№ lp_2_1_05794
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Genome-wide association studies have identified a genetic link between PTPN2 and inflammatory bowel disease, highlighting its role in immune regulation and intestinal homeostasis.
Year: 2015
Region / City: Zurich, Switzerland
Topic: Inflammatory bowel disease
Document type: Journal Article
Organization / Institution: University Hospital Zurich, University of California Riverside
Author: Marianne R Spalinger, Declan F McCole, Gerhard Rogler, Michael Scharl
Target audience: Researchers, medical professionals
Period of validity: N/A
Approval date: N/A
Modification date: N/A
Price: 8 / 10 USD
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Risk of hepatitis B virus reactivation in oncological patients treated with tyrosine kinase inhibitors: A case report and literature analysis
Journal: World Journal of Gastroenterology
Manuscript NO: 90838
Manuscript Type: Letter to the Editor
Authors: Francesca Colapietro, Nicola Pugliese, Antonio Voza, Alessio Aghemo, Stella De Nicola
Affiliations: Department of Biomedical Sciences, Humanitas University, Milan, Italy; Division of Internal Medicine and Hepatology, Department of Gastroenterology, Humanitas Research Hospital, Milan, Italy; Department of Emergency, Humanitas Research Hospital, Milan, Italy
Corresponding Author: Francesca Colapietro, MD, Department of Biomedical Sciences, Humanitas University, Milan, Italy, [email protected]
Received: December 15, 2023
Revised: January 11, 2024
Accepted: February 18, 2024
Keywords: Chronic hepatitis B, Reactivation, Nucleoside analogue, Tyrosine kinase inhibitors, Onco-hematology
Study Type: Case report and literature review
Patient Details: 67-year-old Caucasian male with chronic lymphocytic leukemia, HBsAg-/anti-HBc+
Treatment: Tyrosine kinase inhibitors, specifically acalabrutinib
Clinical Outcome: HBV reactivation with liver failure, treated with nucleos(t)ide analogues
Letter to the Editor: Recent Research in Achondroplasia in Childhood: A special focus on new selective FGFR3 tyrosine kinase inhibitors
Year: 2025
Region / city: Not specified
Topic: Achondroplasia, FGFR3, Tyrosine Kinase Inhibitors, Genetic Disorders
Document Type: Research Letter
Organization: Not specified
Author(s): Not specified
Target Audience: Medical professionals, researchers
Period of validity: Not specified
Approval Date: Not specified
Date of Changes: Not specified
Contextual description: A research letter summarizing recent advancements in the treatment and genetic understanding of achondroplasia, particularly focusing on selective FGFR3 tyrosine kinase inhibitors.
Comparative Analysis of Cluster A Mycobacteriophage Serine and Tyrosine Integrases
Year: 2024
Region / City: Longview, TX
Theme: Mycobacteriophages, Serine Integrase, Tyrosine Integrase
Document Type: Research Paper
Author: Megan T LeBlanc, Varma Parinita, Josh D McLoud, Frederick N Baliraine
Target Audience: Scientists, Researchers in Biotechnology and Genetic Engineering
Period of Action: Not specified
Approval Date: Not specified
Date of Changes: Not specified
Topics: phosphatase non-receptor tyrosine