№ files_lp_4_process_3_073636
File format: docx Character count: 639 File size: 62 KB
Year: Not specified
Region / City: Not specified
Topic: Multivariate Cox Model, Cancer Research, Biomarkers
Document Type: Research Report
Organization / Institution: Not specified
Author: Not specified
Target Audience: Researchers, Medical Professionals
Period of Validity: Not specified
Approval Date: Not specified
Date of Changes: Not specified
Context: A statistical analysis of the relationship between IL-1B and IL-1R1 expression in tumor and stroma with respect to distant recurrence and bone involvement in cancer patients using a multivariate Cox model.
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Supplemental Figure Legends for Figures S1–S5 on mDia2 and MIRO1 Functions in Fibroblasts and Tumor Stroma
Document Type: Supplementary figure legends
Field: Cell biology
Subfield: Mitochondrial dynamics and cytoskeletal regulation
Biological Material: Human primary dermal fibroblasts, CAFs, NFs, keratinocytes, hepatocytes
Proteins Studied: mDia2, MIRO1, GM130, calnexin, α-tubulin, vinculin
Experimental Techniques: Immunofluorescence, Western blot, qRT–PCR, Seahorse analysis, ATP biosensor imaging, PLA assay
Data Type: Quantitative imaging and biochemical analysis
Statistical Methods: One-way ANOVA, two-way ANOVA, Student’s t-test with Bonferroni post-hoc test
Sample Size: n values ranging from 3 to 40 depending on experiment
Key Variables: Mitochondrial network structure, ATP levels, protein expression, fluorescence intensity
Context: Cancer stroma and cellular metabolism
Species: Human
Measurement Units: Micrometers (μm), fluorescence intensity, transcripts per million (TPM)
Topics: IL-1B IL-1R1 Stroma