming Active Bystander Champions
Implementation Period: 6 months
Approval Date: Not specified
Training Duration: 1 day workshop plus up to 5 virtual action learning sets and 48 hours self-directed learning
Role Responsibilities: Intervene in unacceptable workplace behaviour, promote inclusivity, model ethical and respectful conduct
Support Requirements: Line manager approval for time release, engagement with Organisational Lead
Community Engagement: Participation in Community of Practice, coaching, mentoring, and learning events
Evaluation: Programme learning collated anonymously and shared with ICS and regional/national leads
Dorothy "Dottie" D. LaBranche Obituary
Date of Birth: November 4, 1927
Date of Death: June 27, 2018
Family: Survived by daughters Diana Marse (Kevin) and Joanne Weber (Nolan), daughter-in-law Robin LaBranche, sisters Yvonne Richoux and Catherine Webre, six grandchildren, and 12 great-grandchildren. Preceded in death by husband Murphy LaBranche Sr., son Murphy "Jay" LaBranche Jr., brother Lloyd and Alton Duhe, sister Loraine LaBranche, and parents Sidney and Leoda Duhe.
Type of Document: Obituary
Location: LaPlace, LA
Event: Funeral Service
Date of Service: July 2, 2018
Officiating: St. Joan of Arc Catholic Church, LaPlace, LA
Burial Site: St. Peter Cemetery, Reserve, LA
Source: The New Orleans Advocate (LA), Jun. 29 to Jul. 2, 2018
CURRICULUM VITAE OF DOROTHY FARRAR EDWARDS, MAY 2018
Year: 2018
Location: Madison, Wisconsin, USA
Field: Occupational Therapy and Psychology
Document Type: Curriculum Vitae
Institution: University of Wisconsin-Madison; Washington University in St. Louis
Author: Dorothy Farrar Edwards, Ph.D.
Academic Positions: Professor, Chair, Director, Research Scientist
Education: B.A. in Psychology, Ph.D. in Experimental Psychology
Publications: Peer-reviewed journal articles in occupational therapy, geriatrics, and neurology
Minutes of the Undergraduate Programs Committee Meeting, Dorothy F. Schmidt College of Arts and Letters, Florida Atlantic University — November 21, 2014
Institution: Florida Atlantic University
College: Dorothy F. Schmidt College of Arts and Letters
Committee: Undergraduate Programs Committee (UPC)
Document Type: Meeting Minutes
Meeting Date: November 21, 2014
Location: Florida Atlantic University
Chair: Clifford Brown
Participants: Clifford Brown; Stephen Charbonneau; Eric Hanne; Laura Joella; Marina Banchetti; Kathryn Johnston; Myriam Ruthenberg; Sika Dagbovie-Mullins; Linda Johnson
Agenda Topics: Program changes; new course proposals; course changes; committee reports; policy updates
Programs and Departments Mentioned: Anthropology; SCMS; History; Music; Philosophy; Theatre; LLCL; English
Key Actions: Approval of program changes, approval of new courses, approval of course modification, review of electronic voting procedures
Related Bodies: University Undergraduate Programs Committee (UUPC); Honors Council; UFS Steering Committee
Meeting Start Time: 2:05
Meeting End Time: 2:50
Curriculum Vitae of Dorothy Wanja Nyingi, PhD
Year: 2007
Region / City: Nairobi, Kenya
Field: Freshwater Biology, Ichthyology
Document Type: Curriculum Vitae
Organization / Institution: National Museums of Kenya
Author: Dorothy Wanja Nyingi
Target Audience: Academic and scientific community
Period of Activity: 1998 - Present
Date of Approval: Not specified
Date of Changes: Not specified
Peace Papers of Dorothy Freeborn Martin: Interim Catalogue
Year: 1929-1972
Region / City: Bradford, United Kingdom
Subject: Peace Activism, Pacifism, Nuclear Disarmament, Civil Defence
Document Type: Collection (Fonds)
Organization: J.B. Priestley Library, University of Bradford
Author: Dorothy Freeborn Martin
Target Audience: Researchers, Academics, Students
Period of Action: 1929-1972
Approval Date: N/A
Date of Revisions: June 2016
Dorothy L. Goosby: A Trailblazer in Community Service and Public Leadership
Year: 2021
Region / City: Hempstead
Theme: Community service, Leadership, Advocacy
Document type: Biography
Organization / Institution: Town of Hempstead
Author: Dorothy L. Goosby
Target audience: General public
Period of validity: N/A
Approval date: N/A
Date of changes: N/A
Topics: Barkin Bystander Dorothy